Human FSH Glycoform α-Subunit Asparagine52 Glycans: Major Glycan Structural Consistency, Minor Glycan Variation in Abundance

Autor: Viktor Y. Butnev, Jeffrey V. May, Alan R. Brown, Tarak Sharma, Vladimir Y. Butnev, William K. White, David J. Harvey, George R. Bousfield

Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)

Follicle-stimulating hormone (FSH), an α/β heterodimeric glycoprotein hormone, consists of functionally significant variants resulting from the presence or absence of either one of two FSHβ subunit N-glycans. The two most abundant variants are ful

Externí odkaz: https://doaj.org/article/65e5a5b4f54b4fa0b40688d3cc45d7e8

Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei

Autor: Christopher J. McLean, Jon Marles-Wright, Rafael Custodio, Jonathan Lowther, Amanda J. Kennedy, Jacob Pollock, David J. Clarke, Alan R. Brown, Dominic J. Campopiano

Publikováno v: Journal of Lipid Research, Vol 58, Iss 1, Pp 137-150 (2017)

Sphingolipids (SLs) are ubiquitous elements in eukaryotic membranes and are also found in some bacterial and viral species. As well as playing an integral structural role, SLs also act as potent signaling molecules involved in numerous cellular pathw

Externí odkaz: https://doaj.org/article/b88abd542b6b4e52bfb50f3531326388

Culture-independent multilocus sequence typing of Pseudomonas aeruginosa for cross-infection screening

Autor: Chris J. Scotton, Nicholas J. Withers, Philip Mitchelmore, Alan R. Brown, Christopher D. Sheldon

Publikováno v: Diagnostic Microbiology and Infectious Disease. 100:115315

The genotyping of pathogens within cystic fibrosis cohorts is an important process, enabling the detection of transmissible and clinically-important strains. Traditionally this has been via culture-dependent processes. However, culture-independent in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158d8a7f9b126f105056091916349127
https://doi.org/10.1016/j.diagmicrobio.2021.115315

Growth on mannitol-rich media elicits a genome-wide transcriptional response in Burkholderia multivorans that impacts on multiple virulence traits in an exopolysaccharide-independent manner

Autor: Alan R. Brown, Andrea Sass, Carmen C. Denman, Matthew T. Robinson, Eshwar Mahenthiralingam

Publikováno v: Microbiology. 160:187-197

In common with other members of the Burkholderia cepacia complex (BCC), Burkholderia multivorans is capable of producing exopolysaccharide (EPS) when grown on certain mannitol-rich media. The significance of the resulting mucoid phenotype and the gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1eacb0920d488309db4672099f68e40
https://doi.org/10.1099/mic.0.072975-0

Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei

Autor: Christopher J. McLean, Jon Marles-Wright, Rafael Custodio, Jonathan Lowther, Amanda J. Kennedy, Jacob Pollock, David J. Clarke, Alan R. Brown, Dominic J. Campopiano

Publikováno v: Mclean, C J, Marles-wright, J, Custodio, R, Lowther, J, Kennedy, A J, Pollock, J, Clarke, D, Brown, A R & Campopiano, D J 2016, ' Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei ', Journal of lipid research, vol. 58, no. 1, pp. 137-150 . https://doi.org/10.1194/jlr.M071258
Journal of Lipid Research, Vol 58, Iss 1, Pp 137-150 (2017)

Sphingolipids (SLs) are ubiquitous elements in eukaryotic membranes and are also found in some bacterial and viral species. As well as playing an integral structural role, SLs also act as potent signalling molecules involved in numerous cellular path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::79f853f54448271ecf8bf7e47b28af3a
https://www.pure.ed.ac.uk/ws/files/30257988/20161026_Campopiano_McLean_et_al_Text_and_Figs_Resubmission.pdf