Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Alan R Hipkiss"'
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45006 (2012)
The dipeptide L-carnosine (β-alanyl-L-histidine) has been described as enigmatic: it inhibits growth of cancer cells but delays senescence in cultured human fibroblasts and extends the lifespan of male fruit flies. In an attempt to understand these
Externí odkaz:
https://doaj.org/article/7915666cf77d43acb2ec0fad85aca619
Autor:
Alan R Hipkiss
Publikováno v:
Frontiers in Aging Neuroscience, Vol 2 (2010)
It is suggested that NAD+ availability strongly affects cellular aging and organism lifespan: low NAD+ availability increases intracellular levels of glycolytic triose phosphates (glyceraldehyde-3-phosphate and dihydroxyacetone-phosphate) which, if n
Externí odkaz:
https://doaj.org/article/3542ec52944c46cf9570b03698a9757c
Autor:
Alan R. Hipkiss
Publikováno v:
Aging and Disease
It is suggested that the non-toxic dipeptide carnosine (beta-alanyl-L-histidine) should be examined as a potential protective agent against COVID-19 infection and inflammatory consequences especially in the elderly. Carnosine is an effective anti-inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a844090277a8f4b74e7b4715f49cb0a6
http://europepmc.org/articles/PMC7390525
http://europepmc.org/articles/PMC7390525
Autor:
Alan R Hipkiss
Publikováno v:
SOJ Neurology and Neuroscience. 1
The possible ameliorative roles of the dipeptide carnosine with respect to Covid-19 viral infection and associated pathologies are discussed. In particular carnosine’s ability to suppress age-related changes in carbohydrate metabolism which normall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6620f428e86968026e72b1ee237839b7
https://doi.org/10.53902/sojnn.2021.01.000506
https://doi.org/10.53902/sojnn.2021.01.000506
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1868:119117
Carnosine is a naturally occurring dipeptide found in meat. Alternatively it can be formed through synthesis from the amino acids, β-alanine and L-histidine. Carnosine has long been advocated for use as an anti-oxidant and anti-glycating agent to fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff68ddf762e7376bf44e137eb6b014d
https://doi.org/10.1016/j.bbamcr.2021.119117
https://doi.org/10.1016/j.bbamcr.2021.119117
Autor:
Alan R. Hipkiss
Publikováno v:
Aging and Disease
Recent research shows that energy metabolism can strongly influence proteostasis and thereby affect onset of aging and related disease such as Parkinson's disease (PD). Changes in glycolytic and proteolytic activities (influenced by diet and developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86db836511242a5e5aee51b7ff486a15
http://europepmc.org/articles/PMC5440112
http://europepmc.org/articles/PMC5440112
Autor:
Alan R. Hipkiss
Publikováno v:
Online Journal of Neurology and Brain Disorders. 3
The scientific study of Emotional Intelligence (EI) in organizations has gained considerable research activity over recent years [1]. Simultaneously researchers have investigated and raised concerns about the appropriate way to measure EI in various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a1ee7db182f7cfacdcc3d465a8657ce
https://doi.org/10.32474/ojnbd.2019.03.000168
https://doi.org/10.32474/ojnbd.2019.03.000168
Autor:
Alan R. Hipkiss
Publikováno v:
Aging and Disease
Aging and much related dysfunction can be delayed by decreased glycolysis, however dysfunctional glycolysis appears to play a causative role in Alzheimer's disease (AD). It is proposed here that this apparent contradiction can be reconciled by sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648eb10111946f3e2c0aeaa79f38bc2f
https://pubmed.ncbi.nlm.nih.gov/31788344
https://pubmed.ncbi.nlm.nih.gov/31788344
Autor:
Alan R Hipkiss
Publikováno v:
Integrative Food, Nutrition and Metabolism. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb08e30ee7d450b35838383884efb2d4
https://doi.org/10.15761/ifnm.1000244
https://doi.org/10.15761/ifnm.1000244
Autor:
Barbora de Courten, Giancarlo Aldini, Estifanos Baye, Jozef Ukropec, Alan R. Hipkiss, Barbara Ukropcova
Publikováno v:
Amino Acids. 48:1131-1149
Obesity, type 2 diabetes (T2DM) and cardiovascular disease (CVD) are the most common preventable causes of morbidity and mortality worldwide. They represent major public health threat to our society. Increasing prevalence of obesity and T2DM contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8061fdcf763120a4b1a776247a35a9
https://doi.org/10.1007/s00726-016-2208-1
https://doi.org/10.1007/s00726-016-2208-1