Zobrazeno 1 - 10
of 667
pro vyhledávání: '"Alan T, Remaley"'
Publikováno v:
Cardiology and Therapy, Vol 13, Iss 3, Pp 465-491 (2024)
Abstract Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of morbidity and mortality despite effective low-density lipoprotein cholesterol-targeted therapies. This review explores the crucial role of inflammation in the residual
Externí odkaz:
https://doaj.org/article/3454fbe2fc964ea2b65c4281997971a5
Autor:
Reyna Lam, Sheila M. Manemann, Kristina E. Seehusen, Alan T. Remaley, Jennifer L. St. Sauver, Ruoxiang Jiang, Jill M. Killian, Maureen Sampson, Jeffrey W. Meeusen, Paul A. Decker, Véronique L. Roger, Paul Y. Takahashi, Nicholas B. Larson, Suzette J. Bielinski
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Background Low-density lipoprotein cholesterol (LDL-C) is associated with atherosclerotic cardiovascular disease (ASCVD). Friedewald, Sampson, and Martin-Hopkins equations are used to calculate LDL-C. This study compares the impact of switch
Externí odkaz:
https://doaj.org/article/48fb9cd7e7354e49b02a66a07c29c217
Autor:
Anna Wolska, Maureen Sampson, Rafael Zubirán, Jeff W. Meeusen, Leslie J. Donato, Allan S. Jaffe, Alan T. Remaley
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundThe triglyceride (TG) content of low-density lipoprotein (LDL-TG) has been shown to be more predictive of atherosclerotic cardiovascular disease (ASCVD) events than the cholesterol content of LDL (LDL-C). The goal of our study was to develo
Externí odkaz:
https://doaj.org/article/2334aa198b154c47ac13d4b86c56a1af
Autor:
Tatiana C. Coverdell, Maureen Sampson, Rafael Zubirán, Anna Wolska, Leslie J. Donato, Jeff W. Meeusen, Allan S. Jaffe, Alan T. Remaley
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background The accurate measurement of Low-density lipoprotein cholesterol (LDL-C) is critical in the decision to utilize the new lipid-lowering therapies like PCSK9-inhibitors (PCSK9i) for high-risk cardiovascular disease patients that do n
Externí odkaz:
https://doaj.org/article/7403eba74a3b4bc1aba9f686e7990b06
Autor:
Sant Kumar, Katherine M. Conners, Joseph J. Shearer, Jungnam Joo, Sarah Turecamo, Maureen Sampson, Anna Wolska, Alan T. Remaley, Margery A. Connelly, James D. Otvos, Nicholas B. Larson, Suzette J. Bielinski, Véronique L. Roger
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 8 (2024)
Background Frailty is common in heart failure (HF) and is associated with death but not routinely captured clinically. Frailty is linked with inflammation and malnutrition, which can be assessed by a novel plasma multimarker score: the metabolic vuln
Externí odkaz:
https://doaj.org/article/a7804c95517543f4979d503539466b34
Autor:
Kristina E. Seehusen, Alan T. Remaley, Maureen Sampson, Jeffrey W. Meeusen, Nicholas B. Larson, Paul A. Decker, Jill M. Killian, Paul Y. Takahashi, Véronique L. Roger, Sheila M. Manemann, Reyna Lam, Suzette J. Bielinski
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 8 (2024)
Background Clinical risk scores are used to identify those at high risk of atherosclerotic cardiovascular disease (ASCVD). Despite preventative efforts, residual risk remains for many individuals. Very low‐density lipoprotein cholesterol (VLDL‐C)
Externí odkaz:
https://doaj.org/article/2c8bc9eb6c194bcfa5591f694f21113b
Autor:
Bryce Chackerian, Alan T. Remaley
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 3, Pp 100524- (2024)
Externí odkaz:
https://doaj.org/article/14c99cc03e3c4637937d96018bc4007f
Autor:
Yuki Takechi-Haraya, Takashi Ohgita, Akiko Usui, Kazuchika Nishitsuji, Kenji Uchimura, Yasuhiro Abe, Ryuji Kawano, Monika I. Konaklieva, Mart Reimund, Alan T. Remaley, Yoji Sato, Ken-ichi Izutsu, Hiroyuki Saito
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Amphipathic arginine-rich peptide, A2-17, exhibits moderate perturbation of lipid membranes and the highest cell penetration among its structural isomers. We investigated the direct cell-membrane penetration mechanism of the A2-17 peptide wh
Externí odkaz:
https://doaj.org/article/b8893099f948499b954ee0db0b116037
Autor:
Alexandra Fowler, Koen K. A. Van Rompay, Maureen Sampson, Javier Leo, Jennifer K. Watanabe, Jodie L. Usachenko, Ramya Immareddy, Debbie M. Lovato, John T. Schiller, Alan T. Remaley, Bryce Chackerian
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract Elevated low-density lipoprotein cholesterol (LDL-C) is an important risk factor in the development of atherosclerotic cardiovascular disease (ASCVD). Inhibitors of proprotein convertase subtilisin/kexin type 9 (PCSK9), a negative regulator
Externí odkaz:
https://doaj.org/article/facb55d5a57b495fafe7c6f7e035a99f
Autor:
Hiroaki Kikuchi, Chung-Lin Chou, Chin-Rang Yang, Lihe Chen, Hyun Jun Jung, Euijung Park, Kavee Limbutara, Benjamin Carter, Zhi-Hong Yang, Julia F. Kun, Alan T. Remaley, Mark A. Knepper
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Loss of a kidney results in compensatory growth of the remaining kidney, a phenomenon of considerable clinical importance. However, the mechanisms involved are largely unknown. Here, we use a multi-omic approach in a unilateral nephrectomy m
Externí odkaz:
https://doaj.org/article/b78ed78be7ec4a53a693eb87505d12fc