Zobrazeno 1 - 10
of 263
pro vyhledávání: '"Alan N, Houghton"'
Autor:
Alan N Houghton, Jedd D Wolchok, Taha Merghoub, Daniel Hirschhorn, Linda Hamadene, Yacine Marouf, Allison B Warner, Mariam M George, Nicholas J Ceglia
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/856c991276d94616af2a5da1209a1193
Autor:
Daniel Hirschhorn, Allison Betof Warner, Rachana Maniyar, Andrew Chow, Levi M.B. Mangarin, Adam D. Cohen, Linda Hamadene, Gabrielle A. Rizzuto, Sadna Budhu, Nathan Suek, Cailian Liu, Alan N. Houghton, Taha Merghoub, Jedd D. Wolchok
Publikováno v:
JCI Insight, Vol 6, Iss 20 (2021)
Only a subset of cancer patients responds to checkpoint blockade inhibition in the clinic. Strategies to overcome resistance are promising areas of investigation. Targeting glucocorticoid-induced tumor necrosis factor receptor–related protein (GITR
Externí odkaz:
https://doaj.org/article/e630bf7834ce472b9967dd8f1a880b48
Autor:
Jedd D. Wolchok, Taha Merghoub, Alan N. Houghton, Xia Yang, Hong Zhong, Adam Cohen, Nicole Malandro, Campbell Bryson, Cailian Liu, Sadna Budhu, David A. Schaer
PDF file - 84K, Percentage of CD4+Foxp3+ Tregs in IgG vs DTA-1 treated tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3fc51fde8f53873febd317d76bb8dd8
https://doi.org/10.1158/2326-6066.22535843.v1
https://doi.org/10.1158/2326-6066.22535843.v1
Autor:
Jedd D. Wolchok, Taha Merghoub, Alan N. Houghton, Xia Yang, Hong Zhong, Adam Cohen, Nicole Malandro, Campbell Bryson, Cailian Liu, Sadna Budhu, David A. Schaer
PDF file - 143K, Foxp3 loss in Tregs is tumor and DTA-1 dose dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6797bf04ea04a40e0d2d70aae72ceefa
https://doi.org/10.1158/2326-6066.22535846
https://doi.org/10.1158/2326-6066.22535846
Autor:
Jedd D. Wolchok, Taha Merghoub, Alan N. Houghton, Xia Yang, Hong Zhong, Adam Cohen, Nicole Malandro, Campbell Bryson, Cailian Liu, Sadna Budhu, David A. Schaer
PDF file - 48K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92da90883bb385af050d8d9c41be5fc3
https://doi.org/10.1158/2326-6066.22535840.v1
https://doi.org/10.1158/2326-6066.22535840.v1
Autor:
Jedd D. Wolchok, Taha Merghoub, Alan N. Houghton, Xia Yang, Hong Zhong, Adam Cohen, Nicole Malandro, Campbell Bryson, Cailian Liu, Sadna Budhu, David A. Schaer
Ligation of GITR (glucocorticoid-induced TNF receptor-related gene, or TNFRSF18) by agonist antibody has recently entered into early-phase clinical trials for the treatment of advanced malignancies. Although the ability of GITR modulation to induce t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18ce48bcaa8fde54e58fe3e69611bddb
https://doi.org/10.1158/2326-6066.c.6547961.v1
https://doi.org/10.1158/2326-6066.c.6547961.v1
Autor:
James W. Young, Jianda Yuan, Glenn Heller, Paul B. Chapman, Alan N. Houghton, Jedd D. Wolchock, Katherine S. Panageas, David J. Chung, Maria-Angeles de Cos, Gudrun Ratzinger, Marco Rossi, Emanuela Romano
Purpose: We compared the efficacy of human Langerhans cells (LC) as tumor immunogens in vivo with monocyte-derived dendritic cells (moDC) and investigated how interleukin 15 (IL15) supports optimal DC-stimulated antitumor immunity.Experimental Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0dccddfa6fe81d80af41c9d40fa3c15
https://doi.org/10.1158/1078-0432.c.6519468
https://doi.org/10.1158/1078-0432.c.6519468
Autor:
James W. Young, Jianda Yuan, Glenn Heller, Paul B. Chapman, Alan N. Houghton, Jedd D. Wolchock, Katherine S. Panageas, David J. Chung, Maria-Angeles de Cos, Gudrun Ratzinger, Marco Rossi, Emanuela Romano
Supplementary Figures S1-S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fc951a086e34ded8b65cde31b59e83
https://doi.org/10.1158/1078-0432.22442805
https://doi.org/10.1158/1078-0432.22442805
Autor:
Jedd D. Wolchok, Taha Merghoub, Alan N. Houghton, Eric G. Pamer, John J. Lazarus, Gabrielle A. Rizzuto, Francesca Avogadri, Daniel Hirschhorn-Cymerman, Czrina Cortez, Shigehisa Kitano, Tobias M. Hohl, Alexander M. Lesokhin
PDF file - 1.8MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9551f83db4c5caa91606d8e1f32c79c9
https://doi.org/10.1158/0008-5472.22391825
https://doi.org/10.1158/0008-5472.22391825
Autor:
Alan N. Houghton, Jedd D. Wolchok, Stephanie Terzulli, Taha Merghoub, Shimon Sakaguchi, Michael Curran, Adam D. Cohen, Manuel E. Engelhorn, Cailian Liu, Yun Lin, Fei Duan
Supplementary Figure Legends 1-4 from Immune Rejection of Mouse Tumors Expressing Mutated Self
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424670033f93744445a854fc8380d9c0
https://doi.org/10.1158/0008-5472.22381101.v1
https://doi.org/10.1158/0008-5472.22381101.v1