Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Alan Tessler"'
Publikováno v:
Experimental Neurobiology
Injured primary sensory axons fail to regenerate into the spinal cord, leading to chronic pain and permanent sensory loss. Re-entry is prevented at the dorsal root entry zone (DREZ), the CNS-PNS interface. Why axons stop or turn around at the DREZ ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d8510872c98a000ecb5eedd278f930
https://doi.org/10.5607/en.2012.21.3.83
https://doi.org/10.5607/en.2012.21.3.83
Publikováno v:
Journal of Neurotrauma. 28:547-563
Concussive brain injury (CBI) accounts for approximately 75% of all brain-injured people in the United States each year and is particularly prevalent in contact sports. Concussion is the mildest form of diffuse traumatic brain injury (TBI) and result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1d2954d9ba5e49383ebab868203426
https://doi.org/10.1089/neu.2010.1729
https://doi.org/10.1089/neu.2010.1729
Publikováno v:
Journal of Applied Physiology. 107:1190-1194
Current evidence suggests that significant morphological changes occur in nerve-muscle connections caudal to spinal cord injury (SCI). To determine whether neuromuscular junction (NMJ) function is compromised after SCI, we investigated the contributi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4e21bd1a2a9c88ce31ccf11e9983e5
https://doi.org/10.1152/japplphysiol.00282.2009
https://doi.org/10.1152/japplphysiol.00282.2009
Autor:
B. Timothy Himes, Alan Tessler, Kook In Park, Itzhak Fischer, Evan Y. Snyder, Philip E. Stieg
Publikováno v:
Experimental Neurology. 199:179-190
Previously, we reported that, when clonal neural stem cells (NSCs) were transplanted into brains of postnatal mice subjected to unilateral hypoxic-ischemic (HI) injury (optimally 3-7 days following infarction), donor-derived cells homed preferentiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f0eeba2b36eb86bae8de95e07c3d67
https://doi.org/10.1016/j.expneurol.2006.03.016
https://doi.org/10.1016/j.expneurol.2006.03.016
Autor:
Srishti Bhagat, Sabiha Jawaid, Anthony S. Burns, Young-Jin Son, Alan Tessler, Hui Zhong, Marion Murray, Hiroyuki Yoshihara, Roland R. Roy
Publikováno v:
The Journal of Comparative Neurology. 500:116-133
Neuromuscular junctions (NMJs) innervated by motor neurons below spinal cord injury (SCI) have been reported to remain intact despite the interruption of supraspinal pathways and the resultant loss of activity. Here we report notably heterogeneous NM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eca62adff706389e04494b2d962b33c
https://doi.org/10.1002/cne.21143
https://doi.org/10.1002/cne.21143
Publikováno v:
Journal of Neurotrauma. 21:405-413
In this review we consider recovery of function after spinal cord injury, and, in particular, recovery improved following intraspinal cellular transplants. Some recovery occurs spontaneously and this can be especially dramatic in neonates, supporting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80982e890da19a466f2e4434c0e2cb3
https://doi.org/10.1089/089771504323004557
https://doi.org/10.1089/089771504323004557
Autor:
Mark H. Tuszynski, Alan Tessler, M Shibata, C.A Tobias, Jed S. Shumsky, Marion Murray, Itzhak Fischer
Publikováno v:
Experimental Neurology. 184:97-113
Ex vivo gene therapy, utilizing modified fibroblasts that deliver BDNF or NT-3 to the acutely injured spinal cord, has been shown to elicit regeneration and recovery of function in the adult rat. Delayed grafting into the injured spinal cord is of gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f68a57cb64dae75126dd7ca225b2271
https://doi.org/10.1016/s0014-4886(03)00394-7
https://doi.org/10.1016/s0014-4886(03)00394-7
Autor:
Alan Tessler, John D Houle
Publikováno v:
Experimental Neurology. 182:247-260
Advances in medical and rehabilitative care now allow the 10-12,000 individuals who suffer spinal cord injuries each year in the United States to lead productive lives of nearly normal life expectancy, so that the numbers of those with chronic injuri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337846d56958b04988cf2929e2aa5c27
https://doi.org/10.1016/s0014-4886(03)00029-3
https://doi.org/10.1016/s0014-4886(03)00029-3
Publikováno v:
Neurorehabilitation and Neural Repair. 15:173-182
Objective: The purpose of this study was to determine whether glial cell line—de rived neurotrophic factor (GDNF) delivered intraspinally via a fibrin glue (FG) en hanced regeneration of cut dorsal root (DR). Methods: FG containing GDNF was inserte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060a6066586fef3181a7e6f2c9b1c6bd
https://doi.org/10.1177/154596830101500304
https://doi.org/10.1177/154596830101500304
Autor:
Itzhak Fischer, Yi Liu, Alan Tessler, S. Y. Chow, L. Hodge, B. T. Himes, J. Moul, Maria Obrocka, C.A Tobias
Publikováno v:
Brain Research. 874:87-106
Recent advances in the isolation and characterization of neural precursor cells suggest that they have properties that would make them useful transplants for the treatment of central nervous system disorders. We demonstrate here that spinal cord cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334a0970956de687dbd1edeb69e807bf
https://doi.org/10.1016/s0006-8993(00)02443-4
https://doi.org/10.1016/s0006-8993(00)02443-4