Zobrazeno 1 - 10
of 376
pro vyhledávání: '"Alan R Hargens"'
Autor:
Joselito V Sayson, Alan R Hargens
Publikováno v:
Revista Cubana de Investigaciones Biomédicas, Vol 38, Iss 3 (2019)
Weakness and neuromuscular deconditioning of the anti-gravity spine muscles develop after 6-month missions in space. There is also a high incidence of herniated nucleus pulposus in cervical and lumbar discs with back pain post-flight. Prolonged micro
Externí odkaz:
https://doaj.org/article/4e6d1582a871493689925ed99599a6e7
Autor:
Suhas Rao Velichala, Ryan D. Kassel, Victoria Ly, Donald E. Watenpaugh, Stuart M. C. Lee, Brandon R. Macias, Alan R. Hargens
Publikováno v:
Life, Vol 14, Iss 7, p 793 (2024)
Microgravity in spaceflight produces headward fluid shifts which probably contribute to Spaceflight-Associated Neuro-Ocular Syndrome (SANS). Developing new methods to mitigate these shifts is crucial for preventing SANS. One possible strategy is the
Externí odkaz:
https://doaj.org/article/9d6e8822b0c847b4baa024c463b869fd
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Astronauts suffer from a loss of bone mass at a rate of 1.5% per month from lower regions of the body during the course of long-duration (>30 days) spaceflight, a phenomenon that poses important risks for returning crew. Conversely, a gain in bone ma
Externí odkaz:
https://doaj.org/article/3362a6bac6e04576a54601bb823de737
Autor:
Meenakshi Pandiarajan, Alan R. Hargens
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
This mini-review provides an updated summary of various analogs for adaptations of humans to the microgravity of space. Microgravity analogs discussed in this paper include dry immersion, wet immersion, unilateral lower-extremity limb suspension, hea
Externí odkaz:
https://doaj.org/article/527d20d6f1734ef38c5b6aec0ea87b37
Publikováno v:
Bone Reports, Vol 7, Iss C, Pp 57-62 (2017)
Previously our laboratory documented increases in calvaria bone volume and thickness in mice exposed to 15 days of spaceflight aboard the NASA Shuttle mission STS-131. However, the tissues were not processed for gene expression studies to determine w
Externí odkaz:
https://doaj.org/article/ae9f9c65d882455280b0977eed8e3991
Autor:
Jessica V. Jasien, Steven S. Laurie, Stuart M. C. Lee, David S. Martin, David T. Kemp, Douglas J. Ebert, Robert Ploutz-Snyder, Karina Marshall-Goebel, Irina V. Alferova, Ashot Sargsyan, Richard W. Danielson, Alan R. Hargens, Scott A. Dulchavsky, Michael B. Stenger, Brandon R. Macias
Publikováno v:
Journal of Applied Physiology. 133:721-731
Weightlessness induces a cephalad shift of blood and cerebrospinal fluid that may increase intracranial pressure (ICP) during spaceflight, whereas lower body negative pressure (LBNP) may provide an opportunity to caudally redistribute fluids and lowe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ac5258d4121822aa34575240e0fcf6
https://doi.org/10.1152/japplphysiol.00625.2021
https://doi.org/10.1152/japplphysiol.00625.2021
Autor:
Yang Sook Chun, Alan R. Hargens
Publikováno v:
Revista Cubana de Investigaciones Biomédicas, Vol 38, Iss 3 (2019)
Maintaining health in microgravity and overcoming environmental hazards such as cosmic radiation are essential for long-term space flight. Recent studies have focused on the involvement of hypoxia-inducible factor (HIF)-1 in altered gravity using cel
Externí odkaz:
https://doaj.org/article/e04bc41bd37c4ad7a278666e45a43227
Autor:
Lucas Dziesinski, Alan R. Hargens, Priya Nyayapati, Gabriel T.A. Johnson, Jeannie F. Bailey, Conor O'Neill, Jeffrey C. Lotz, Aaron Scheffler, Rebecca J. Crawford, Richard A. Scheuring, Douglas G. Chang
Publikováno v:
The Spine Journal. 22:197-206
Background Context For chronic low back pain, the causal mechanisms between pathological features from imaging and patient symptoms are unclear. For instance, disc herniations can often be present without symptoms. There remains a need for improved k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7605ad30af3ddd7ea6588a6f92a1d275
https://doi.org/10.1016/j.spinee.2021.07.021
https://doi.org/10.1016/j.spinee.2021.07.021
Autor:
Jamila H. Siamwala, Davina G. Moossazadeh, Timothy R. Macaulay, Rachel L. Becker, Rekha H. Hargens, Alan R. Hargens
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Hands may show early signs of aging with altered skin texture, skin permeability and vascular properties. In clinics, a hand volumeter is used to measure swelling of hands due to edema, carpal tunnel syndrome or drug interventions. The hand volume me
Externí odkaz:
https://doaj.org/article/ecb1f37149e742849bdbd20795cfbdf5
Autor:
David Martin, Scott A. Dulchavsky, Douglas J. Ebert, K A Zuj, Ashot E. Sargsyan, Brandon R. Macias, Philippe Arbeille, Alan R. Hargens, Steven S. Laurie, Stuart M. C. Lee, Michael B. Stenger
Publikováno v:
J Appl Physiol (1985)
Cephalad fluid shifts in space have been hypothesized to cause the spaceflight-associated neuro-ocular syndrome (SANS) by increasing the intracranial-ocular translaminal pressure gradient. Lower body negative pressure (LBNP) can be used to shift uppe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5f3efa1b1cd9e32d49ad1b78ee9439
https://doi.org/10.1152/japplphysiol.00231.2021
https://doi.org/10.1152/japplphysiol.00231.2021