Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alan MacIntyre"'
Autor:
Paul G Shiels, Liane M McGlynn, Alan MacIntyre, Paul C D Johnson, G David Batty, Harry Burns, Jonathan Cavanagh, Kevin A Deans, Ian Ford, Alex McConnachie, Agnes McGinty, Jennifer S McLean, Keith Millar, Naveed Sattar, Carol Tannahill, Yoga N Velupillai, Chris J Packard
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22521 (2011)
It has previously been hypothesized that lower socio-economic status can accelerate biological ageing, and predispose to early onset of disease. This study investigated the association of socio-economic and lifestyle factors, as well as traditional a
Externí odkaz:
https://doaj.org/article/8496f7f55821490cb33b0ae42eee5f8e
Autor:
Christian Koppelstaetter, Alan MacIntyre, David Russell, Liane M. McGlynn, R. W. Davies, Paul G. Shiels, Kathrin Eller, Alasdair I. MacDonald
Publikováno v:
Rejuvenation Research. 16:11-20
Pathfinder cells (PCs) are a novel class of adult-derived cells that facilitate functional repair of host tissue. We used rat PCs to demonstrate that they enable the functional mitigation of ischemia reperfusion (I/R) injury in a mouse model of renal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1e14c7c878863a64639d6f125d41b7
https://doi.org/10.1089/rej.2012.1350
https://doi.org/10.1089/rej.2012.1350
Autor:
Karen S. Stevenson, R. Wayne Davies, Murali Subramaniam, Anthony Dorling, Alan MacIntyre, Anthony P. Payne, Liane M. McGlynn, Daxin Chen, Paul Montague, Paul G. Shiels, W.D. George, Rawiya Charif
Publikováno v:
Rejuvenation Research. 14:163-171
We demonstrate that intravenous delivery of human, or rat, pancreas-derived pathfinder (PDP) cells can totally regenerate critically damaged adult tissue and restore normal function across a species barrier. We have used a mouse model of streptozotoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caad94c591f7d688ba5eb1b60cc54db4
https://doi.org/10.1089/rej.2010.1099
https://doi.org/10.1089/rej.2010.1099
Autor:
Alan MacIntyre, Vladimira Moulisova, Dagmara McGuinness, Paul G. Shiels, Diana F. Anthony, Jacqueline Thomson, R. Wayne Davies, Alasdair I. MacDonald, Abhijeet Nag
Publikováno v:
Rejuvenation research. 19(3)
Pathfinder cells (PCs), a novel cell type derived from the pancreas of adult rats, have been demonstrated to stimulate recovery of tissue structure and function in two animal models of acute tissue damage to date-streptozotocin (STZ)-induced diabetes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e663d1c650c60893b8b0b3d718c9b27
https://pubmed.ncbi.nlm.nih.gov/26414011
https://pubmed.ncbi.nlm.nih.gov/26414011
Autor:
John M. Starr, K. Lamb, Ian J. Deary, Alan MacIntyre, K. Radhakrishnan, Sarah E. Harris, Lawrence J. Whalley, Paul G. Shiels
Publikováno v:
Neuroscience Letters. 406:260-264
Telomeres are nucleo-protein complexes that protect the ends of chromosomes. The telomeric DNA component shortens each time a somatic cell replicates, eventually leading to cell senescence. Telomere length has been associated with morbidity and morta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6bddd922cb057a83159a661440dae5
https://doi.org/10.1016/j.neulet.2006.07.055
https://doi.org/10.1016/j.neulet.2006.07.055
Autor:
Alan MacIntyre, S. Zino, David B. Kingsmore, W.D. George, N. Ashraf, Anthony P. Payne, Paul G. Shiels
Publikováno v:
British Journal of Cancer
Sirtuins are genes implicated in cellular and organismal ageing. Consequently, they are speculated to be involved in diseases of ageing including cancer. Various cancers with widely differing prognosis have been shown to have differing and characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde441a3c07baaa4fa142d3c0d91fb17
https://doi.org/10.1038/sj.bjc.6603384
https://doi.org/10.1038/sj.bjc.6603384
Autor:
Agnes McGinty, Yoga N. Velupillai, Alan MacIntyre, Dagmara McGuinness, Liane M. McGlynn, Alex McConnachie, Naveed Sattar, Jennifer S. McLean, Paul G. Shiels, Paul C. D. Johnson, G. David Batty, Kevin A. Deans, Jonathan Cavanagh, Harry Burns, Ian Ford, Chris J. Packard, Carol Tannahill, Keith Millar
Publikováno v:
International journal of epidemiology. 41(1)
Background: Epigenetic programming and epigenetic mechanisms driven by environmental factors are thought to play an important role in human health and ageing. Global DNA methylation has been postulated as an epigenetic marker for epidemiological stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b1ecbe63e5dbae76ac0add75b8e342
https://pubmed.ncbi.nlm.nih.gov/22253320
https://pubmed.ncbi.nlm.nih.gov/22253320
Autor:
Alex McConnachie, Chris J. Packard, Agnes McGinty, Yoga N. Velupillai, G. David Batty, Paul C. D. Johnson, Liane M. McGlynn, Paul G. Shiels, Kevin A. Deans, Alan MacIntyre, Carol Tannahill, Naveed Sattar, Keith Millar, Harry Burns, Ian Ford, Jennifer S. McLean, Jonathan Cavanagh
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 7, p e22521 (2011)
PLoS ONE, Vol 6, Iss 7, p e22521 (2011)
peer-reviewed Background: It has previously been hypothesized that lower socio-economic status can accelerate biological ageing, and predispose to early onset of disease. This study investigated the association of socio-economic and lifestyle factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbfd2b8d2f511d28460392779ba3db81
http://europepmc.org/articles/PMC3144896
http://europepmc.org/articles/PMC3144896
Simvastatin inhibits lymphocyte function in normal subjects and patients with cardiovascular disease
Autor:
Alan G. Jardine, Dianne Z. Hillyard, Alan MacIntyre, Maurizio Panarelli, Angus J.M. Cameron, Paul G. Shiels, Jacqueline Thomson, Kenneth J. McDonald
Publikováno v:
Atherosclerosis. 175(2)
HMG-CoA reductase inhibitors (statins) block the mevalonate pathway, preventing biosynthesis of cholesterol and isoprenoids. We investigated the effect of simvastatin on lymphocytes from normal human subjects and cardiovascular disease patients in or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ccd558ee70310f7659421c936235cd
https://pubmed.ncbi.nlm.nih.gov/15262187
https://pubmed.ncbi.nlm.nih.gov/15262187
Publikováno v:
Clinical Science. 102:8P-8P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cc3466539909993e011e7af7e75e75c
https://doi.org/10.1042/cs102008pa
https://doi.org/10.1042/cs102008pa