Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Alan R. Day"'
Publikováno v:
International Journal of Peptide and Protein Research. 22:305-312
The synthesis and resolution of the amino acid β-cyclopropylalanine (Cpr) and its incorporation into four enkephalin analogs is reported. The analogs prepared were: Tyr - l - Cpr - Gly - Phe - Pen (des - COOH - Nle = n - pentylamide = Pen) (l-Cpr2-P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e37005a4bce9191f8377d876526c7d4e
https://doi.org/10.1111/j.1399-3011.1983.tb02096.x
https://doi.org/10.1111/j.1399-3011.1983.tb02096.x
Autor:
H.J. Showell, Richard J. Freer, Alan R. Day, Elmer L. Becker, Natesa Muthukumaraswamy, Arthur Wu, Delia I. Pinon
Publikováno v:
Biochemistry. 21:257-263
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5a7e7b43159500edb22826b6c991a5
https://doi.org/10.1021/bi00531a009
https://doi.org/10.1021/bi00531a009
Publikováno v:
Biochemical and Biophysical Research Communications. 90:1364-1370
Summary [ 14 C]arachidonic acid incorporation into phosphatidylinositol from rabbit neutrophils pretreated with cytochalasin B was increased within 2 min by the synthetic peptide formyl-methionyl-leucyl-phenylalanine and the Ca 2+ ionophore A23187. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1654686744c3b5fed474f369c8f152e
https://doi.org/10.1016/0006-291x(79)91186-0
https://doi.org/10.1016/0006-291x(79)91186-0
Publikováno v:
Biochemical and Biophysical Research Communications. 74:592-598
The proton NMR spectra in aqueous and dimethylsulfoxide solutions have been obtained at 360 MHz for: methionine-enkephalin, leucine-enkephalin, (Phe 1 )-methionine-enkephalin, norleucine-enkephalin, and des-amino-methionine-enkephalin. Resonance assi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b698336b4552eb949a058317ac6ca69f
https://doi.org/10.1016/0006-291x(77)90344-8
https://doi.org/10.1016/0006-291x(77)90344-8
Autor:
Candace B. Pert, Richard J. Freer, Srinivasabhatt Aswanikumar, Barbara A. Corcoran, Elliot Schiffmann, Elmer L. Becker, H.J. Showell, Alan R. Day
Publikováno v:
Biochemical and Biophysical Research Communications. 74:810-817
[3H]formylNorleu-Leu-Phe, a potent leucocyte chemoattractant, binds specifically to a site on rabbit neutrophils with an affinity of 1.5 × 10−9 M. Other acylated peptide chemoattractants displace this binding at concentrations closely related to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e9905c9baf8261f8008948dbe12f19
https://doi.org/10.1016/0006-291x(77)90375-8
https://doi.org/10.1016/0006-291x(77)90375-8
Autor:
Richard J. Freer, Alan R. Day
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 14:381-391
In a previous study methionine-enkephalin (H-Tyr-Gly-Gly-Phe-Met-OH) and four analogs and homologs were synthesized and compared to morphine with respect to their ability to inhibit electrically evoked contractions of the isolated guinea pig ileum. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c987f7ec6b290b18cce43a96fe93fade
https://doi.org/10.1002/jlcr.2580140311
https://doi.org/10.1002/jlcr.2580140311
Publikováno v:
European Journal of Pharmacology. 65:349-354
An angiotensin antagonist, Sarcosyl 1 -Cysteinyl(S-Methyl) 8 -angiotensin I [Sar 1 -Cys(Me) 8 -ANG I] was synthesized and its pharmacological properties evaluated in vivo (rat blood pressure assay) and in vitro (rabbit aortic strip, guinea-pig ileum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b5238ef5a92a4439e0df8476004868
https://doi.org/10.1016/0014-2999(80)90338-6
https://doi.org/10.1016/0014-2999(80)90338-6
Autor:
Barbara A. Corcoran, Candace B. Pert, Krishnamoorthy Venkatasubramanian, S. Aswanikumar, Richard J. Freer, Jeremy S. Brown, Erhard Gross, A.H. Showell, Alan R. Day, Elliott Schiffmann, Elmer L. Becker
Publikováno v:
FEBS Letters. 117:1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b87b3742070cdbb87a4acf19d0eb494
https://doi.org/10.1016/0014-5793(80)80900-8
https://doi.org/10.1016/0014-5793(80)80900-8
Publikováno v:
FEBS letters. 119(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800f1a72cea4030ab4d6e02c64223980
https://pubmed.ncbi.nlm.nih.gov/6775976
https://pubmed.ncbi.nlm.nih.gov/6775976
Publikováno v:
Peptides. 1(4)
The following peptides have been synthesized using classical mixed anhydride methods: Boc-Leu-Phe-OH, Boc-Phe-Leu-Phe-OH, Boc-Leu-Phe-Leu-Phe-OH and Boc-Phe-Leu-Phe-Leu-Phe-OH. The tri, tetra and pentapeptides inhibit Formyl-Met-Leu-Phe-OH induced re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb1f2c1e83c703731951272ec33b2e0
https://pubmed.ncbi.nlm.nih.gov/7301634
https://pubmed.ncbi.nlm.nih.gov/7301634