Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Alan N. Hunt"'
Autor:
Alison Scott, Alan N. Hunt, Dominic J. Corkill, Nicholas J. White, Patricia C. Ryan, Anthony D. Postle, Lorin Roskos, Marlon Rebelatto, Mary Jane Hinrichs, Matthew J Robinson, Josquin A Nys, Matthew Sleeman
Granulocyte macrophage colony stimulating factor (GM-CSF) is a key participant in, and a clinical target for, the treatment of inflammatory diseases including rheumatoid arthritis (RA). Therapeutic inhibition of GM-CSF signalling using monoclonal ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f387d3995ba16db8e7128ba41dea8042
https://eprints.soton.ac.uk/452362/
https://eprints.soton.ac.uk/452362/
Autor:
Cecilia D'Angelo, Alan N. Hunt, Sabrina Rosset, Joost Brandsma, Grielof Koster, Anthony D. Postle
Publikováno v:
Coral Reefs. 38:1241-1253
Climate change-induced global warming threatens the survival of key ecosystems including shallow water coral reefs. Elevated temperatures can disrupt the normal physiological functioning of photosynthetic organisms by altering the fluidity and permea
Autor:
Tual Monfort, Pavlos G. Lagoudakis, Anthony D. Postle, Alan N. Hunt, Anagha Malur, Sumeet Mahajan, Mary Jane Thomassen
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Maintenance of tissue-specific organ lipid compositions characterizes mammalian lipid homeostasis. The lungs and liver synthesize mixed phosphatidylcholine (PC) molecular species that are subsequently tailored for function. The lungs progressively en
Autor:
David A. Johnston, Ella J. Baker, Alan N. Hunt, Wendy S. Smith, Suzanne E. Holmes, David J. Flavell, Grielof Koster, Sopsamorn U. Flavell
Triterpenoid saponins from Saponinum Album (SA) exert potent lytic effects on eukaryotic cell plasma membranes and, when used at sub-lytic concentrations, significantly augment the cytotoxicity of saporin-based immunotoxins (IT). To help elucidate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d3bf38e3952b57a6e47b072cc53b98
https://eprints.soton.ac.uk/406398/
https://eprints.soton.ac.uk/406398/
Autor:
Eric P. Achterberg, Alan N. Hunt, Jörg Wiedenmann, François-Eric Legiret, Cecilia D'Angelo, Edward G. Smith, Anthony D. Postle
Publikováno v:
Nature Climate Change. 3:160-164
Mass coral bleaching, resulting from the breakdown of coral-algal symbiosis has been identified as the most severe threat to coral reef survival on a global scale. Regionally, nutrient enrichment of reef waters is often associated with a significant
Autor:
Jeffrey A. Whitsett, Anthony D. Postle, Machiko Ikegami, Susan E. Wert, Alan N. Hunt, Valérie Besnard, Laurent Plantier, Yan Xu
Publikováno v:
Journal of Biological Chemistry. 287:10099-10114
Pulmonary inflammation is associated with altered lipid synthesis and clearance related to diabetes, obesity, and various inherited metabolic disorders. In many tissues, lipogenesis is regulated at the transcriptional level by the activity of sterol-
Autor:
Suzanne Jackowski, Robert V. Law, Oscar Ces, Christophe Plisson, Alan N. Hunt, Sarra C. Sebai, Christine A. Parker, George S. Attard, M. Baciu, James A. Clarke, Antony D. Gee, Richard H. Templer, Gemma C. Shearman, Xavier Mulet
Publikováno v:
Biochemical Society Transactions. 35:498-501
The nature of the bilayer motif coupled with the ability of lipids and proteins to diffuse freely through this structure is crucial to the viability of cells and their ability to compartmentalize domains contained therein. It seems surprising to find
Autor:
Anthony D. Postle, Alan N. Hunt
Publikováno v:
Methods. 39:104-111
Mammalian cell lipid analyses using tandem electrospray ionization mass spectrometry, in conjunction with stable isotope labeling, permit unparalleled access to membrane phospholipid molecular species compositions and turnover. Lipidomic data from is