Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Alan W Patrick"'
Autor:
Paul M. McKeigue, Athina Spiliopoulou, Stuart McGurnaghan, Marco Colombo, Luke Blackbourn, Timothy J. McDonald, Suna Onengut-Gomuscu, Stephen S. Rich, Colin N. A. Palmer, John A. McKnight, Mark W. J. Strachan, Alan W. Patrick, John Chalmers, Robert S. Lindsay, John R. Petrie, Sandeep Thekkepat, Andrew Collier, Sandra MacRury, Helen M. Colhoun
Publikováno v:
BMC Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
Abstract Background The objective of this cross-sectional study was to explore the relationship of detectable C-peptide secretion in type 1 diabetes to clinical features and to the genetic architecture of diabetes. Methods C-peptide was measured in a
Externí odkaz:
https://doaj.org/article/65963f93a5364577a130f1dbc85bdfc6
Autor:
Helen M. Colhoun, Alan W. Patrick, Akram Asadi Shehni, Marco Colombo, Paul M. McKeigue, Andrew Collier, Stuart J. McGurnaghan, Hayden Wilkinson, Luke A K Blackbourn, Radka Saldova, John R. Petrie, Ioanna Thoma
Publikováno v:
Colombo, M, Shehni, A A, Thoma, I, Mcgurnaghan, S J, Blackbourn, L A K, Wilkinson, H, Collier, A, Patrick, A W, Petrie, J R, Mckeigue, P M, Saldova, R & Colhoun, H M 2020, ' Quantitative levels of serum N-glycans in type 1 diabetes and their association with kidney disease ', Glycobiology . https://doi.org/10.1093/glycob/cwaa106
We investigated associations of quantitative levels of N-glycans with hemoglobin A1c (HbA1c), renal function and renal function decline in type 1 diabetes. We measured 46 total N-glycan peaks (GPs) on 1565 serum samples from the Scottish Diabetes Res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de60e5c1ba815a7e2b14d5cb864dd78d
https://hdl.handle.net/20.500.11820/e2c5cab0-6443-42d6-bc57-bd1ead20d95e
https://hdl.handle.net/20.500.11820/e2c5cab0-6443-42d6-bc57-bd1ead20d95e
Autor:
Suna Onengut-Gomuscu, Timothy J. McDonald, Helen M. Colhoun, Stephen S. Rich, John R. Petrie, Alan W. Patrick, Colin N. A. Palmer, John A. McKnight, Luke A K Blackbourn, Mark W. J. Strachan, Andrew Collier, John Chalmers, Sandra MacRury, Athina Spiliopoulou, Robert S. Lindsay, Sandeep Thekkepat, Paul M. McKeigue, Marco Colombo, Stuart J. McGurnaghan
Publikováno v:
McKeigue, P M, Spiliopoulou, A, McGurnaghan, S, Colombo, M, Blackbourn, L, McDonald, T J, Onengut-Gumuscu, S, Rich, S S, Palmer, C N A, McKnight, J A, Strachan, M W J, Patrick, A W, Chalmers, J, Lindsay, R S, Petrie, J R, Thekkepat, S, Collier, A, MacRury, S & Colhoun, H M 2019, ' Persistent C-peptide secretion in Type 1 diabetes and its relationship to the genetic architecture of diabetes ', BMC Medicine, vol. 17, 165 . https://doi.org/10.1186/s12916-019-1392-8
BMC Medicine
BMC Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
BMC Medicine
BMC Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
Background The objective of this cross-sectional study was to explore the relationship of detectable C-peptide secretion in type 1 diabetes to clinical features and to the genetic architecture of diabetes. Methods C-peptide was measured in an untimed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b560582615e14df3f6811bf5ac6d90
https://hdl.handle.net/20.500.11820/34731b04-5d6c-4ee7-a2fd-ef16f22d066c
https://hdl.handle.net/20.500.11820/34731b04-5d6c-4ee7-a2fd-ef16f22d066c
Autor:
Samira Bell, John R. Petrie, Wendy Metcalfe, Finlay MacKenzie, Jamie P. Traynor, Stuart J. McGurnaghan, Alan W. Patrick, John A. McKnight, Marco Colombo, Paul M. McKeigue, Helen M. Colhoun, Sandra MacRury
Publikováno v:
Diabetologia
2020, ' Predicting renal disease progression in a large contemporary cohort with type 1 diabetes mellitus ', Diabetologia . https://doi.org/10.1007/s00125-019-05052-z
2020, ' Predicting renal disease progression in a large contemporary cohort with type 1 diabetes mellitus ', Diabetologia . https://doi.org/10.1007/s00125-019-05052-z
Aims/hypothesisThe aim of this study was to provide data from a contemporary population-representative cohort on rates and predictors of renal decline in type 1 diabetes.MethodsWe used data from a cohort of 5777 people with type 1 diabetes aged 16 an
Autor:
John A. McKnight, Sandeep Thekkepat, John Chalmers, Helen M. Colhoun, Stuart J. McGurnaghan, Alan W. Patrick, Anita Jeyam, Colin N. A. Palmer, Sandra MacRury, Paul M. McKeigue, Andrew Collier, Robert S. Lindsay, John R. Petrie, Luke A K Blackbourn, Timothy J. McDonald, Mark W. J. Strachan
Publikováno v:
Diabetes Care. :dc21er04b
The authors report that the following errors occurred in transcribing the results of the statistical computations into the abstract and text. In the Abstract, “insulin dose at …
Autor:
John A. McKnight, Frano Vučković, Helen M. Colhoun, Alan W. Patrick, Gordan Lauc, Paul M. McKeigue, Sandeep Thekkepat, Sandra MacRury, Andrew Collier, Olga Gornik, Anna Agakova, Stuart J. McGurnaghan, Fiona Green, John R. Petrie, Mairead L. Bermingham, Irena Trbojević-Akmačić, Felix Agakov, Marco Colombo, Caroline Hayward, Luke A K Blackbourn, Maja Pučić Baković, Lucija Klaric, John Chalmers, Robert S. Lindsay, Colin N. A. Palmer
Publikováno v:
2018, ' N-glycan Profile and Kidney Disease in Type 1 Diabetes ', Diabetes Care . https://doi.org/10.2337/dc17-1042
OBJECTIVE Poorer glycemic control in type 1 diabetes may alter N-glycosylation patterns on circulating glycoproteins, and these alterations may be linked with diabetic kidney disease (DKD). We investigated associations between N-glycans and glycemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859950b438b86d04786cb7bc8c1d1b0e
https://www.pure.ed.ac.uk/ws/files/45342602/SDRNT1BIO_N_Glycan_Paper_Diabetes_Care_2017R1.docx
https://www.pure.ed.ac.uk/ws/files/45342602/SDRNT1BIO_N_Glycan_Paper_Diabetes_Care_2017R1.docx
Autor:
Stephen L. Atkin, Geoff Beckett, Jyothi M Idiculla, James W. Ironside, Patrick Statham, Alan W. Patrick
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 38:566-571
A 44-year-old woman presented to her GP with excessive tiredness. She had positive thyroid microsomal and thyroglobulin autoantibodies and was found to have an elevated serum thyroid-stimulating hormone (TSH) concentration of 8.37 (normal = 0·15–3
Autor:
Robert S. Lindsay, Alan W. Patrick, John A. McKnight, Helen C. Looker, Stuart J. McGurnaghan, Shona Livingstone, Colin N. A. Palmer, Donald W. M. Pearson, Tahira Akbar, James D. Walker, John Chalmers, Helen M. Colhoun, John R. Petrie
Publikováno v:
International Journal of Epidemiology. :dyw152
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 40:295-297
Severe hypercalcaemia is usually due to either neoplastic disease or primary hyperparathyroidism. Rarer causes do exist, and exceptionally these may occur concomitantly. We describe the case of a 45-year-old man who presented in a debilitated state w