Zobrazeno 1 - 10
of 273
pro vyhledávání: '"Alan R Smyth"'
Autor:
Christabella Ng, Helen Barr, Caroline Hoad, Neele S Dellschaft, Robin Spiller, Luca Marciani, Alan R Smyth, Trevor Hill, Colin Crooks, Jochen G Mainz, Alex Menys, Giles Major, Penny A. Gowland
Publikováno v:
NIHR Open Research, Vol 3 (2024)
Background People with cystic fibrosis (CF) can experience recurrent chest infections, pancreatic exocrine insufficiency and gastrointestinal symptoms. New cystic fibrosis transmembrane conductance regulator (CFTR) modulator drugs improve lung functi
Externí odkaz:
https://doaj.org/article/5c1c3656d9e84dffb5b38374c1d6241e
Autor:
Vinishaa Premakumar, Vigilius Gleetus, Zoe Elliott, Bu Hayee, Nicola J Rowbotham, Bethinn Evans, Helen Barr, Siobhán B Carr, Daniel Peckham, Alexander Horsley, Alan R Smyth, Natalie Goodchild, Rebecca J Calthorpe
Publikováno v:
NIHR Open Research, Vol 3 (2024)
Background Gastrointestinal symptoms in cystic fibrosis (CF) are common and intrusive to daily life. Relieving gastrointestinal symptoms was identified as an important research priority and previously explored in an international survey in 2018. Howe
Externí odkaz:
https://doaj.org/article/bf67e4efe61d45ee8b61970134c74365
Autor:
Vinuja Premakumar, Vigilius Gleetus, Zoe Elliott, Bu Hayee, Nicola J Rowbotham, Bethinn Evans, Helen Barr, Siobhán B Carr, Daniel Peckham, Alexander Horsley, Alan R Smyth, Natalie Goodchild, Rebecca J Calthorpe
Publikováno v:
NIHR Open Research, Vol 3 (2023)
Background: Gastrointestinal symptoms in cystic fibrosis (CF) are common and intrusive to daily life. Relieving gastrointestinal symptoms was identified as an important research priority and previously explored in an international survey in 2018. How
Externí odkaz:
https://doaj.org/article/30e967ec12354b958c816835c3f0b6f4
Autor:
Simon C Langton Hewer, Alan R Smyth, Michaela Brown, Ashley P Jones, Helen Hickey, Dervla Kenna, Deborah Ashby, Alexander Thompson, Laura Sutton, Dannii Clayton, Barbara Arch, Łukasz Tanajewski, Vladislav Berdunov, Paula R Williamson
Publikováno v:
Health Technology Assessment, Vol 25, Iss 65 (2021)
Background: People with cystic fibrosis are susceptible to pulmonary infection with Pseudomonas aeruginosa. This may become chronic and lead to increased mortality and morbidity. If treatment is commenced promptly, infection may be eradicated through
Externí odkaz:
https://doaj.org/article/66305f8bb7ed44dbbb98cdbe07146f86
Autor:
Rebecca J. Calthorpe, Caroline Poulter, Alan R. Smyth, Don Sharkey, Jayesh Bhatt, Gisli Jenkins, Amanda L. Tatler
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L285-L296
As survival of extremely preterm infants continues to improve, there is also an associated increase in bronchopulmonary dysplasia (BPD), one of the most significant complications of preterm birth. BPD development is multifactorial resulting from expo
Autor:
Charlie McLeod, Jamie Wood, Siobhain Mulrennan, Sue Morey, André Schultz, Mitch Messer, Kate Spaapen, Yue Wu, Steven Mascaro, Alan R Smyth, Christopher C. Blyth, Steve Webb, Thomas L Snelling, Richard Norman
Publikováno v:
Journal of Cystic Fibrosis. 21:581-587
Treatment for pulmonary exacerbations of cystic fibrosis (CF) can produce a range of positive and negative outcomes. Understanding which of these outcomes are achievable and desirable to people affected by disease is critical to agreeing to goals of
Autor:
Nur Masirah M. Zain, Alan J. Knox, Edward F. Nash, Paul Williams, Karmel Webb, Alan R. Smyth, Miguel Cámara, Helen L. Barr, Douglas L Forrester, Nigel Halliday, Andrew W. Fogarty, Joanna L. Whitehouse, Kenneth D. Bruce
Publikováno v:
Journal of Cystic Fibrosis. 21:626-629
Pseudomonas aeruginosa produces specific signalling molecules, 2-alkyl-4-quinolones (AQs) that are detectable in the sputum of adults with cystic fibrosis (CF) and who have pulmonary infection with this opportunistic pathogen. This study aimed to det
Autor:
Ryan Marsh, Helen Gavillet, Liam Hanson, Christabella Ng, Mandisa Mitchell-Whyte, Giles Major, Alan R Smyth, Damian Rivett, Christopher van der Gast
Publikováno v:
Journal of Cystic Fibrosis. 21:506-513
Most people with cystic fibrosis (pwCF) suffer from gastrointestinal symptoms and are at risk of gut complications. Gut microbiota dysbiosis is apparent within the CF population across all age groups, with evidence linking dysbiosis to intestinal inf
Publikováno v:
Cochrane Database of Systematic Reviews. 2022
Autor:
Giles Major, Christabella Ng, Alan R. Smyth, Anke Jaudszus, Andrew Prayle, Neele Dellschaft, Jochen G. Mainz, Luca Marciani, Robin C. Spiller, Caroline L. Hoad, Lu Ban, Penny A. Gowland, Helen L. Barr
Publikováno v:
Journal of Cystic Fibrosis. 20:591-597
Background and AimsCystic fibrosis (CF) is a multi-system genetic disorder affecting >72,000 people worldwide. Most people with CF experience gastrointestinal symptoms and some will develop complications such as distal intestinal obstruction syndrome