Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alan R. Godwin"'
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1829:571-579
PARN, Nocturnin and Angel are three of the multiple deadenylases that have been described in eukaryotic cells. While each of these enzymes appear to target poly(A) tails for shortening and influence RNA gene expression levels and quality control, the
Publikováno v:
Development Genes and Evolution. 217:413-420
Hox genes are re-expressed during regeneration in many species. Given their important role in body plan development, it has been assumed, but not directly shown, that they play a functional role in regeneration. In this paper we show that morpholino-
A uterine decidual cell cytokine ensures pregnancy-dependent adaptations to a physiological stressor
Autor:
Michael J. Soares, Gouli Dai, Alan R. Godwin, Judy H. Dunmore, Toshihiro Konno, S.M. Khorshed Alam, Danhua Wang, Lu Lu
Publikováno v:
Development. 134:407-415
In the mouse, decidual cells differentiate from uterine stromal cells in response to steroid hormones and signals arising from the embryo. Decidual cells are crucially involved in creating the intrauterine environment conducive to embryonic developme
Autor:
Christopher S. Potter, John P. Sundberg, Alan R. Godwin, Alexander Awgulewitsch, Nathanael D. Pruett, Mary Ann Baybo, Michael J. Kern
Publikováno v:
Experimental and molecular pathology. 99(3)
The cholesterol-metabolizing enzyme sterol O-acetyltransferase (SOAT1) is implicated in an increasing number of biological and pathological processes in a number of organ systems, including the differentiation of the hair shaft. While the functional
Autor:
David R. Hyde, Michael P. Sarras, Ryan Thummel, Alan R. Godwin, Martin Perry, Shan Bai, Jeffrey L. Brewer, Peizhen Song, Jeffrey McDermott, Xiaoming Zhang
Publikováno v:
Developmental Dynamics. 235:336-346
Increased interest in using zebrafish as a model organism has led to a resurgence of fin regeneration studies. This has allowed for the identification of a large number of gene families, including signaling molecules and transcription factors, which
Autor:
Alan R. Godwin, Patricia Cazcarro, Dale R. Abrahamson, Judy H. Dunmore, Brooke M. Steenhard, Patricia L. St. John, Kathryn Isom
Publikováno v:
Journal of the American Society of Nephrology. 16:1623-1631
Many stages of nephrogenesis can be studied using cultured embryonic kidneys, but there is no efficient technique available to readily knockdown or overexpress transgenes for rapid evaluation of resulting phenotypes. Embryonic stem (ES) cells have un
Autor:
Ryan Thummel, Richard Evans, Alan R. Godwin, Shan Bai, Li Li, Motoharu Seiki, Hideaki Nagase, Jeffrey McDermott, Michael P. Sarras, Yoshifumi Itoh
Publikováno v:
Matrix Biology. 24:247-260
Matrix metalloproteinases (MMPs) play key roles in the turnover of extracellular matrix (ECM) and, thereby, function as key regulators of cell-ECM interactions during development. In spite of their importance during developmental processes, relativel
Autor:
Alan R. Godwin, Brian Sauer, Jeffrey McDermott, Ryan Thummel, Christopher T. Burket, David R. Hyde, Jeffrey L. Brewer, Michael P. Sarras, Martin Perry, Li Li
Publikováno v:
Developmental Dynamics. 233:1366-1377
Cre-mediated site-specific recombination has become an invaluable tool for manipulation of the murine genome. The ability to conditionally activate gene expression or to generate chromosomal alterations with this same tool would greatly enhance zebra
Publikováno v:
Proceedings of the National Academy of Sciences. 101:16543-16548
Successful species develop strategies to optimize their reproductive performance. This optimization likely includes the evolution of genes that specifically permit reproduction in physiologically challenging conditions. The prolactin (PRL) family gen
Publikováno v:
Developmental Biology. 274:318-333
Vertebrate Hox genes are generally believed to initiate expression at the primitive streak or early neural plate stages. The timing and spatial restrictions of the Hox expression patterns during these stages correlate well with their demonstrated rol