Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Alan W Heldman"'
Autor:
Angela C. Rieger, Robert J. Myerburg, Victoria Florea, Bryon A. Tompkins, Makoto Natsumeda, Courtney Premer, Aisha Khan, Ivonne H. Schulman, Mayra Vidro-Casiano, Darcy L. DiFede, Alan W. Heldman, Raul Mitrani, Joshua M. Hare
Publikováno v:
EBioMedicine, Vol 48, Iss , Pp 377-385 (2019)
Background: Non-ischemic dilated cardiomyopathy (NIDCM) responds variably to intramyocardial injection of mesenchymal stem cells (MSCs). We hypothesized that NIDCM genotype may influence responsiveness to MSC therapy and performed genotyping on all p
Externí odkaz:
https://doaj.org/article/01163b8467294193ba83ca5763e1cefa
Autor:
Victoria Florea, Angela C. Rieger, Alan W. Heldman, Makoto Natsumeda, Darcy L. DiFede, Aisha Khan, Mayra Vidro-Casiano, Raul Mitrani, Bryon A. Tompkins, Joshua M. Hare, Courtney Premer, Robert J. Myerburg, Ivonne Hernandez Schulman
Publikováno v:
EBioMedicine
EBioMedicine, Vol 48, Iss, Pp 377-385 (2019)
EBioMedicine, Vol 48, Iss, Pp 377-385 (2019)
Background: Non-ischemic dilated cardiomyopathy (NIDCM) responds variably to intramyocardial injection of mesenchymal stem cells (MSCs). We hypothesized that NIDCM genotype may influence responsiveness to MSC therapy and performed genotyping on all p
Autor:
Carlos Alfonso, Mauro Moscucci, Donald Williams, Mauricio G. Cohen, Julien Peltan, Alan W. Heldman, Seunghwan Byun, Abdulla A. Damluji, Lionel Leroux, Roger G. Carrillo, Peter W. Cho, Magdalena Murman, Christopher C. Kwon, Jon R. Resar, Marina Dijos, Rani K. Hasan
Publikováno v:
Catheterization and Cardiovascular Interventions. 92:1182-1193
BACKGROUND We examined the outcomes of older adults undergoing nontrans-femoral (non-TF) transcatheter aortic valve replacement (TAVR) procedures including trans-apical (TA), trans-aortic (TAo), trans-subclavian (TSub), and trans-carotid (TCa) techni
Autor:
Louis Vincent, Vasileios Karantalis, Kevin Collon, Raul Mitrani, Samuel Golpanian, Bryon A. Tompkins, Ana Marie Landin, Ariel Wolf, Monisha N. Banerjee, Cristina Sanina, Wayne Balkan, Alan W. Heldman, Makoto Natsumeda, Victoria Florea, Kostas E. Hatzistergos, Julia Fritsch, Nilesh D. Kashikar, Ivonne Hernandez Schulman, Angela C. Rieger, Viky Y. Loescher, Jose Rodriguez, Luiza Bagno, Muzammil Mushtaq, Marcos Rosado, Anthony J. Kanelidis, Joshua M. Hare
Publikováno v:
Journal of the American College of Cardiology. 70:2504-2515
Background The combination of autologous mesenchymal stem cells (MSCs) and cardiac stem cells (CSCs) synergistically reduces scar size and improves cardiac function in ischemic cardiomyopathy. Whereas allogeneic (allo-)MSCs are immunoevasive, the cap
Autor:
Darcy L. DiFede, Erica Anderson, Silvina Levis-Dusseau, Cindy Delgado, Joshua M. Hare, Russell G. Saltzman, Audrey Medina, Aisha Khan, Krystalenia Valasaki, Victoria Florea, Pascal J. Goldschmidt-Clermont, Makoto Natsumeda, Courtney Premer, Alan W. Heldman, Samuel Golpanian, Jill El-Khorazaty, Adam Mendizabal, John J. Byrnes, Mayra Vidro-Casiano, Anthony A. Oliva, Ana Marie Landin, Geoff Green, Ivonne Hernandez Schulman, Maureen H. Lowery, Moisaniel Da Fonseca, Marietsy V. Pujol, Muzammil Mushtaq, Roberto Miki, Bryon A. Tompkins, Bradley J. Goldstein
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Background Aging frailty, characterized by decreased physical and immunological functioning, is associated with stem cell depletion. Human allogeneic mesenchymal stem cells (allo-hMSCs) exert immunomodulatory effects and promote tissue repair. Method
Autor:
Joshua M. Hare, James O. Coffey, Chad Brodt, Chris Healy, Alan W. Heldman, Juan F. Viles-Gonzalez, Darcy L. DiFede, Archana Ramireddy, Adam Mendizabal, Yahya Alansari, Raul D. Mitrani, Jeffrey J. Goldberger, Robert J. Myerburg, Vishal Goyal
Publikováno v:
Stem Cells Translational Medicine
Transendocardial stem cell injection in patients with ischemic cardiomyopathy (ICM) improves left ventricular function and structure but has ill-defined effects on ventricular arrhythmias. We hypothesized that mesenchymal stem cell (MSC) implantation
Autor:
Samuel Golpanian, Robert C. Hendel, Ana Marie Landin, Audrey Medina, Krystalenia Valasaki, Joshua M. Hare, Valeria Porras, Raul Mitrani, Mauricio G. Cohen, Joel E. Fishman, Courtney Premer, Samirah A. Gomes, Jill El-Khorazaty, Adam Mendizabal, Maureen H. Lowery, Roberto Miki, Aisha Khan, Marietsy V. Pujol, Konstantinos E. Hatzistergos, Fouad Abuzeid, Eduard Ghersin, Angela C. Rieger, Erica Anderson, Cindy Delgado, Darcy L. DiFede, Alan W. Heldman, Pradip M. Pattany, Carlos Alfonso, John J. Byrnes, Mayra Vidro-Casiano, Victoria Florea, Muzammil Mushtaq
Publikováno v:
Journal of the American College of Cardiology. 69:526-537
Background Although human mesenchymal stem cells (hMSCs) have been tested in ischemic cardiomyopathy, few studies exist in chronic nonischemic dilated cardiomyopathy (NIDCM). Objectives The authors conducted a randomized comparison of safety and effi
Autor:
Alan W. Heldman, Vikas Singh, Carlos Alfonso, Rodrigo Mendirichaga, Abdulla A. Damluji, William W. O'Neill, Claudia Martinez, Eduardo de Marchena, Donald Williams, Mauricio G. Cohen
Publikováno v:
Journal of Interventional Cardiology. 29:513-522
Objective Evaluate the use of mechanical circulatory support (MCS) devices in high-risk patients undergoing transcatheter aortic valve replacement (TAVR). Background The use of MCS devices in elderly patients with multiple comorbidities undergoing TA
Autor:
Joshua M. Hare, Samuel Golpanian, Alan W. Heldman, Aisha Khan, Bangon Longsomboon, Silvina Levis-Dusseau, Maureen H. Lowery, Darcy L. DiFede, Pascal J. Goldschmidt-Clermont, Bradley J. Goldstein, Ivonne Hernandez Schulman, Ariel Wolf, Marietsy V. Pujol
Publikováno v:
Oncotarget
// Samuel Golpanian 1,2 , Darcy L. DiFede 1 , Marietsy V. Pujol 1 , Maureen H. Lowery 3 , Silvina Levis-Dusseau 3,5 , Bradley J. Goldstein 1,7 , Ivonne H. Schulman 1,3,6 , Bangon Longsomboon 1 , Ariel Wolf 1 , Aisha Khan 1 , Alan W. Heldman 1,3,4 , P
Autor:
Joshua M. Hare, Cristina Sanina, Vasileios Karantalis, Marcos Rosado, Samuel Golpanian, Muzammil Mushtaq, Anthony J. Kanelidis, Frederic McCall, Pradip M. Pattany, Darcy L. DiFede, Irene S. Margitich, Ariel Wolf, Bo Wang, Juan P. Zambrano, Courtney Premer, Ivonne Hernandez Schulman, Makoto Natsumeda, Wayne Balkan, Viky Y. Suncion-Loescher, Samirah A. Gomes, Jose Rodriguez, Luiza Bagno, Alan W. Heldman, Konstantinos E. Hatzistergos, Azorides R. Morales, Joel E. Fishman
Publikováno v:
Journal of the American College of Cardiology. 66(18):1990-1999
Both bone marrow-derived mesenchymal stem cells (MSCs) and c-kit(+) cardiac stem cells (CSCs) improve left ventricular remodeling in porcine models and clinical trials. Using xenogeneic (human) cells in immunosuppressed animals with acute ischemic he