Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Alan S. Kirschner"'
1
Pyridazinoquinolinetriones as NMDA Glycine-Site Antagonists with Oral Antinociceptive Activity in a Model of Neuropathic Pain
Autor: Edward P. Vacek, Thomas Michael Bare, Martin C. Dyroff, Kathy L. Neilson, Rebecca Urbanek, J. Empfield, Alan S. Kirschner, Christine Barlaam, Joseph Lewis, Chi-Ming C. Lee, Wenhua Xiao, Megan Murphy, Vernon Alford, Janet Marie Forst, Gary Steelman, Shephali Trivedi, Richard A. Keith, Frances M. Mclaren, Dean G. Brown, Keith John Herzog, Horchler Carey
Publikováno v: Journal of Medicinal Chemistry. 50:3113-3131
A series of 7-chloro-2,3-dihydro-2-[1-(pyridinyl)alkyl]-pyridazino[4,5-b]quinoline-1,4,10(5H)-triones were synthesized and found to have potent activity at the glycine site of the NMDA receptor. In some cases, these compounds possessed poor aqueous s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e6df439ce03cdca255c44c5222f7a4
https://doi.org/10.1021/jm060212s
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2
The discovery of orally-active pseudopeptide antagonists of the atrial natriuretic peptide clearance receptor
Autor: Vernon Alford, Alan S. Kirschner, Russell C. Mauger, Megan Murphy, William E. Palmer, Philip D. Edwards, Jean M. Surian, Greg A. Hostetler, Kara K. Pine, Steven Dock, Cathy Dantzman, Mark Sylvester, Edward P. Vacek, William L. Rumsey, Steven E. Cook, Russell Bialecki, Chris Allan Veale, Timothy Wayne Davenport, Gary Steelman, Robert Toms Jacobs, David Aharony
Publikováno v: Peptides for the New Millennium ISBN: 0792364457
Robert T. Jacobs, David Aharony, Vernon Alford, Russell A. Bialecki, Steven E. Cook, Cathy L. Dantzman, Timothy W. Davenport, Steven T. Dock, Philip D. Edwards, Greg A. Hostetler, Alan Kirschner, Russell C. Mauger, Megan Murphy, William E. Palmer, Ka
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d2e4e220083fe198699b2b394106cf0b
https://doi.org/10.1007/0-306-46881-6_102
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4
Synthesis of 123mTe-nucleophiles: Potential use in the synthesis of new 123mTe-radiopharmaceuticals
Autor: Garo P. Basmadjian, George R. Parker, Stanley L. Mills, Robert A. Magarian, Rodney D. Ice, Alan S. Kirschner
Publikováno v: The International Journal of Applied Radiation and Isotopes. 31:517-520
Elemental powdered tellurium and sodium borohydride react in water or ethanol to give sodium telluride, sodium hydrogen telluride, or sodium ditelluride depending on the ratio of the reactants used and pH of the medium. These inorganic telluride and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f47416fe31cdba250134fd9db393318
https://doi.org/10.1016/0020-708x(80)90317-8
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6
Kit preparation of radioiodinated o-iodohippuran
Autor: Garo P. Basmadjian, George H. Hinklex, Rodney D. Ice, Alan S. Kirschner
Publikováno v: Journal of pharmaceutical sciences. 70(3)
The purpose of this study was to evaluate a kit preparation for radioiodinated o -iodohippuran (I). All ingredients, excluding the radionuclide, were packaged in a ready-to-use kit for easy, quick formulation. Electrophoresis was utilized to evaluate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251685c4beae37bad4b143182439bb09
https://pubmed.ncbi.nlm.nih.gov/7264899
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7
125I-UdR Induced Division Delay
Autor: Dennis B. Leeper, Martin H. Schneiderman, Alan S. Kirschner, Kurt G. Hofer, Bruce F. Kimler
Mitotic selection for cell cycle analysis was used to investigate the effects of 3 H and 125 I, incorporated into DNA, on the cell cycle progression of Chinese hamster ovary (CHO) cells. The results indicate that S-phase cells were delayed and G 2 ce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be16279f16bdf79739b9f3ddbfe3cef6
https://europepmc.org/articles/PMC1473458/
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