Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alan R. Culwell"'
Autor:
Susan D. Craddock, Russell E. Rydel, Virginia L. Smith-Swintosky, L. Creed Pettigrew, Mark P. Mattson, Alan R. Culwell
Publikováno v:
Journal of Neurochemistry. 63:781-784
The beta-amyloid precursor protein (beta APP) is the source of the amyloid beta-peptide that accumulates in the brain in Alzheimer's disease. A major processing pathway for beta APP involves an enzymatic cleavage within the amyloid beta-peptide seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1a8205dc25a4f2ce06b03679ac2dcc
https://doi.org/10.1046/j.1471-4159.1994.63020781.x
https://doi.org/10.1046/j.1471-4159.1994.63020781.x
Publikováno v:
Brain Research. 718:13-24
We have reported that the local administration of serine protease inhibitors (amyloid precursor protein with the Kunitz insert (APP K + ), aprotinin, and Lupeptin) to the rat sciatic nerve determines a sprouting response of myelinated axons, prolifer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1a657dfd9c8a7b046129e3fa5e3fe9
https://doi.org/10.1016/0006-8993(95)01555-8
https://doi.org/10.1016/0006-8993(95)01555-8
Autor:
Frederick Esch, Mark P. Mattson, Alan R. Culwell, Bin Cheng, Russell E. Rydel, Ivan Lieberburg
Publikováno v:
Neuron. 10(2)
The β-amyloid precursor protein (βAPP) is a membrane-spanning glycoprotein that is the source of the β-amyloid peptide (βAP) which accumulates as senile plaques in the brains of patients with Alzheimer's disease. βAPP is normally processed such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d990541d509b46d3d086c0b6f20f62b4
https://pubmed.ncbi.nlm.nih.gov/8094963
https://pubmed.ncbi.nlm.nih.gov/8094963
Autor:
Doris A. Sparrow, Merry Kovar, James T. Sparrow, Germain J. P. Fernando, Alan R. Culwell, Antonio M. Gotto
Publikováno v:
Biochemistry. 31(4)
We have previously shown that the synthetic peptide apoE(129-169) forms lipid-peptide complexes with dimyristoylphosphatidylcholine (DMPC) with an L:P molar ratio of 125:1; the peptide in the isolated complex contains approximately 56% alpha-helicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4f3ad2f9e2a8d3da962d11baf68986
https://pubmed.ncbi.nlm.nih.gov/1734956
https://pubmed.ncbi.nlm.nih.gov/1734956
Autor:
Russell W. Blacher, Donald McClure, Eric C. Beattie, Tilman Oltersdorf, Frederick Esch, Pamela S. Keim, Alan R. Culwell, Pamela J. Ward
Publikováno v:
Science (New York, N.Y.). 248(4959)
The amyloid beta peptide (A beta P) is a small fragment of the much larger, broadly distributed amyloid precursor protein (APP). Abundant A beta P deposition in the brains of patients with Alzheimer's disease suggests that altered APP processing may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d919fa82f1eaa7e414e53db86a5011
https://pubmed.ncbi.nlm.nih.gov/2111583
https://pubmed.ncbi.nlm.nih.gov/2111583
Autor:
Antonio M. Gotto, Lee D. Blumenthal, Henry J. Pownall, James T. Sparrow, Alan R. Culwell, Fu Juan Hsu
Publikováno v:
Biochemistry. 16:5427-5431
We have used thrombin to cleave apolipoprotein C-III-1 into two fragments constituting residues 1-40 (apoLP-C-III-A) and 41-79 (apoLP-C-III-B). The lipid binding properties of these fragments with dimyristoyl- and 1-palmitoyl-2-oleoylphosphatidylchol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09ecc7db1b9616834448b9ad5f9ea9d
https://doi.org/10.1021/bi00644a004
https://doi.org/10.1021/bi00644a004
Publikováno v:
Peptides ISBN: 9789401095976
Peptides
Peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb38e3da1b1a3e334729fbae9e6b3bcf
https://doi.org/10.1007/978-94-010-9595-2_60
https://doi.org/10.1007/978-94-010-9595-2_60
Inhibition of a common human anti-hepatitis B surface antigen idiotype by a cyclic synthetic peptide
Autor:
Ronald C. Kennedy, Alan R. Culwell, F. B. Hollinger, Yanuario Sanchez, Joseph L. Melnick, James T. Sparrow, Gordon R. Dreesman, Irina Ionescu-Matiu
Publikováno v:
Journal of virology. 46(2)
A common human anti-hepatitis B surface antigen idiotype-anti-idiotype reaction was partially inhibited by a cyclic synthetic hepatitis B surface antigen peptide. Reduction of the intrachain disulfide bond and subsequent alkylation destroyed its inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b6ca4176554407694daf7e9238f9eb1
https://pubmed.ncbi.nlm.nih.gov/6188865
https://pubmed.ncbi.nlm.nih.gov/6188865
Autor:
Pradip K. Bhatnagar, Jonathan E. Foster, Michael Sherlund, Paul Voelker, Anasuya Patel, Martin S. Edelstein, Suresh Kalbag, Kenneth D. Tubman, Daljit Narindray, John L. Hughes, Alan R. Culwell
Publikováno v:
Peptides ISBN: 9789401095976
Peptides
Peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef83e45c239e446b93934ae2e5ff178f
https://doi.org/10.1007/978-94-010-9595-2_59
https://doi.org/10.1007/978-94-010-9595-2_59