Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Alan W, Schwabacher"'
MppQ is an enzyme of unknown function from Streptomyces hygroscopicus that is involved in the biosynthesis of the nonproteinogenic amino acid L-enduracididine (L-End). Since L-End is a component of several peptides showing high activity against methi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e0f1370d00fc4025512d72316444a67
https://doi.org/10.1101/2022.04.03.486910
https://doi.org/10.1101/2022.04.03.486910
Publikováno v:
Biochemistry. 58:4136-4147
The acetoacetate decarboxylase-like superfamily (ADCSF) is a little-explored group of enzymes that may contain new biocatalysts. The low level of sequence identity (∼20%) between many ADCSF enzymes and the confirmed acetoacetate decarboxylases led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1efa9a7a9a2d73c128463ef79d58f4b0
https://doi.org/10.1021/acs.biochem.9b00652
https://doi.org/10.1021/acs.biochem.9b00652
Autor:
T. William Knight, Zahra Mashhadi, Alan W. Schwabacher, Robert W. Hoppe, Hagemann Trevor, Lisa S. Mydy, Todd R. Miller, Tyler Grant Fenske, Lanlan Han, Nicholas R. Silvaggi
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 73:672-681
The Gram-negative bacterium Sphingomonas wittichii RW1 is notable for its ability to metabolize a variety of aromatic hydrocarbons. Not surprisingly, the S. wittichii genome contains a number of putative aromatic hydrocarbon-degrading gene clusters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56740b597f918f4a11f883a175ac631e
https://doi.org/10.1107/s2053230x17015862
https://doi.org/10.1107/s2053230x17015862
Publikováno v:
Biochemistry. 58(40)
The acetoacetate decarboxylase-like superfamily (ADCSF) is a little-explored group of enzymes that may contain new biocatalysts. The low level of sequence identity (∼20%) between many ADCSF enzymes and the confirmed acetoacetate decarboxylases led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::454f35ace2f6c6d0b225e339fed7419e
https://pubmed.ncbi.nlm.nih.gov/31790220
https://pubmed.ncbi.nlm.nih.gov/31790220
Publikováno v:
Organic Letters. 18:4174-4177
An enolate driven copper-mediated cross-coupling process enabled a cheaper and greener access toward the key pentacyclic intermediates required for the enantiospecific total synthesis of a number of C-19 methyl substituted sarpagine/macroline indole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1876fe94124dde9d93e88e5b1f5bc8bb
https://doi.org/10.1021/acs.orglett.6b01526
https://doi.org/10.1021/acs.orglett.6b01526
Publikováno v:
Biochemistry. 58:5022-5022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cfd1e98bc3eeb22d90ffd215e74899a
https://doi.org/10.1021/acs.biochem.9b00984
https://doi.org/10.1021/acs.biochem.9b00984
Autor:
Alan W. Schwabacher, Nicholas R. Silvaggi, Nemanja Vuksanovic, Lanlan Han, Sarah Oehm, Tyler Grant Fenske
Publikováno v:
Biochemistry. 58:5023-5023
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df6bf01be26b1e302ed46d958cc91bba
https://doi.org/10.1021/acs.biochem.9b00994
https://doi.org/10.1021/acs.biochem.9b00994
Autor:
Tyler Grant Fenske, Sarah Oehm, Nicholas R. Silvaggi, Alan W. Schwabacher, Nemanja Vuksanovic, Lanlan Han
Publikováno v:
Biochemistry. 57(23)
The PLP-dependent l-arginine hydroxylase/deaminase MppP from Streptomyces wadayamensis (SwMppP) is involved in the biosynthesis of l-enduracididine, a nonproteinogenic amino acid found in several nonribosomally produced peptide antibiotics. SwMppP us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f32665b00fd671dd7f8b5af010221b
https://pubmed.ncbi.nlm.nih.gov/31790219
https://pubmed.ncbi.nlm.nih.gov/31790219
Autor:
Alan W. Schwabacher, Nicholas R. Silvaggi, Tyler J. Voegtline, Bilal H. Sayyed, Robert W. Hoppe, Neal C. Goebel, A. Maxwell Burroughs, T. Mark Zabriskie
Publikováno v:
Biochemistry. 52:4492-4506
The non-proteinogenic amino acid enduracididine is a critical component of the mannopeptimycins, cyclic glycopeptide antibiotics with activity against drug-resistant pathogens including methicillin-resistant Staphylococcus aureus. Enduracididine is p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de50779f016a867bd55a01a94ebc72ed
https://doi.org/10.1021/bi400397k
https://doi.org/10.1021/bi400397k
Publikováno v:
Biochemistry. 54(47)
L-Enduracididine (L-End) is a nonproteinogenic amino acid found in a number of bioactive peptides, including the antibiotics teixobactin, enduracidin, and mannopeptimycin. The potent activity of these compounds against antibiotic-resistant pathogens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1062762502d1a2b49c0f1a212038adb
https://pubmed.ncbi.nlm.nih.gov/26551990
https://pubmed.ncbi.nlm.nih.gov/26551990