Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Alan Soo Beng Khoo"'
Autor:
Ke-En Tan, Wei Lun Ng, Georgi K. Marinov, Ken Hung-On Yu, Lu Ping Tan, Ee Shan Liau, Sook Yan Goh, Kok Siong Yeo, Kevin Y. Yip, Kwok-Wai Lo, Alan Soo-Beng Khoo, Lee-Fah Yap, Chee-Kwee Ea, Yat-Yuen Lim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Epstein-Barr virus (EBV) has been recently found to generate novel circular RNAs (circRNAs) through backsplicing. However, comprehensive catalogs of EBV circRNAs in other cell lines and their functional characterization are still lacking. In
Externí odkaz:
https://doaj.org/article/6f280b89ec074aafa9b102c63d7b3441
Autor:
Sin-Yeang Teow, Kitson Liew, Mohd Firdaus Che Mat, Marini Marzuki, Norazlin Abdul Aziz, Tai-Lin Chu, Munirah Ahmad, Alan Soo-Beng Khoo
Publikováno v:
BMC Biotechnology, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background In vitro modelling of cancer cells is becoming more complex due to prevailing evidence of intimate interactions between cancer cells and their surrounding stroma. A co-culture system which consists of more than one cell type is ph
Externí odkaz:
https://doaj.org/article/82268afa72214fc0850cfbaaa5dad36b
Autor:
Xiao-Yu Zuo, Qi-Sheng Feng, Jian Sun, Pan-Pan Wei, Yoon-Ming Chin, Yun-Miao Guo, Yun-Fei Xia, Bo Li, Xiao-Jun Xia, Wei-Hua Jia, Jian-Jun Liu, Alan Soo-Beng Khoo, Taisei Mushiroda, Ching-Ching Ng, Wen-Hui Su, Yi-Xin Zeng, Jin-Xin Bei
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-11 (2019)
Abstract Background The male predominance in the incidence of nasopharyngeal carcinoma (NPC) suggests the contribution of the X chromosome to the susceptibility of NPC. However, no X-linked susceptibility loci have been examined by genome-wide associ
Externí odkaz:
https://doaj.org/article/38e8451dc36b44588032740922b7d6f0
Autor:
Lesley Jia Wei Pua, Chun-Wai Mai, Felicia Fei-Lei Chung, Alan Soo-Beng Khoo, Chee-Onn Leong, Wei-Meng Lim, Ling-Wei Hii
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1108 (2022)
c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) family members integrate signals that affect proliferation, differentiation, survival, and migration in a cell context- and cell type-specific way. JNK and p38 MAPK activit
Externí odkaz:
https://doaj.org/article/3560b14fb2ec40e08ea06bb523b2a7aa
Publikováno v:
Human Genomics, Vol 12, Iss 1, Pp 1-21 (2018)
Abstract Background The mechanism underlying chromosome rearrangement in nasopharyngeal carcinoma (NPC) remains elusive. It is known that most of the aetiological factors of NPC trigger oxidative stress. Oxidative stress is a potent apoptotic inducer
Externí odkaz:
https://doaj.org/article/d16c553c48554608a7650d6728b62aa5
Autor:
Allan Hildesheim, Yi-Xin Zeng, Jian-Jun Liu, Gang-Qiao Zhou, Hongxin Zhang, Yun-Fei Xia, Ka-Po Tse, Soo-Hwang Teo, Kin-Choo Pua, Hao-Yuan Mo, Wen-Sheng Liu, Alan Soo-Beng Khoo, Wei-Hua Jia, Yun-Miao Guo, Qi-Shen Feng, Fu-Tuo Feng, Qian Cui, Ming-Yuan Chen, Li-Zhen Chen, Yu-Sun Chang, Chien-Jen Chen, James D. McKay, Wan-Lun Hsu, Pei-Jen Lou, Yoon-Ming Chin, Kai Yu, Ching-Ching Ng, Wen-Hui Su, Jin-Xin Bei
Supplemental Table 1S. Sequenome Primer Design for 43 SNPs included in Our Replications Studies. Supplemental Table 2S. Results from NPC GWAS Meta-Analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f92857be4594d41c9818f0ae9a5c0b
https://doi.org/10.1158/1055-9965.22437970
https://doi.org/10.1158/1055-9965.22437970
Autor:
Allan Hildesheim, Yi-Xin Zeng, Jian-Jun Liu, Gang-Qiao Zhou, Hongxin Zhang, Yun-Fei Xia, Ka-Po Tse, Soo-Hwang Teo, Kin-Choo Pua, Hao-Yuan Mo, Wen-Sheng Liu, Alan Soo-Beng Khoo, Wei-Hua Jia, Yun-Miao Guo, Qi-Shen Feng, Fu-Tuo Feng, Qian Cui, Ming-Yuan Chen, Li-Zhen Chen, Yu-Sun Chang, Chien-Jen Chen, James D. McKay, Wan-Lun Hsu, Pei-Jen Lou, Yoon-Ming Chin, Kai Yu, Ching-Ching Ng, Wen-Hui Su, Jin-Xin Bei
Supplemental Figure 1S. Individual Study Results from GWAS Meta-Analysis and Replication Studies for Selected SNPs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5e683123111b2ee46fe4febca3897d
https://doi.org/10.1158/1055-9965.22437973.v1
https://doi.org/10.1158/1055-9965.22437973.v1
Autor:
Allan Hildesheim, Yi-Xin Zeng, Jian-Jun Liu, Gang-Qiao Zhou, Hongxin Zhang, Yun-Fei Xia, Ka-Po Tse, Soo-Hwang Teo, Kin-Choo Pua, Hao-Yuan Mo, Wen-Sheng Liu, Alan Soo-Beng Khoo, Wei-Hua Jia, Yun-Miao Guo, Qi-Shen Feng, Fu-Tuo Feng, Qian Cui, Ming-Yuan Chen, Li-Zhen Chen, Yu-Sun Chang, Chien-Jen Chen, James D. McKay, Wan-Lun Hsu, Pei-Jen Lou, Yoon-Ming Chin, Kai Yu, Ching-Ching Ng, Wen-Hui Su, Jin-Xin Bei
Background: Genetic loci within the major histocompatibility complex (MHC) have been associated with nasopharyngeal carcinoma (NPC), an Epstein-Barr virus (EBV)-associated cancer, in several GWAS. Results outside this region have varied.Methods: We c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc7b076eeeb3eff007050915cf52da4
https://doi.org/10.1158/1055-9965.c.6516145.v1
https://doi.org/10.1158/1055-9965.c.6516145.v1
Autor:
Hans Prakash Sathasivam, Selina Yuet Ling Chew, Wee‐Ric Kim, Chee‐Lynn Saw, Lu Ping Tan, Tengku Ahmad Damitri Al‐Astani Tengku Din, Nurul‐Ashikin Adam, Harissa Husainy Hasbullah, Wan Fatihah Wan Sohaimi, Tee‐Yong Tan, Chee‐Lun Lum, Kin‐Choo Pua, Alan Soo‐Beng Khoo
Publikováno v:
Clinical Otolaryngology. 47:486-490
Autor:
Munirah Ahmad, Shazlan-Noor Suhaimi, Tai-Lin Chu, Norazlin Abdul Aziz, Noor-Kaslina Mohd Kornain, D S Samiulla, Kwok-Wai Lo, Chew-Hee Ng, Alan Soo-Beng Khoo
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191295 (2018)
Copper(II) ternary complex, [Cu(phen)(C-dmg)(H2O)]NO3 was evaluated against a panel of cell lines, tested for in vivo efficacy in nasopharyngeal carcinoma xenograft models as well as for toxicity in NOD scid gamma mice. The Cu(II) complex displayed b
Externí odkaz:
https://doaj.org/article/fed81a86d7b44b029dccacf44d917bb8