Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alan Zhu"'
Autor:
Jun Yang, Qiuxia Lu, Weihua Qi, Ryann D. Kolb, Lei Wang, Yuan Li, Sida Li, Yihui Lin, Jiayi Liu, Waleed Mourad, Farzaneh MirkhaghaniHaghighi, Tubin Slavisa, Xiaodong Wu, Wei-Ciang You, Eddy Yang, Alex Hanlon, Alan Zhu, Weisi Yan
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeBulky tumor remains as a challenge to surgery, chemotherapy and conventional radiation therapy. Hence, in efforts to overcome this challenge, we designed a novel therapeutic paradigm via strategy of Stereotactic Central/Core Ablative Radiation
Externí odkaz:
https://doaj.org/article/1e4518952cba4831b9c19b3315ff95c7
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 44, Iss , Pp 100691- (2024)
Spatially Fractionated Radiation Therapy (SFRT) is a form of radiotherapy that delivers a single large dose of radiation within the target volume in a heterogeneous pattern with regions of peak dosage and regions of under dosage. SFRT types can be de
Externí odkaz:
https://doaj.org/article/863e379c5d6e46b2a5d0565d37eac1e2
Publikováno v:
Frontiers in Dental Medicine, Vol 3 (2022)
Despite over 50 years of research into the immunology of periodontal disease, the precise mechanisms and the role of many cell types remains an enigma. Progress has been limited by the inability to determine disease activity clinically. Understanding
Externí odkaz:
https://doaj.org/article/90cc5d62ace94bcdb8c30b14eb1c8d19
Publikováno v:
Molecular Pharmaceutics. 19:4191-4198
An in vitro drug release test was developed to establish a level A in vitro-in vivo correlation (IVIVC) for predicting the in vivo performance of potassium chloride extended-release (ER) matrix tablets. Three ER formulations of potassium chloride wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08b6d88313cc5d36fda1b0694930cfb
https://doi.org/10.1021/acs.molpharmaceut.2c00568
https://doi.org/10.1021/acs.molpharmaceut.2c00568
Publikováno v:
Chemical Communications. 57:2633-2636
Establishing quantitative structure-property relationships for the rational design of small molecule drugs at the early discovery stage is highly desirable. Using natural language processing (NLP), we proposed a machine learning model to process the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa5e889753def16c17ee507490cb2b5
https://doi.org/10.1039/d0cc07384a
https://doi.org/10.1039/d0cc07384a
Publikováno v:
Metabolomics : Official journal of the Metabolomic Society. 15(7)
Bladder cancer (BCa) is one of the most common and aggressive cancers. It is the sixth most frequently occurring cancer in men and its rate of occurrence increases with age. The current method of BCa diagnosis includes a cystoscopy and biopsy. This p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8bf4674c8b56feea3e21879837e5e42
https://pubmed.ncbi.nlm.nih.gov/31222577
https://pubmed.ncbi.nlm.nih.gov/31222577
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 122
Hydroxypropyl methylcellulose acetate succinate (HPMC-AS) is one of the most widely used polymers used in amorphous solid dispersions (ASD) for solubility and bioavailability enhancement of poorly water-soluble drugs. Once released from ASDs, HPMC-AS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e48750f7c980e17edb7eb4ccc540419
https://pubmed.ncbi.nlm.nih.gov/30006181
https://pubmed.ncbi.nlm.nih.gov/30006181
Surface Enrichment and Depletion of the Active Ingredient in Spray Dried Amorphous Solid Dispersions
Publikováno v:
Pharmaceutical Research. 35
To study the effects of physicochemical properties of drug and polymer, as well as the drug-polymer interactions, on the surface composition of SDDs. Ethanol solutions containing a model drug (IMC, NMP or FCZ) and a model polymer (PVPK12, PVPK30 or P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df5a589f6aa510ca0e404ff548f4d42
https://doi.org/10.1007/s11095-018-2345-1
https://doi.org/10.1007/s11095-018-2345-1
Autor:
Zengjun Li, Jianyong Li, Jianda Hu, Chunyan Ji, Jianfeng Zhou, Kaiyang Ding, Renbin Zhao, Sujun Gao, Zhixin Xu, Yan Li, Yu Hu, Huilai Zhang, Zhongjun Xia, Shunqing Wang, Shenmiao Yang, Xin Wang, Lihong Liu, Wei Xu, Zunmin Zhu, Bing Xu, Ting Liu, Wei Zhang, Alan Zhu, Bin Zhang, Yongping Song
Publikováno v:
Blood. 134:4319-4319
Bruton's Tyrosine Kinase (BTK) plays a critical role in B-cell receptor (BCR) signaling, which mediates B-cell proliferation, migration, and adhesion. As a therapeutic target, its clinical significance has been well established in multiple subtypes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b1d8506e2d02eb847c11099bece8fe5
https://doi.org/10.1182/blood-2019-123331
https://doi.org/10.1182/blood-2019-123331
Publikováno v:
Journal of pharmaceutical sciences. 105(9)
Isothermal microcalorimetry was utilized to monitor the crystallization process of amorphous ritonavir (RTV) and its hydroxypropylmethylcellulose acetate succinate-based amorphous solid dispersion under various stressed conditions. An empirical model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d77ad3e260dda47149f70871caf010
https://pubmed.ncbi.nlm.nih.gov/27185539
https://pubmed.ncbi.nlm.nih.gov/27185539