Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Alan T. Yeo"'
Autor:
Hyun Jung Jun, Vicky A. Appleman, Hua-Jun Wu, Christopher M. Rose, Javier J. Pineda, Alan T. Yeo, Bethany Delcuze, Charlotte Lee, Aron Gyuris, Haihao Zhu, Steve Woolfenden, Agnieszka Bronisz, Ichiro Nakano, Ennio A. Chiocca, Roderick T. Bronson, Keith L. Ligon, Jann N. Sarkaria, Steve P. Gygi, Franziska Michor, Timothy J. Mitchison, Al Charest
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Amplification of PDGFRα is a common alteration in glioblastoma. In this study, the authors develop a genetically engineered mouse model of GBM based on autocrine, chronic stimulation of overexpressed PDGFR and discover Stathmin1 as an important PDGF
Externí odkaz:
https://doaj.org/article/e36e588f60e24fb6aa72e07d8947fc7d
Publikováno v:
Molecules, Vol 20, Iss 5, Pp 7474-7494 (2015)
Increased activity of transcription factor NF-κB has been implicated in many B-cell lymphomas. We investigated effects of synthetic compound calafianin monomer (CM101) on biochemical and biological properties of NF-κB. In human 293 cells, CM101 sel
Externí odkaz:
https://doaj.org/article/8bd30e9e7bd74f589588ea5a33912c2d
Autor:
Al Charest, Vassiliki A. Boussiotis, Roel G.W. Verhaak, Steven P. Gygi, Hemant Varma, Joon Yoon, Vicky A. Appleman, Frederick S. Varn, Christopher M. Rose, Shruti Rawal, Piyan Zhang, Tuoye Xu, Rinku Pal, Konstantinos Aliazis, Rushil Shah, Alan T. Yeo
supplementary figures & legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70022129900a397dd403b1e4e220bf3a
https://doi.org/10.1158/2326-6066.22736977.v1
https://doi.org/10.1158/2326-6066.22736977.v1
Autor:
Al Charest, Vassiliki A. Boussiotis, Roel G.W. Verhaak, Steven P. Gygi, Hemant Varma, Joon Yoon, Vicky A. Appleman, Frederick S. Varn, Christopher M. Rose, Shruti Rawal, Piyan Zhang, Tuoye Xu, Rinku Pal, Konstantinos Aliazis, Rushil Shah, Alan T. Yeo
The composition of the tumor immune microenvironment (TIME) is considered a key determinant of patients’ response to immunotherapy. The mechanisms underlying TIME formation and development over time are poorly understood. Glioblastoma (GBM) is a le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::543faa9205d3847638c4473786e3c891
https://doi.org/10.1158/2326-6066.c.6597334
https://doi.org/10.1158/2326-6066.c.6597334
Autor:
Al Charest, Vassiliki A. Boussiotis, Roel G.W. Verhaak, Steven P. Gygi, Hemant Varma, Joon Yoon, Vicky A. Appleman, Frederick S. Varn, Christopher M. Rose, Shruti Rawal, Piyan Zhang, Tuoye Xu, Rinku Pal, Konstantinos Aliazis, Rushil Shah, Alan T. Yeo
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a623268b28b605e25745907cdd3d1d06
https://doi.org/10.1158/2326-6066.22736980.v1
https://doi.org/10.1158/2326-6066.22736980.v1
Autor:
Alan T. Yeo, Rushil Shah, Konstantinos Aliazis, Rinku Pal, Tuoye Xu, Piyan Zhang, Shruti Rawal, Christopher M. Rose, Frederick S. Varn, Vicky A. Appleman, Joon Yoon, Hemant Varma, Steven P. Gygi, Roel G.W. Verhaak, Vassiliki A. Boussiotis, Al Charest
Publikováno v:
Yeo, A T, Shah, R, Aliazis, K, Pal, R, Xu, T, Zhang, P, Rawal, S, Rose, C M, Varn, F S, Appleman, V A, Yoon, J, Varma, H, Gygi, S P, Verhaak, R G W, Boussiotis, V A & Charest, A 2023, ' Driver Mutations Dictate the Immunologic Landscape and Response to Checkpoint Immunotherapy of Glioblastoma ', Cancer Immunology Research, vol. 11, no. 5, pp. 629-645 . https://doi.org/10.1158/2326-6066.CIR-22-0655
Cancer Immunology Research, 11(5), 629-645. American Association for Cancer Research Inc.
Cancer Immunology Research, 11(5), 629-645. American Association for Cancer Research Inc.
The composition of the tumor immune microenvironment (TIME) is considered a key determinant of patients’ response to immunotherapy. The mechanisms underlying TIME formation and development over time are poorly understood. Glioblastoma (GBM) is a le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6417b788e05ae4916b1d2a24ee5a1ea1
https://research.vumc.nl/en/publications/8e8c49cb-4b3e-468f-9b8a-b6372f23f01e
https://research.vumc.nl/en/publications/8e8c49cb-4b3e-468f-9b8a-b6372f23f01e
Autor:
Jeffrey A. Engelman, Cyril H. Benes, Kenneth E. Hung, Sridhar Ramaswamy, Miguel N. Rivera, Ryan B. Corcoran, Rakesh K. Jain, David P. Kodack, Jatin Roper, Randy J. Milano, Jessica L. Boisvert, Ah Ting Tam, Youngchul Song, Elena J. Edelman, Alan T. Yeo, Aaron N. Hata, Hiromichi Ebi, Anahita Dastur, Carlotta Costa, Erin M. Coffee, Anthony C. Faber
PDF file140K, Supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045c843e45fbd2b4161c4a2d2272bc8c
https://doi.org/10.1158/2159-8290.22530782
https://doi.org/10.1158/2159-8290.22530782
Autor:
Jeffrey A. Engelman, Cyril H. Benes, Kenneth E. Hung, Sridhar Ramaswamy, Miguel N. Rivera, Ryan B. Corcoran, Rakesh K. Jain, David P. Kodack, Jatin Roper, Randy J. Milano, Jessica L. Boisvert, Ah Ting Tam, Youngchul Song, Elena J. Edelman, Alan T. Yeo, Aaron N. Hata, Hiromichi Ebi, Anahita Dastur, Carlotta Costa, Erin M. Coffee, Anthony C. Faber
PDF file 764K, Supp. Figures 1-10 include data describing in vitro and in vivo experiments in support of Faber at al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524b180d84ebc661d7c1f2bb2eb52a76
https://doi.org/10.1158/2159-8290.22530785.v1
https://doi.org/10.1158/2159-8290.22530785.v1
Autor:
Ronnie Alterman, Al Charest, Nancy Hsu, Barbara Vidal, Hemant Varma, Alan T. Yeo, Christine R. Bryke
Publikováno v:
Clinical Neuropathology. 39:126-134
The molecular alterations underlying progression of low-grade glial/glioneuronal tumors remain to be elucidated. We present a case of a 56-year-old male with an enhancing left temporal lobe tumor. Histology revealed a high-grade glioma adjacent to a
Autor:
Alan T. Yeo, Shruti Rawal, Bethany Delcuze, Anthos Christofides, Agata Atayde, Laura Strauss, Leonora Balaj, Vaughn A. Rogers, Erik J. Uhlmann, Hemant Varma, Bob S. Carter, Vassiliki A. Boussiotis, Al Charest
Publikováno v:
Nature immunology. 23(6)
Glioblastoma (GBM) is an incurable primary malignant brain cancer hallmarked with a substantial protumorigenic immune component. Knowledge of the GBM immune microenvironment during tumor evolution and standard of care treatments is limited. Using sin