Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alan Ying-Hsu Wang"'
Autor:
Shuhe Tsai, Louis-Alexandre Fournier, Emily Yun-Chia Chang, James P Wells, Sean W Minaker, Yi Dan Zhu, Alan Ying-Hsu Wang, Yemin Wang, David G Huntsman, Peter C Stirling
Publikováno v:
PLoS Genetics, Vol 17, Iss 4, p e1009238 (2021)
ARID1A is a core DNA-binding subunit of the BAF chromatin remodeling complex, and is lost in up to 7% of all cancers. The frequency of ARID1A loss increases in certain cancer types, such as clear cell ovarian carcinoma where ARID1A protein is lost in
Externí odkaz:
https://doaj.org/article/330f9ddec6dc43c09ea6f032eae0dc87
Autor:
Emily Yun-Chia Chang, Shuhe Tsai, Maria J. Aristizabal, James P. Wells, Yan Coulombe, Franciele F. Busatto, Yujia A. Chan, Arun Kumar, Yi Dan Zhu, Alan Ying-Hsu Wang, Louis-Alexandre Fournier, Philip Hieter, Michael S. Kobor, Jean-Yves Masson, Peter C. Stirling
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Accumulations of R-loops can lead to genome instability. Here the authors reveal a role for the MRN complex in suppressing R-loops and associated DNA damage at transcription–replication conflicts.
Externí odkaz:
https://doaj.org/article/a6da048a2a604ec29f09e5727eff77ce
Autor:
David G. Huntsman, Yemin Wang, Alan Ying-Hsu Wang, Peter C. Stirling, James P. Wells, Yi Dan Zhu, Emily Yun-Chia Chang, Sean W. Minaker, Shuhe Tsai, Louis-Alexandre Fournier
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 4, p e1009238 (2021)
PLoS Genetics, Vol 17, Iss 4, p e1009238 (2021)
ARID1A is a core DNA-binding subunit of the BAF chromatin remodeling complex, and is lost in up to 7% of all cancers. The frequency of ARID1A loss increases in certain cancer types, such as clear cell ovarian carcinoma where ARID1A protein is lost in
Autor:
Arun Kumar, Yan Coulombe, Maria J. Aristizabal, Jean-Yves Masson, Shuhe Tsai, Yi Dan Zhu, Peter C. Stirling, Louis-Alexandre Fournier, Emily Yun-Chia Chang, Philip Hieter, Yujia Alina Chan, Michael S. Kobor, Franciele F. Busatto, Alan Ying-Hsu Wang, James P. Wells
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
Ectopic R-loop accumulation causes DNA replication stress and genome instability. To avoid these outcomes, cells possess a range of anti-R-loop mechanisms, including RNaseH that degrades the RNA moiety in R-loops. To comprehensively identify anti-R-l
Autor:
Philip Dawe, Alan Ying-Hsu Wang, Adam Greene, Pang Y. Young, Shadhiya Al Khan, Monika Hudoba, Andrew W. Shih, Erik N. Vu
Publikováno v:
The journal of trauma and acute care surgery. 87(3)
BACKGROUND The use of massive transfusion protocols (MTPs) in the resuscitation of hemorrhaging trauma patients ensures rapid delivery of blood products to improve outcomes, where the decision to trigger MTPs early is important. Scores and tools to p