Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Alan R Kay"'
Autor:
Sheng-Yi Wu, Yurong Wen, Nelson B C Serre, Cathrine Charlotte Heiede Laursen, Andrea Grostøl Dietz, Brian R Taylor, Mikhail Drobizhev, Rosana S Molina, Abhi Aggarwal, Vladimir Rancic, Michael Becker, Klaus Ballanyi, Kaspar Podgorski, Hajime Hirase, Maiken Nedergaard, Matyáš Fendrych, M Joanne Lemieux, Daniel F Eberl, Alan R Kay, Robert E Campbell, Yi Shen
Publikováno v:
PLoS Biology, Vol 20, Iss 9, p e3001772 (2022)
Potassium ion (K+) plays a critical role as an essential electrolyte in all biological systems. Genetically-encoded fluorescent K+ biosensors are promising tools to further improve our understanding of K+-dependent processes under normal and patholog
Externí odkaz:
https://doaj.org/article/3acdec6eadb747dba6da2bd4ef33714b
Autor:
Kira M Düsterwald, Christopher B Currin, Richard J Burman, Colin J Akerman, Alan R Kay, Joseph V Raimondo
Publikováno v:
eLife, Vol 7 (2018)
Fast synaptic inhibition in the nervous system depends on the transmembrane flux of Cl- ions based on the neuronal Cl- driving force. Established theories regarding the determinants of Cl- driving force have recently been questioned. Here, we present
Externí odkaz:
https://doaj.org/article/e9a813f7c04348fd9fe281c9429697d1
Autor:
Alan R Kay, Davide Raccuglia, Jon Scholte, Elena Sivan-Loukianova, Christopher A Barwacz, Steven R Armstrong, C Allan Guymon, Michael N Nitabach, Daniel F Eberl
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Most sense organs of arthropods are ensconced in small exoskeletal compartments that hinder direct access to plasma membranes. We have developed a method for exposing live sensory and supporting cells in such structures. The technique uses a viscous
Externí odkaz:
https://doaj.org/article/beb46649bd4c4fb7b06623da59e1f20c
Autor:
Gerald S. Manning, Alan R. Kay
Osmosis is an important force in all living organisms, yet the molecular basis of osmosis is widely misunderstood as arising from differences in water concentration in solutions of differing osmolarities. In 1923 Debye proposed a physical model for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fd9324d5ccb1f8c4026f7b909373f6a
https://doi.org/10.1101/2023.01.02.522450
https://doi.org/10.1101/2023.01.02.522450
Publikováno v:
J Exp Biol
Hemolymph is driven through the antennae of Drosophila melanogaster by the rhythmic contraction of muscle 16 (m16), which runs through the brain. Contraction of m16 results in the expansion of an elastic ampulla, opening ostia and filling the ampulla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c74039bbc5236a149fcf14423ba8fa4
https://europepmc.org/articles/PMC8545754/
https://europepmc.org/articles/PMC8545754/
Autor:
Robert E. Campbell, Klaus Ballanyi, C. C. H. Laursen, Kaspar Podgorski, Vladimir Rancic, B. R. Taylor, Alan R. Kay, Martin Becker, Hajime Hirase, Matyáš Fendrych, Yi Shen, Nelson B.C. Serre, Yurong Wen, M. J. Lemieux, Sheng-Yi Wu, M. Nedergaard, Daniel F. Eberl, A. G. Dietz, Aneel K. Aggarwal
Potassium ions (K+) play a critical role as an essential electrolyte in all biological systems. Here we report the crystal structure-guided optimization and directed evolution of an improved genetically encoded fluorescent K+ biosensor, GINKO2. GINKO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03705f69b2a803ba3c945675278e6b37
https://doi.org/10.1101/2021.10.07.463410
https://doi.org/10.1101/2021.10.07.463410
Autor:
Richard A. Gosselin, Alan R Kay, Ian Norton, Harald Veen, Elhanan Bar-On, Guy Jensen, Jane Thorley Wiedler, Stefanie C Hautz, Johan von Schreeb
Publikováno v:
Prehospital and Disaster Medicine. 34:330-334
It has become clear that disaster relief needs to transition from good intentions or a charity-based approach to a professional, outcome-oriented response. The practice of medicine in disaster and conflict is a profession practiced in environments wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71b81979b7b126eaa30db24f28cbac8
https://doi.org/10.1017/s1049023x19004242
https://doi.org/10.1017/s1049023x19004242
Autor:
Mordecai P. Blaustein, Alan R. Kay
Publikováno v:
The Journal of General Physiology
All animal cells are surrounded by a flexible plasma membrane that is permeable to water and to small ions. Cells thus face a fundamental problem: the considerable tension that their membranes would experience if the osmotic influx of water, driven b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd40a358cbafc3c109d92406a2102b88
https://doi.org/10.1085/jgp.201812274
https://doi.org/10.1085/jgp.201812274
Autor:
Mordecai P. Blaustein, Alan R. Kay
Publikováno v:
The Journal of General Physiology
Kay and Blaustein recount the history of the pump-leak mechanism, which stabilizes cell volume by pumping sodium ions out of cells.
All animal cells are surrounded by a flexible plasma membrane that is permeable to water and to small ions. Cells
All animal cells are surrounded by a flexible plasma membrane that is permeable to water and to small ions. Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddcba5899e1799ba6bb7752fc5a5cb5e
https://pubmed.ncbi.nlm.nih.gov/30782603
https://pubmed.ncbi.nlm.nih.gov/30782603