Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alan Tunnicliffe"'
Autor:
Patrizia Mecocci, Abdul Hye, Richard Dobson, Michelle K. Lupton, Iwona Kłoszewska, Hans Dieter Zucht, Danielle Pepin, Bruno Vellas, Nicholas J. Ashton, Eric Westman, Jill C. Richardson, Chantal Bazenet, Wei Zheng, Alan Tunnicliffe, Hilkka Soininen, Ian Pike, Alison L. Baird, Malcolm Ward, Simon Lovestone, Magda Tsolaki, Katie Lunnon, Rufina Leung, Andrew Simmons, Joanna Riddoch-Contreras, Serge Gauthier, Martina Sattlecker, Aoife Keohane
Publikováno v:
Hye, A, Riddoch-Contreras, J, Baird, A L, Ashton, N, Bazenet, C, Leung, R, Westman, E, Simmons, A, Dobson, R, Sattlecker, M, Lupton, M, Lunnon, K, Keohane, A, Ward, M, Pike, I, Zucht, H D, Pepin, D, Zheng, W, Tunnicliffe, A, Richardson, J, Gauthier, S, Soininen, H, Kłoszewska, I, Mecocci, P, Tsolaki, M, Vellas, B & Lovestone, S 2014, ' Plasma proteins predict conversion to dementia from prodromal disease ', Alzheimers & Dementia, vol. 10, no. 6, pp. 799–807.e2 . https://doi.org/10.1016/j.jalz.2014.05.1749
BackgroundThe study aimed to validate previously discovered plasma biomarkers associated with AD, using a design based on imaging measures as surrogate for disease severity and assess their prognostic value in predicting conversion to dementia.Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84a146f78f8a840f6a3b536a135d1dc
https://kclpure.kcl.ac.uk/ws/files/148421887/j.jalz.2014.05.1749.pdf
https://kclpure.kcl.ac.uk/ws/files/148421887/j.jalz.2014.05.1749.pdf
Autor:
Gina Rosenbrock, Simon A. Weston, Ian W. F. Taylor, Richard A. Pauptit, Peter T. Barth, Alan Tunnicliffe, Geoffrey A. Holdgate, Walter H.J. Ward, David Timms
Publikováno v:
Biochemistry. 36:9663-9673
Novobiocin is an antibiotic which binds to a 24 kDa fragment from the B subunit of DNA gyrase. Naturally occurring resistance arises from mutation of Arg-136 which hydrogen bonds to the coumarin ring of novobiocin. We have applied calorimetry to char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::badf191133124286fdcf153354d635fe
https://doi.org/10.1021/bi970294+
https://doi.org/10.1021/bi970294+
Autor:
Eric de La Fortelle, Mark Egerton, Gérard Bricogne, John J. Irwin, Roger Camble, Richard A. Pauptit, Ian W. F. Taylor, Alan Tunnicliffe, Alec D. Tucker, Anil Mistry, Filippo Mancia, Simon A. Weston, Jeremy G. Colls, Gina Rosenbrock
Publikováno v:
Nature structural biology. 5(3)
N-myristoyl transferase (NMT) catalyzes the transfer of the fatty acid myristate from myristoyl-CoA to the N-terminal glycine of substrate proteins, and is found only in eukaryotic cells. The enzyme in this study is the 451 amino acid protein produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2d10fdbe4ec1e27219cc7ffd88fe18
https://pubmed.ncbi.nlm.nih.gov/9501915
https://pubmed.ncbi.nlm.nih.gov/9501915