Výsledky vyhledávání - "Alan M. Kook"

Application of 19 F time-domain NMR to measure content in fluorine-containing drug products

Autor: Maria Victoria Silva Elipe, Karthik Nagapudi, Alan M. Kook, Lan Li, Chen Peng, Carlos Cobas, Isaac Iglesias

Publikováno v: Magnetic Resonance in Chemistry. 54:531-538

It is necessary to show that the active content in the dosage form of drugs is within a certain narrow range of the label claim. In case of fluorinated drugs, the active content can be measured by high field solid state NMR because the excipients lac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6762fc41e1bcfa7e4fffabf48b6668e
https://doi.org/10.1002/mrc.4223

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Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products

Autor: Maria Victoria, Silva Elipe, Lan, Li, Karthik, Nagapudi, Alan M, Kook, Carlos, Cobas, Isaac, Iglesias, Chen, Peng

Publikováno v: Journal of visualized experiments : JoVE. (126)

Here, we describe a protocol developed by our group that uses low-field fluorine-19 ((19)F) time-domain (TD) nuclear magnetic resonance (NMR) to measure the average content of fluorinated drugs in their formulated drug product forms: tablets or capsu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5499bfa7b61b7259e586cdeaa63f9804
https://pubmed.ncbi.nlm.nih.gov/28872126

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Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products

Autor: Isaac Iglesias, Alan M. Kook, Chen Peng, Karthik Nagapudi, Maria Victoria Silva Elipe, Carlos Cobas, Lan Li

Publikováno v: Journal of Visualized Experiments.

Here, we describe a protocol developed by our group that uses low-field fluorine-19 (19F) time-domain (TD) nuclear magnetic resonance (NMR) to measure the average content of fluorinated drugs in their formulated drug product forms: tablets or capsule

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3185b2783ff66c651e03ced7207dc2a
https://doi.org/10.3791/55850-v

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Solution dynamics of tin and lead iron carbonyl compounds and the solid state structure of [Et4N]2[Sn{Fe2(CO)8}{Fe(CO)4}2]

Autor: Juanita M. Cassidy, Alan M. Kook, Kenton H. Whitmire

Publikováno v: Journal of Organometallic Chemistry. 456:61-70

The dynamic rearrangement processes of CO ligands on the Main Group-iron carbonyl compounds, E[Fe2(CO)8]2 (Ia, E  Pb), [Et4N]2[E{Fe2(CO)8}{Fe(CO)4}2]([Et4N]2[IIa], E  Pb; [Et4N]2[IIb], E  Sn) and [Et4N]2[Pb{Fe(CO)4}3] ([Et4N]2[IIIa], E  P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd085ecf45ca7986cf96192ddd5fa826
https://doi.org/10.1016/0022-328x(93)83318-p

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ChemInform Abstract: Synthesis and Characterization of a Series of 5H-Benzo(a)phenoxazin-5- one Derivatives as Potential Antiviral/Antitumor Agents

Autor: Alan M. Kook, Kanti G. Bhansali

Publikováno v: ChemInform. 24

A series of 1,2-benzo-3-phenoxazone also known as 5H-benzo [a]-phenoxazin-5-one (1a-1c) were synthesized and characterized by 1-and 2-D nmr, mass spectrometry and computer simulation on readily available, inexpensive software. It is proposed that the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0de442a621dcc24577bb0e5434bb3871
https://doi.org/10.1002/chin.199337250

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Electron self-exchange study of the coordination-number-invariant pentacoordinate copper(I/II) couple [CuI,II((5-meimidh)2DAP)]+/2+

Autor: Alan M. Kook, W. Robert Scheidt, Carmen. Bergman, Lon J. Wilson, David M. Stanbury, Jorge A. Gonzalez, Theodore D. Brennan, DeAnna K. Coggin

Publikováno v: Inorganic Chemistry. 30:1125-1134

The electron self-exchange rate of the [Cu I,II ((5-MeimidH) 2 DAP)] +/2+ cation coupled has been determined in CD 3 CN, as a function of temperature, by dynamic NMR line-broadening techniques

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0022f3e5d487690ba0b29daf1e16d4f0
https://doi.org/10.1021/ic00005a045

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Ligand dynamics in pentacoordinate copper(I) and zinc(II) complexes

Autor: Alan M. Kook, Lon J. Wilson, Jorge A. Gonzalez, DeAnna K. Coggin, David M. Stanbury

Publikováno v: Inorganic Chemistry. 30:1115-1125

Two new pentacoordinate zinc(II) and copper(I) complexes of the pentadentate ligand ((5-MeimidH) 2 DAP) have been prepared and studied as their BF 4 − salts. The primary coordination sphere of each compound is composed of a central pyridine nitroge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75289a56ef3567ad872d43a5fab17c17
https://doi.org/10.1021/ic00005a044

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On deuterium-labeling studies for probing rhodium-catalyzed hydroboration reactions

Autor: Alan M. Kook, Kevin Burgess, Wilfred A. van der Donk

Publikováno v: The Journal of Organic Chemistry. 56:2949-2951

Reactions of deuteriocatecholborane (C 6 H 4 -O 2 BD) with alkenes in the presence of rhodium (+1) complexes have been reinvestigated. Distributions of label in the products differ significantly from those reported previously, and alternative rationa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ae35919ffc66191c237868def4d5108
https://doi.org/10.1021/jo00009a002

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