Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Alan Soo Beng Khoo"'
Autor:
Joyce Siew Yong Low, Yoon Ming Chin, Taisei Mushiroda, Michiaki Kubo, Gopala Krishnan Govindasamy, Kin Choo Pua, Yoke Yeow Yap, Lee Fah Yap, Selva Kumar Subramaniam, Cheng Ai Ong, Tee Yong Tan, Alan Soo Beng Khoo, Malaysian NPC Study Group, Ching Ching Ng
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145774 (2016)
BACKGROUND:Nasopharyngeal carcinoma (NPC) is a neoplasm of the epithelial lining of the nasopharynx. Despite various reports linking genomic variants to NPC predisposition, very few reports were done on copy number variations (CNV). CNV is an inheren
Externí odkaz:
https://doaj.org/article/8e7fa5cd0c6740c49c419f65ce18740c
Autor:
Xiao-Yu Zuo, Qi-Sheng Feng, Jian Sun, Pan-Pan Wei, Yoon-Ming Chin, Yun-Miao Guo, Yun-Fei Xia, Bo Li, Xiao-Jun Xia, Wei-Hua Jia, Jian-Jun Liu, Alan Soo-Beng Khoo, Taisei Mushiroda, Ching-Ching Ng, Wen-Hui Su, Yi-Xin Zeng, Jin-Xin Bei
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-11 (2019)
Abstract Background The male predominance in the incidence of nasopharyngeal carcinoma (NPC) suggests the contribution of the X chromosome to the susceptibility of NPC. However, no X-linked susceptibility loci have been examined by genome-wide associ
Externí odkaz:
https://doaj.org/article/38e8451dc36b44588032740922b7d6f0
Publikováno v:
Human Genomics, Vol 12, Iss 1, Pp 1-21 (2018)
Abstract Background The mechanism underlying chromosome rearrangement in nasopharyngeal carcinoma (NPC) remains elusive. It is known that most of the aetiological factors of NPC trigger oxidative stress. Oxidative stress is a potent apoptotic inducer
Externí odkaz:
https://doaj.org/article/d16c553c48554608a7650d6728b62aa5
Autor:
Allan Hildesheim, Yi-Xin Zeng, Jian-Jun Liu, Gang-Qiao Zhou, Hongxin Zhang, Yun-Fei Xia, Ka-Po Tse, Soo-Hwang Teo, Kin-Choo Pua, Hao-Yuan Mo, Wen-Sheng Liu, Alan Soo-Beng Khoo, Wei-Hua Jia, Yun-Miao Guo, Qi-Shen Feng, Fu-Tuo Feng, Qian Cui, Ming-Yuan Chen, Li-Zhen Chen, Yu-Sun Chang, Chien-Jen Chen, James D. McKay, Wan-Lun Hsu, Pei-Jen Lou, Yoon-Ming Chin, Kai Yu, Ching-Ching Ng, Wen-Hui Su, Jin-Xin Bei
Supplemental Table 1S. Sequenome Primer Design for 43 SNPs included in Our Replications Studies. Supplemental Table 2S. Results from NPC GWAS Meta-Analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f92857be4594d41c9818f0ae9a5c0b
https://doi.org/10.1158/1055-9965.22437970
https://doi.org/10.1158/1055-9965.22437970
Autor:
Allan Hildesheim, Yi-Xin Zeng, Jian-Jun Liu, Gang-Qiao Zhou, Hongxin Zhang, Yun-Fei Xia, Ka-Po Tse, Soo-Hwang Teo, Kin-Choo Pua, Hao-Yuan Mo, Wen-Sheng Liu, Alan Soo-Beng Khoo, Wei-Hua Jia, Yun-Miao Guo, Qi-Shen Feng, Fu-Tuo Feng, Qian Cui, Ming-Yuan Chen, Li-Zhen Chen, Yu-Sun Chang, Chien-Jen Chen, James D. McKay, Wan-Lun Hsu, Pei-Jen Lou, Yoon-Ming Chin, Kai Yu, Ching-Ching Ng, Wen-Hui Su, Jin-Xin Bei
Supplemental Figure 1S. Individual Study Results from GWAS Meta-Analysis and Replication Studies for Selected SNPs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5e683123111b2ee46fe4febca3897d
https://doi.org/10.1158/1055-9965.22437973.v1
https://doi.org/10.1158/1055-9965.22437973.v1
Autor:
Allan Hildesheim, Yi-Xin Zeng, Jian-Jun Liu, Gang-Qiao Zhou, Hongxin Zhang, Yun-Fei Xia, Ka-Po Tse, Soo-Hwang Teo, Kin-Choo Pua, Hao-Yuan Mo, Wen-Sheng Liu, Alan Soo-Beng Khoo, Wei-Hua Jia, Yun-Miao Guo, Qi-Shen Feng, Fu-Tuo Feng, Qian Cui, Ming-Yuan Chen, Li-Zhen Chen, Yu-Sun Chang, Chien-Jen Chen, James D. McKay, Wan-Lun Hsu, Pei-Jen Lou, Yoon-Ming Chin, Kai Yu, Ching-Ching Ng, Wen-Hui Su, Jin-Xin Bei
Background: Genetic loci within the major histocompatibility complex (MHC) have been associated with nasopharyngeal carcinoma (NPC), an Epstein-Barr virus (EBV)-associated cancer, in several GWAS. Results outside this region have varied.Methods: We c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc7b076eeeb3eff007050915cf52da4
https://doi.org/10.1158/1055-9965.c.6516145.v1
https://doi.org/10.1158/1055-9965.c.6516145.v1
Autor:
Hans Prakash Sathasivam, Selina Yuet Ling Chew, Wee‐Ric Kim, Chee‐Lynn Saw, Lu Ping Tan, Tengku Ahmad Damitri Al‐Astani Tengku Din, Nurul‐Ashikin Adam, Harissa Husainy Hasbullah, Wan Fatihah Wan Sohaimi, Tee‐Yong Tan, Chee‐Lun Lum, Kin‐Choo Pua, Alan Soo‐Beng Khoo
Publikováno v:
Clinical Otolaryngology. 47:486-490
Autor:
Munirah Ahmad, Shazlan-Noor Suhaimi, Tai-Lin Chu, Norazlin Abdul Aziz, Noor-Kaslina Mohd Kornain, D S Samiulla, Kwok-Wai Lo, Chew-Hee Ng, Alan Soo-Beng Khoo
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191295 (2018)
Copper(II) ternary complex, [Cu(phen)(C-dmg)(H2O)]NO3 was evaluated against a panel of cell lines, tested for in vivo efficacy in nasopharyngeal carcinoma xenograft models as well as for toxicity in NOD scid gamma mice. The Cu(II) complex displayed b
Externí odkaz:
https://doaj.org/article/fed81a86d7b44b029dccacf44d917bb8
Autor:
Chin King Looi, Li Zhe Wong, Lu Ping Tan, Alan Soo-Beng Khoo, Brian Ming OuYong, Felicia Fei-Lei Chung, Chun-Wai Mai, Ling-Wei Hii, Lesley Jia Wei Pua, Gibson Qi Sheng Yu, Kitson Liew, Shiau Ying Tham, Wei-Meng Lim, Chee-Onn Leong, Munirah Ahmad
Publikováno v:
Cancer Letters. 504:81-90
Despite recent in advances in the management of nasopharyngeal carcinoma (NPC), development of targeted therapy remains challenging particularly in patients with recurrent or metastatic disease. To search for clinically relevant targets for the treat
Publikováno v:
Advances in Virology, Vol 2016 (2016)
Nanometre-sized vesicles, also known as exosomes, are derived from endosomes of diverse cell types and present in multiple biological fluids. Depending on their cellular origins, the membrane-bound exosomes packed a variety of functional proteins and
Externí odkaz:
https://doaj.org/article/5b15b96ae8b1429dac59de6e5462862c