Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alan Yiu Wah Lee"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/8caac6b26f0a478589141ab51531c77a
Autor:
Si Yun Ng, Alan Yiu Wah Lee
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Traumatic brain injury (TBI) remains one of the leading causes of morbidity and mortality amongst civilians and military personnel globally. Despite advances in our knowledge of the complex pathophysiology of TBI, the underlying mechanisms are yet to
Externí odkaz:
https://doaj.org/article/0855dd20f70741d3bde192a8209ae36a
Autor:
Alan Yiu Wah Lee, Si Yun Ng
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Traumatic brain injury (TBI) remains one of the leading causes of morbidity and mortality amongst civilians and military personnel globally. Despite advances in our knowledge of the complex pathophysiology of TBI, the underlying mechanisms are yet to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406f5655a1515556ec282fbacee3bcc3
https://doi.org/10.3389/fncel.2019.00528
https://doi.org/10.3389/fncel.2019.00528
Autor:
Alan Yiu Wah Lee, Janice Wai Sze Law
Publikováno v:
Journal of Signal Transduction
Gliomas are the most common tumor in the central nervous system. High-grade glioblastomas are characterized by their high invasiveness and resistance to radiotherapy, leading to high recurrence rate and short median survival despite radical surgical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fd3ec179232ff5b6cace112bb9b9c0
https://doi.org/10.1155/2012/902854
https://doi.org/10.1155/2012/902854
Autor:
Xinhua Li, Alan Yiu Wah Lee
Publikováno v:
Journal of Biological Chemistry. 285:32436-32445
Semaphorins and plexins are implicated in the progression of various types of cancer, although the molecular basis has not been fully elucidated. Here, we report the expression of plexin-B3 in glioma cells, which upon stimulation by its ligand Sema5A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd47c24efbf52ad6f9c8a5d159a4685
https://doi.org/10.1074/jbc.m110.120451
https://doi.org/10.1074/jbc.m110.120451
Publikováno v:
European Journal of Biochemistry. 230:1059-1065
Sorbitol dehydrogenase is one of the enzymes in the polyol pathway, which is thought to be implicated in the pathogenesis of diabetic complications. The cDNA encoding mouse sorbitol dehydrogenase was cloned from a liver library and its sequence was d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00896942b16c548f7366c85c4f9df71b
https://doi.org/10.1111/j.1432-1033.1995.1059g.x
https://doi.org/10.1111/j.1432-1033.1995.1059g.x
Publikováno v:
Journal of Neuroscience Methods. 158:56-63
Mouse neuroblastoma cell lines are often used in lieu of mouse primary neurons in ex vivo experiments, as they provide an easier platform for transfection, compared to the latter. A well-known inherent problem with this strategy is the relatively low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a32685362243811d1a446609abb4696
https://doi.org/10.1016/j.jneumeth.2006.05.017
https://doi.org/10.1016/j.jneumeth.2006.05.017
Autor:
Zhao Feng Peng, Lily-Lily Chiu, Nam Sang Cheung, Jayapal Manikandan, Alan Yiu Wah Lee, Robert Z. Qi, Elaine H. J. Yew, W. L. Ng, Matthew Whiteman, Meng S. Choy, Barry Halliwell, Alirio J. Melendez, Jeyaseelan Kandiah, Evelyn Siew-Chuan Koay
Publikováno v:
Journal of Neurochemistry. 94:943-956
Although inhibition of the ubiquitin proteasome system has been postulated to play a key role in the pathogenesis of neurodegenerative diseases, studies have also shown that proteasome inhibition can induce increased expression of neuroprotective hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4151728e16ef7dc04d45f1e7ad501e77
https://doi.org/10.1111/j.1471-4159.2005.03220.x
https://doi.org/10.1111/j.1471-4159.2005.03220.x
Autor:
Philip M Beart, Alan Yiu Wah Lee, V. H. Koh, Nam Sang Cheung, Evelyn Siew-Chuan Koay, Matthew Whiteman, Kim Ping Wong, L. L. Chiu, Meng S. Choy, Hong-Jian Zhu, Heung-Chin Cheng, T. S. Teo, Boon-Huat Bay, Robert Z. Qi, Barry Halliwell
Publikováno v:
Cellular and Molecular Life Sciences. 61:1926-1934
The tumor suppressor function of PTEN is attributed to its phospholipid phosphatase activity that dephosphorylates the plasma membrane phosphatidylinositol-(3,4,5)-triphosphate [PtdIns(3,4,5)P3]. Implicit in this notion is that PTEN needs to be targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb8230ae4df92439bf537c7f87f0c53
https://doi.org/10.1007/s00018-004-4127-7
https://doi.org/10.1007/s00018-004-4127-7
Publikováno v:
Proceedings of the National Academy of Sciences. 92:2780-2784
Aldose reductase (AR) has been implicated in the etiology of diabetic cataract, as well as in other complications. However, the role of AR in these complications remains controversial because the strongest supporting evidence is drawn from the use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dafe8acb1f21c349e33a2af0365d253
https://doi.org/10.1073/pnas.92.7.2780
https://doi.org/10.1073/pnas.92.7.2780