Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Alan V. Boddy"'
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2020)
Long-term use of imatinib is effective and well-tolerated in children with chronic myeloid leukaemia (CML) yet defining an optimal dosing regimen for imatinib in younger patients is a challenge. The potential interactions between imatinib and coadmin
Externí odkaz:
https://doaj.org/article/3dd3254fa2494be99163bc2d7cfe3279
Autor:
Anthony Oxley, Philip Berry, Gordon A. Taylor, Joseph Cowell, Michael J. Hall, John Hesketh, Georg Lietz, Alan V. Boddy
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 2, Pp 319-328 (2014)
Isotope dilution is currently the most accurate technique in humans to determine vitamin A status and bioavailability/bioconversion of provitamin A carotenoids such as β-carotene. However, limits of MS detection, coupled with extensive isolation pro
Externí odkaz:
https://doaj.org/article/1e5c8203a3e44402be9274d6acb67c14
Autor:
Wai-Jo Jocelin Chan, Jeffry Adiwidjaja, Andrew J. McLachlan, Alan V. Boddy, Joanna E. Harnett
Publikováno v:
Cancer Chemotherapy and Pharmacology. 91:103-119
Natural products, also referred to as dietary supplements, complementary and alternative medicines, and health or food supplements are widely used by people living with cancer. These products are predominantly self-selected and taken concurrently wit
Autor:
Jann N. Sarkaria, William F. Elmquist, Nicola J. Curtin, Nathalie Y.R. Agar, Alan V. Boddy, Julieann Sludden, Mark A. Schroeder, Brett L. Carlson, Rajendar K. Mittapalli, Sani Kizilbash, David Calligaris, James Murray, Ling Cen, Karen E. Parrish
Supplemental Figure 1. MALDI FTICR mass spectra selected from a pixel with maximum intensity in the MS images of liver (A) and flank tumor (B) sections showing the two first isotopes of rucaparib (peaks labelled 1 and 2, respectively). (C) MALDI FTIC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1129c787b2292e6df7e3ef3694a32e7c
https://doi.org/10.1158/1535-7163.22503525.v1
https://doi.org/10.1158/1535-7163.22503525.v1
Autor:
Darren Hargrave, Murray Yule, Melanie J. Griffin, Alan V. Boddy, John F. Lyons, Ana Rodriguez, Victoria Lock, Shamim Kazmi-Stokes, Philip Ross, Gary Acton, Sarah E.R. Halford, Guy Makin, Quentin Campbell-Hewson, Martin Elliott, Bruce Morland, Andrew D.J. Pearson, Lynley V. Marshall, Lucas Moreno
Supplementary Figure 1. Examples of changes observed in M30/M65 profiles as a function of dosing of AT9283 in two selected patients. Pt. 58/032 from cohort 4 (14.5 mg/m2/day) and Pt. 31/030 from cohort 6 (23 mg/m2/day).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecad42031facf935942fc7b688af840e
https://doi.org/10.1158/1078-0432.22460577.v1
https://doi.org/10.1158/1078-0432.22460577.v1
Autor:
Steven C. Clifford, Nicola J. Curtin, Deborah A. Tweddle, Alan V. Boddy, E. Ruth Plummer, Zdenek Hostomsky, Deborah J. Castelbuono, Yvette Drew, Evan A. Mulligan, Huw D. Thomas, Agata L. Rozanska, Rachel A. Daniel
Purpose: High-risk neuroblastoma is characterized by poor survival rates, and the development of improved therapeutic approaches is a priority. Temozolomide and topotecan show promising clinical activity against neuroblastoma. Poly(ADP-ribose) polyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689bae8a42187edf2016b2eb79d8a34f
https://doi.org/10.1158/1078-0432.c.6517512
https://doi.org/10.1158/1078-0432.c.6517512
Autor:
Alan V. Boddy, Andrew D.J. Pearson, Ann K. Daly, Michael Cole, Ghada Malik, Nicola A. Illingworth, Sophie E. Rowbotham, Julie Errington, Gareth J. Veal
PDF file - 72K, Observed and fitted 13-cisRA data from four patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4e2bc41b377f2d8d1a9ee8a3826532
https://doi.org/10.1158/1078-0432.22455344.v1
https://doi.org/10.1158/1078-0432.22455344.v1
Autor:
Steven C. Clifford, Nicola J. Curtin, Deborah A. Tweddle, Alan V. Boddy, E. Ruth Plummer, Zdenek Hostomsky, Deborah J. Castelbuono, Yvette Drew, Evan A. Mulligan, Huw D. Thomas, Agata L. Rozanska, Rachel A. Daniel
Supplementary Data from Inhibition of Poly(ADP-Ribose) Polymerase-1 Enhances Temozolomide and Topotecan Activity against Childhood Neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::591ee30bf0243646e9054a29e642993b
https://doi.org/10.1158/1078-0432.22440144
https://doi.org/10.1158/1078-0432.22440144
Autor:
Alan V. Boddy, Andrew D.J. Pearson, Ann K. Daly, Michael Cole, Ghada Malik, Nicola A. Illingworth, Sophie E. Rowbotham, Julie Errington, Gareth J. Veal
PDF file - 43K, Relationship between 13-cisRA AUC0-6h and 13-cisRA Cmax determined from pharmacokinetic profiles obtained following protocol-based 13-cisRA dosing (n=103)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ed9912ffabfaae1260fd952fa157e2
https://doi.org/10.1158/1078-0432.22455341
https://doi.org/10.1158/1078-0432.22455341
Autor:
Alan V. Boddy, Andrew D.J. Pearson, Ann K. Daly, Michael Cole, Ghada Malik, Nicola A. Illingworth, Sophie E. Rowbotham, Julie Errington, Gareth J. Veal
PDF file - 46K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c1c13e553d08bc50f6ca756690f615
https://doi.org/10.1158/1078-0432.22455338
https://doi.org/10.1158/1078-0432.22455338