Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Alan Rawls"'
Autor:
Mostafa Hamada, Kyle Steven Varkoly, Omer Riyadh, Roxana Beladi, Ganesh Munuswamy-Ramanujam, Alan Rawls, Jeanne Wilson-Rawls, Hao Chen, Grant McFadden, Alexandra R. Lucas
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1167 (2024)
The urokinase-type plasminogen activator receptor (uPAR) is a unique protease binding receptor, now recognized as a key regulator of inflammation. Initially, uPA/uPAR was considered thrombolytic (clot-dissolving); however, recent studies have demonst
Externí odkaz:
https://doaj.org/article/4d7e62f3f3fc45fc8b1b9bc45bfb17e0
Autor:
Cherie Alissa Lynch, Sofia A. Acosta, Douglas M. Anderson, Gavin E. Rogers, Jeanne Wilson-Rawls, Alan Rawls
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 5019 (2024)
Efficient repair of skeletal muscle relies upon the precise coordination of cells between the satellite cell niche and innate immune cells that are recruited to the site of injury. The expression of pro-inflammatory cytokines and chemokines such as T
Externí odkaz:
https://doaj.org/article/585ea014b44544daabf95d208c305482
Autor:
Alan Rawls, Bridget K. Diviak, Cameron I. Smith, Grant W. Severson, Sofia A. Acosta, Jeanne Wilson-Rawls
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1536 (2023)
Muscular dystrophies are a heterogeneous group of genetic muscle-wasting disorders that are subdivided based on the region of the body impacted by muscle weakness as well as the functional activity of the underlying genetic mutations. A common featur
Externí odkaz:
https://doaj.org/article/20a7fa29db7d4cf2a5623808cbb976db
Autor:
Alexander B. Andre, Katherina P. Rees, Samantha O’Connor, Grant W. Severson, Jason M. Newbern, Jeanne Wilson-Rawls, Christopher L. Plaisier, Alan Rawls
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: The expression of proinflammatory signals at the site of muscle injury are essential for efficient tissue repair and their dysregulation can lead to inflammatory myopathies. Macrophages, neutrophils, and fibroadipogenic progenitor cells r
Externí odkaz:
https://doaj.org/article/67782f314e6b445991619e95e0404d50
Autor:
Alexander B. Andre, Liqiang Zhang, Jalen D. Nix, Nora Elmadbouly, Alexandra R. Lucas, Jeanne Wilson-Rawls, Alan Rawls
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1154 (2022)
Duchenne muscular dystrophy is an X-linked disease afflicting 1 in 3500 males that is characterized by muscle weakness and wasting during early childhood, and loss of ambulation and death by early adulthood. Chronic inflammation due to myofiber insta
Externí odkaz:
https://doaj.org/article/e7f03815846f47c1bbbb1c5e758bc827
Autor:
Cameron I. Smith, Joanna Palade, Jeanne Wilson-Rawls, Jacquelyn Kilbourne, Brent Vernon, Mehdi Nikkhah, Amrita Pal, Byron A. Alarcon-Benedetto, Alan Rawls, Supriya Nagaraju
Publikováno v:
Acta Biomaterialia. 107:138-151
Injectable hydrogels provide a powerful and non-invasive approach for numerous applications in cell transplantation, growth factor delivery, tissue regeneration and so forth. The properties of injectable hydrogels should be well-tuned for specific ap
Autor:
Shannon O'Brien, Heather C. Hrach, Hannah S Steber, Alan Rawls, Marco Mangone, Jason M. Newbern
Publikováno v:
Human Molecular Genetics
Duchenne muscular dystrophy (DMD) is a lethal, X-linked disease characterized by progressive muscle degeneration. The condition is driven by nonsense and missense mutations in the dystrophin gene, leading to instability of the sarcolemma and skeletal
Publikováno v:
Acta Biomaterialia. 97:296-309
Development of an ex vivo culture system to expand satellite cells, the resident muscle stem cell population, will be necessary for the development of their use as therapeutics. The loss of the niche environment is often cited as the reason that cult
Autor:
Elizabeth D Hutchins, Glenn J Markov, Walter L Eckalbar, Rajani M George, Jesse M King, Minami A Tokuyama, Lauren A Geiger, Nataliya Emmert, Michael J Ammar, April N Allen, Ashley L Siniard, Jason J Corneveaux, Rebecca E Fisher, Juli Wade, Dale F DeNardo, J Alan Rawls, Matthew J Huentelman, Jeanne Wilson-Rawls, Kenro Kusumi
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105004 (2014)
Lizards, which are amniote vertebrates like humans, are able to lose and regenerate a functional tail. Understanding the molecular basis of this process would advance regenerative approaches in amniotes, including humans. We have carried out the firs
Externí odkaz:
https://doaj.org/article/268a2c826f8648f1a3e049ebcb83ce71
Autor:
Joanna Palade, Andrew R. Clark, Ruth M. Elsey, Alan Rawls, Cindy Xu, Kenro Kusumi, Russell Bourgeois, Cameron I. Smith, Jeanne Wilson-Rawls, Rebecca E. Fisher, Samuel Sampson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports
Reptiles are the only amniotes that maintain the capacity to regenerate appendages. This study presents the first anatomical and histological evidence of tail repair with regrowth in an archosaur, the American alligator. The regrown alligator tails c