Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Alan O, Perantoni"'
Autor:
Heather M. Wojcik, Harold N. Lovvorn, Melinda Hollingshead, Janene Pierce, Howard Stotler, Andrew J. Murphy, Suzanne Borgel, Hannah M. Phelps, Hernan Correa, Alan O. Perantoni
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionWilms Tumor (WT), or nephroblastoma, is the most common pediatric kidney cancer. Most WTs display a “favorable” triphasic histology, in which the tumor is comprised of blastemal, stromal, and epithelial cell types. Blastemal predomina
Externí odkaz:
https://doaj.org/article/ea00302988104db4a573fde3beb50e09
Publikováno v:
Differentiation. 130:7-15
Fibroblast growth factors (Fgfs) have long been implicated in processes critical to embryonic development, such as cell survival, migration, and differentiation. Several mouse models of organ development ascribe a prosurvival requirement specifically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b707ce3ff310ab48028dd3ecff39908
https://doi.org/10.1016/j.diff.2022.12.001
https://doi.org/10.1016/j.diff.2022.12.001
Autor:
Richard R. Behringer, Robert G. McKinnell, Dimitri Viza, Alan O. Perantoni, Elizabeth J. Robertson, Sally L. Dunwoodie, Mark Lewandoski
Publikováno v:
Differentiation. 130:28-31
The International Society of Differentiation was born from the First International Conference on Cell Differentiation conceived by D.V. and held in Nice, France in 1971. The conference also resulted in the creation of the journal of the Society named
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d16463b7e4b50dd5fd35a787b6cbc8
https://doi.org/10.1016/j.diff.2022.12.003
https://doi.org/10.1016/j.diff.2022.12.003
Autor:
Shunsuke Tanigawa, Atsuhiro Taguchi, Nirmala Sharma, Alan O. Perantoni, Ryuichi Nishinakamura
Publikováno v:
Cell Reports, Vol 15, Iss 4, Pp 801-813 (2016)
Nephron progenitors in the embryonic kidney propagate while generating differentiated nephrons. However, in mice, the progenitors terminally differentiate shortly after birth. Here, we report a method for selectively expanding nephron progenitors in
Externí odkaz:
https://doaj.org/article/6658f82689084902920938fe6eb7c9a2
Publikováno v:
Stem Cell Reports, Vol 5, Iss 3, Pp 435-447 (2015)
Understanding the mechanisms responsible for nephrogenic stem cell preservation and commitment is fundamental to harnessing the potential of the metanephric mesenchyme (MM) for nephron regeneration. Accordingly, we established a culture model that pr
Externí odkaz:
https://doaj.org/article/977d3a35a00f4401a0e4a606ad0cc872
Autor:
Heather M. Wojcik, Harold N. Lovvorn, Melinda Hollingshead, Janene Pierce, Howard Stotler, Andrew J. Murphy, Suzanne Borgel, Hannah M. Phelps, Hernan Correa, Alan O. Perantoni
IntroductionWilms Tumor (WT), or nephroblastoma, is the most common pediatric kidney cancer. Most WTs display a “favorable” triphasic histology, in which the tumor is comprised of blastemal, stromal, and epithelial cell types. Blastemal predomina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703c2c0336d99bed27c1f404a6b4069d
https://doi.org/10.1101/2022.11.07.515473
https://doi.org/10.1101/2022.11.07.515473
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197356 (2018)
Transplacental viral and parasitic infections have been shown to initiate an innate response in the mammalian embryo by increasing the expression of pro-inflammatory cytokines such as interferon-gamma (Ifng). However, the developmental consequences o
Externí odkaz:
https://doaj.org/article/23e2630cdc464978943b28331e117aff
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006610 (2017)
To date, mutations within the coding region and translocations around the SOX9 gene both constitute the majority of genetic lesions underpinning human campomelic dysplasia (CD). While pathological coding-region mutations typically result in a non-fun
Externí odkaz:
https://doaj.org/article/a8d0fb3697ae406ba3ce59eb50139be3
Autor:
Andrew J. Murphy, Christian de Caestecker, Janene Pierce, Scott C. Boyle, Gregory D. Ayers, Zhiguo Zhao, Jaime M. Libes, Hernan Correa, Teagan Walter, Stacey S. Huppert, Alan O. Perantoni, Mark P. de Caestecker, Harold N. Lovvorn, III
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 12, Pp 1153-1163 (2012)
Hepatoblastoma, the most common pediatric liver cancer, consists of epithelial mixed embryonal/fetal (EMEF) and pure fetal histologic subtypes, with the latter exhibiting a more favorable prognosis. Few embryonal histology markers that yield insight
Externí odkaz:
https://doaj.org/article/0ca02d00ae4f45f28a4e012902e98800
Autor:
Harold N. Lovvorn, III, Jenifer Westrup, Shaun Opperman, Scott Boyle, Genbin Shit, James Anderson, Elizabeth J. Perlman, Alan O. Perantoni, Marcia Wills, Mark {ptde} Caestecker
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 7, Pp 589-600 (2007)
Wilms' tumors, or nephroblastomas, are thought to arise from abnormal postnatal retention and dysregulated differentiation of nephrogenic progenitor cells that originate as a condensed metanephric mesenchyme within embryonic kidneys. We have previous
Externí odkaz:
https://doaj.org/article/2fe33da8694f4ab8895d6f8fe9734cb5