Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alan P. Lewis"'
Autor:
Wing Ki Wong, Sarah A. Robinson, Alexander Bujotzek, Guy Georges, Alan P. Lewis, Jiye Shi, James Snowden, Bruck Taddese, Charlotte M. Deane
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Solving the structure of an antibody-antigen complex gives atomic level information of the interactions between an antibody and its antigen, but such structures are expensive and hard to obtain. Alternative experimental sources include epitope mappin
Externí odkaz:
https://doaj.org/article/efd55cb0505346a09833b01bd619abde
Autor:
Martin J. Scott, Amanda Jowett, Martin Orecchia, Peter Ertl, Larissa Ouro-Gnao, Julia Ticehurst, David Gower, John Yates, Katie Poulton, Carol Harris, Michael J. Mullin, Kathrine J. Smith, Alan P. Lewis, Nick Barton, Michael L. Washburn, Ruud de Wildt
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Complex cellular targets such as G protein-coupled receptors (GPCRs), ion channels, and other multi-transmembrane proteins represent a significant challenge for therapeutic antibody discovery, primarily because of poor stability of the target protein
Externí odkaz:
https://doaj.org/article/9568bbb2030349d68273fb8c36b14f92
Autor:
Nancy A. Pike, Bhaswati Roy, Cristina Cabrera-Mino, Nancy J. Halnon, Alan B. Lewis, Xingfeng Shao, Danny J. J. Wang, Rajesh Kumar
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 11, Iss 8, p 236 (2024)
(1) Introduction: Adolescents with complex congenital heart disease (CCHD) show brain tissue injuries in regions associated with cognitive deficits. Alteration in cerebral arterial perfusion (CAP), as measured by arterial transit time (ATT), may lead
Externí odkaz:
https://doaj.org/article/9b6406fbd80c46f79f6d0f91af456400
Autor:
Nancy A. Pike, Mary A. Woo, Marie K. Poulsen, Wendy Evangelista, Dylan Faire, Nancy J. Halnon, Alan B. Lewis, Rajesh Kumar
Publikováno v:
Frontiers in Pediatrics, Vol 4 (2016)
Introduction: Adolescents and young adults with congenital heart disease [CHD] show a range of memory deficits, which can dramatically impact their clinical outcomes and quality of life. However, few studies have identified predictors of these memory
Externí odkaz:
https://doaj.org/article/2a82f1756b79416aa87558f3735e6916
Autor:
Wiebke Wilkars, Zhiqiang Liu, Alan S Lewis, Travis R Stoub, Elena M Ramos, Nicola Brandt, Daniel A Nicholson, Dane M Chetkovich, Roland A Bender
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32181 (2012)
The functions of HCN channels in neurons depend critically on their subcellular localization, requiring fine-tuned machinery that regulates subcellular channel trafficking. Here we provide evidence that regulatory mechanisms governing axonal HCN chan
Externí odkaz:
https://doaj.org/article/a0d771e306784d8ea0299c899073be58
Publikováno v:
Molecular and Biochemical Parasitology. 42:241-246
Serum from mice hyperimmune to Plasmodium yoelii was used to screen a P. yoelii genomic DNA library. Antibodies selected from hyperimmune serum by λ gt11 clone J7 or raised against a specific fusion protein or peptide produced a punctate pattern of
Autor:
Alan P. Lewis
Publikováno v:
Molecular and Biochemical Parasitology. 39:285-288
Autor:
John F. Y. Brookfield, Alan P. Lewis
Publikováno v:
Molecular and General Genetics MGG. 208:506-510
The Drosophila melanogaster mobile DNA sequences P factors and P elements transpose at elevated rates when P strain males are mated to M strain females in a hybrid dysgenic cross (Engels 1983). Isofemale lines derived from such a cross were analysed
Autor:
Alan P. Lewis
Publikováno v:
Molecular and biochemical parasitology. 36(3)
The complete nucleotide sequence of the gene for the 230-kDa precursor to the major merozoite surface antigens (PMMSA) of Plasmodium yoelii YM has been determined. A single open reading frame of 5316 bp encodes a protein of calculated molecular mass
Autor:
James P. Bauer, Sarah L. Rader, Max E. Joffe, Wooseok Kwon, Juliana Quay, Leann Seanez, Chengwen Zhou, P. Jeffrey Conn, Alan S. Lewis
Publikováno v:
Biological Psychiatry Global Open Science, Vol 1, Iss 2, Pp 101-111 (2021)
Background: The anterior hippocampus of individuals with early psychosis or schizophrenia is hyperactive, as is the ventral hippocampus in many rodent models for schizophrenia risk. Mossy cells (MCs) of the ventral dentate gyrus (DG) densely project
Externí odkaz:
https://doaj.org/article/8a9ca9a844ee44ec836d967e7a3b4137