Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alan S. Taylor"'
Autor:
Joseph J. DeGeorge, L. F. Sancilio, M. E. Brower, C. J. Sun, Wendelyn J. Schmidt, S. Williams, W. D. Mcguinn, V. Whitehurst, P. A. Andrews, H. V. Sheevers, Doo Young Lee-Ham, Alan S. Taylor, Chang Ho Ahn, L. Pei, M. Y. Chun, S C Tripathi, T. Du, Y. S. Choi, W. M. Vogel
Publikováno v:
Regulatory Toxicology and Pharmacology. 25:189-193
The standard approaches for the preclinical development of chronically administered drugs also apply to most respiratory drugs. Modifications from the standard preclinical development plan, however, may be necessary if the drug is administered intran
Publikováno v:
The Electricity Journal. 8:56-66
There is no “one size fits all” role for renewables in utility resource plans, so the benefits and potential of renewables depend on careful analysis of the specifics of a given utility's situation. As the state of the modeling art advances, and
Publikováno v:
Drug Information Journal. 30:177-179
When serious adverse effects are observed in preclinical safety studies being conducted after the initial investigational new drug (IND) submission, the sponsor is required to submit an IND safety report, referred to as an S-2 report. This is especia
Autor:
Alan S. Taylor, Joseph J. DeGeorge, James G. Farrelly, Albert F. DeFelice, Chang-Ho Ahn, Joy A. Cavagnaro, Alexander Jordan, Lauren E. Black
Publikováno v:
Antisense Research and Development. 4:299-301
This article describes pharmacology and toxicity studies for oligonucleotide drugs that are recommended for inclusion in the initial Investigational New Drug Application (IND), a first request to use an investigational drug in clinical trials. Recent
Autor:
Wallace P. Adams, Roger L. Williams, Rashmikant M. Patel, Guirag Poochikian, Alan S. Taylor, Gregory P. Burke
Publikováno v:
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine. 7(2)
Regulatory requirements for modifications to an approved innovator metered dose inhaler (pressurized MDI; USP nomenclature: inhalation aerosol) and for development of a new generic product are discussed. Although many of the requirements apply genera
Publikováno v:
Prostaglandins. 29:449-458
5,8,11,14-eicosatetraynoic acid (ETYA), a widely used inhibitor of cyclooxygenase and lipoxygenase, inhibited the incorporation of 14C-arachidonic acid into cell lipids of the murine thymoma EL4 whereas oleic acid had no effect. Inhibition appeared t
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 833:229-238
Evidence is presented that the murine thymoma EL4 and cytotoxic T lymphocyte clones possess two distinct long-chain fatty acyl-CoA synthetase activities. One enzyme shows activity toward a broad spectrum of fatty acid substrates, similar to the long-
Autor:
Alan S. Taylor, Eugene M. Johnson
Publikováno v:
Biochemical Pharmacology. 29:113-115