Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Alan M. O'Neill"'
Autor:
Teruaki Nakatsuji, Samantha L. Brinton, Kellen J. Cavagnero, Alan M. O’Neill, Yang Chen, Tatsuya Dokoshi, Anna M. Butcher, Olive C. Osuoji, Faiza Shafiq, Josh L. Espinoza, Christopher L. Dupont, Tissa R. Hata, Richard L. Gallo
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112494- (2023)
Summary: During inflammation, the skin deploys antimicrobial peptides (AMPs) yet during allergic inflammation it becomes more susceptible to Staphylococcus aureus. To understand this contradiction, single-cell sequencing of Il4ra−/− mice combined
Externí odkaz:
https://doaj.org/article/c523e643008445ddb28c15744b1f3886
Autor:
Alan M. O’Neill, Richard L. Gallo
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-16 (2018)
Abstract Acne is one of the most common skin diseases worldwide and results in major health care costs and significant morbidity to severely affected individuals. However, the pathophysiology of this disorder is not well understood. Host-microbiome i
Externí odkaz:
https://doaj.org/article/ec9e9132885d41ff8fe1b71a4fe4f73d
Publikováno v:
mBio, Vol 7, Iss 3 (2016)
Externí odkaz:
https://doaj.org/article/14a65166807f40328d644f0148111c3a
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT As key components of innate immune defense, macrophages are essential in controlling bacterial pathogens, including group A Streptococcus (GAS). Despite this, only a limited number of studies have analyzed the recovery of GAS from within hum
Externí odkaz:
https://doaj.org/article/ffab9758c9e641c7be7569313cf1184d
Autor:
Alan M. O’Neill, Marc C. Liggins, Jason S. Seidman, Tran H. Do, Fengwu Li, Kellen J. Cavagnero, Tatsuya Dokoshi, Joyce Y. Cheng, Faiza Shafiq, Tissa R. Hata, Johann E. Gudjonsson, Robert L. Modlin, Richard L. Gallo
Publikováno v:
Sci Transl Med
Science translational medicine, vol 14, iss 632
Science translational medicine, vol 14, iss 632
Innate immune defense against deep tissue infection by Staphylococcus aureus is orchestrated by fibroblasts that become antimicrobial when triggered to differentiate into adipocytes. However, the role of this process in noninfectious human diseases i
Autor:
Alan M. O’Neill, Robert H. Mills, Kate A. Worthing, Kit Pogliano, Dominic McGrosso, Richard L. Gallo, David Gonzalez, Fengwu Li, Nikhil Nitin Kulkarni, Gayathri Kalla, Teruaki Nakatsuji, Jacqueline M. Norris, Joe Pogliano, Joyce Y. Cheng
Publikováno v:
eLife, Vol 10 (2021)
Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is an important emerging zoonotic pathogen that causes severe skin infections. To combat infections from drug-resistant bacteria, the transplantation of commensal antimicrobial bacteria as
Autor:
Alan M. O’Neill, Kate A. Worthing, Nikhil Nitin Kulkarni, Kit Pogliano, Dominic McGrosso, Joyce Y. Cheng, Jacqueline M. Norris, Teruaki Nakatsuji, Robert H. Mills, Gayathri Kalla, David Gonzalez, Joe Pogliano, Fengwu Li, Richard L. Gallo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65afefa58eb76cc5284db8f3bc57d835
https://doi.org/10.7554/elife.66793.sa2
https://doi.org/10.7554/elife.66793.sa2
Autor:
Richard L. Gallo, Tatsuya Dokoshi, Alan M. O’Neill, Elizabeth Wei Chia Luo, Nikhil Nitin Kulkarni, Gerard C. L. Wong
Publikováno v:
The Journal of Biological Chemistry
The Journal of biological chemistry, vol 297, iss 1
The Journal of biological chemistry, vol 297, iss 1
Cathelicidins such as the human 37-amino acid peptide (LL-37) are peptides that not only potently kill microbes but also trigger inflammation by enabling immune recognition of endogenous nucleic acids. Here, a detailed structure-function analysis of
Autor:
Richard L. Gallo, Robert H. Mills, Kate A. Worthing, Nikhil Kulkarni, T. Nakatsuji, David Gonzalez, Alan M. O’Neill, Fengwu Li, Joyce Y. Cheng, Jacqueline M. Norris
Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is an important emerging zoonotic pathogen that causes severe skin infections. To combat infections from drug-resistant bacteria, the transplantation of commensal antimicrobial bacteria as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49d5e44ad7f77b48322c69675720cf00
https://doi.org/10.1101/2021.03.08.432323
https://doi.org/10.1101/2021.03.08.432323
Autor:
Christopher Churas, Lisa Miorin, Dexter Pratt, Anshu P. Gounder, Aaron L. Oom, Laura Martin-Sancho, Sumit K. Chanda, Judd F. Hultquist, Sophie Liu, Courtney Nguyen, Max W. Chang, Ariel Rodriguez-Frandsen, Trey Ideker, Alan M. O’Neill, Matthew Urbanowski, Yuan Pu, Megan L. Shaw, Sara Brin Rosenthal, John C. Guatelli, Paul D. De Jesus, Charlotte A. Stoneham, Christopher Benner, Mary K. Lewinski, Matthew B. Frieman, Lars Pache, Adolfo García-Sastre, Xin Yin
Publikováno v:
bioRxiv
A deficient interferon response to SARS-CoV-2 infection has been implicated as a determinant of severe COVID-19. To identify the molecular effectors that govern interferon control of SARS-CoV-2 infection, we conducted a large-scale gain-of-function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdb27efac76461cbaf3aeed7ee78337
https://europepmc.org/articles/PMC7536870/
https://europepmc.org/articles/PMC7536870/