Zobrazeno 1 - 10
of 594
pro vyhledávání: '"Alan Wells"'
Autor:
Tung Phan, David Gerlowski, Melissa McCullough, Jamie Gribschaw, William Pasculle, Alan Wells
Publikováno v:
Journal of Clinical Virology Plus, Vol 4, Iss 2, Pp 100177- (2024)
Rapid laboratory testing is essential to detect HSV in the lower respiratory tract to allow rapid treatment decisions. We evaluated the clinical performance of the Simplexa HSV 1 & 2 Direct assay in bronchoalveolar lavage. This assay is highly sensit
Externí odkaz:
https://doaj.org/article/88a1ac5e3ea34ee687c29f7063d11d36
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7133 (2024)
Breast cancer is most common in women, and in most cases there is no evidence of spread and the primary tumor is removed, resulting in a ‘cure’. However, in 10% to 30% of these women, distant metastases recur after years to decades. This is due t
Externí odkaz:
https://doaj.org/article/c73600a59224404abd6d7ce982383ffc
Publikováno v:
Journal of Clinical Virology Plus, Vol 3, Iss 4, Pp 100169- (2023)
The demand for molecular virology testing continues to grow in clinical laboratories worldwide. The Alinity m system is a fully automated, continuous, random-access molecular diagnostic analyzer that was designed to streamline the laboratory workflow
Externí odkaz:
https://doaj.org/article/bcf3132312654cb3ac7724af3d5e6f23
Autor:
Hanshuang Shao, Alan Wells
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionThe abnormal expression and mutagenesis of EGFR drives both the development and progression of a multitude of human cancers. Further mutations within the tyrosine kinase region of the EGFR subsequently contribute to resistance to targeted
Externí odkaz:
https://doaj.org/article/50d234c802714403a118166c29fec368
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 5, Pp 635-650 (2022)
Objective: Early prostate cancer micrometastatic foci undergo a mesenchymal to epithelial reverting transition, not only aiding seeding and colonization, but also rendering the tumor cells generally chemoresistant. We previously found that upregulate
Externí odkaz:
https://doaj.org/article/1071049b876c485a97e0d5d374a17329
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Interferon-γ (IFNγ) is a cytokine with limited evidence of benefit in cancer clinical trials to date. However, it could potentially play a role in potentiating anti-tumor immunity in the immunologically "cold" metastatic castration-resista
Externí odkaz:
https://doaj.org/article/f71d51b78877491abc146d9ecf424891
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283749 (2023)
Axl, a member of the TAM receptor family has been broadly suggested to play a key role in tumor metastasis. However, the function of Axl in the invasion and metastasis of melanoma, the most lethal skin cancer, remains largely unknown. In the present
Externí odkaz:
https://doaj.org/article/f3651d8f5a064d4bbba4c327094bf564
Mini-evaluation of the Lyra SARS-CoV-2 assay to detect Omicron BA.1 and BA.2 in nasopharyngeal swabs
Publikováno v:
Journal of Clinical Virology Plus, Vol 2, Iss 4, Pp 100118- (2022)
Externí odkaz:
https://doaj.org/article/ef417884b9f945bf89f3c8008c047bf6
Autor:
Stephanie L. Mitchell, Steven Orris, Tanner Freeman, Megan C. Freeman, Michelle Adam, Meredith Axe, Jamie Gribschaw, Joe Suyama, Alejandro Hoberman, Alan Wells
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background Antigen testing offers rapid and inexpensive testing for SARS-CoV-2 but concerns regarding performance, especially sensitivity, remain. Limited data exists for use of antigen testing in asymptomatic patients; thus, performance and
Externí odkaz:
https://doaj.org/article/8f3d6c8eb2384c37bd1a4b13e8bc1924
Publikováno v:
Journal of Clinical Virology Plus, Vol 2, Iss 2, Pp 100067- (2022)
Accurate and rapid laboratory tests are essential for the prompt diagnosis of COVID-19, which is important to patients and infection control. The Xpert Xpress SARS-CoV-2 test is a real-time RT-PCR intended for the qualitative detection of nucleic aci
Externí odkaz:
https://doaj.org/article/e97cef40bfab4238bca98b8fab0cec86