Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Alan M. Gonzalez-Suarez"'
Autor:
Jose M. de Hoyos-Vega, Xi Yu, Alan M. Gonzalez-Suarez, Sisi Chen, Arnaldo Mercado-Perez, Eugene Krueger, Jeric Hernandez, Yaroslav Fedyshyn, Brooke R. Druliner, David R. Linden, Arthur Beyder, Alexander Revzin
Publikováno v:
Microsystems & Nanoengineering, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract The intestinal lumen is filled with diverse chemical and physical stimuli. Intestinal epithelial cells sense these stimuli and signal to enteric neurons which coordinate a range of physiologic processes required for normal digestive tract fu
Externí odkaz:
https://doaj.org/article/8988d01fb51a42e7bd786a15be570271
Autor:
Kihak Gwon, Daheui Choi, José M. de Hoyos-Vega, Harihara Baskaran, Alan M. Gonzalez-Suarez, Seonhwa Lee, Hye Jin Hong, Kianna M. Nguyen, Ether Dharmesh, Go Sugahara, Yuji Ishida, Takeshi Saito, Gulnaz Stybayeva, Alexander Revzin
Publikováno v:
Bioactive Materials, Vol 28, Iss , Pp 183-195 (2023)
The ability to maintain functional hepatocytes has important implications for bioartificial liver development, cell-based therapies, drug screening, and tissue engineering. Several approaches can be used to restore hepatocyte function in vitro, inclu
Externí odkaz:
https://doaj.org/article/249a633d3371400dad06b02aeb3413a6
Autor:
Daheui Choi, Alan M. Gonzalez‐Suarez, Mihai G. Dumbrava, Michael Medlyn, Jose M. deHoyos‐Vega, Frank Cichocki, Jeffrey S. Miller, Li Ding, Mojun Zhu, Gulnaz Stybayeva, Alexandre Gaspar‐Maia, Daniel D. Billadeau, Wen Wee Ma, Alexander Revzin
Publikováno v:
Advanced Science, Vol 11, Iss 5, Pp n/a-n/a (2024)
Abstract Patient‐derived cancer organoids (PDOs) hold considerable promise for personalizing therapy selection and improving patient outcomes. However, it is challenging to generate PDOs in sufficient numbers to test therapies in standard culture p
Externí odkaz:
https://doaj.org/article/8bace5ec4db746318ee3c8614e155c51
Autor:
Mercedes Taroncher, Alan M. Gonzalez-Suarez, Kihak Gwon, Samuel Romero, Angel D. Reyes-Figueroa, Yelko Rodríguez-Carrasco, María-José Ruiz, Gulnaz Stybayeva, Alexander Revzin, Jose M. de Hoyos-Vega
Publikováno v:
Cells, Vol 13, Iss 11, p 900 (2024)
The Fusarium fungi is found in cereals and feedstuffs and may produce mycotoxins, which are secondary metabolites, such as the T-2 toxin (T-2). In this work, we explored the hepatotoxicity of T-2 using microfluidic 3D hepatic cultures. The objectives
Externí odkaz:
https://doaj.org/article/5653ff004457445fb78059f1878ab28b
Autor:
Kihak Gwon, Hye Jin Hong, Alan M. Gonzalez-Suarez, Michael Q. Slama, Daheui Choi, Jinkee Hong, Harihara Baskaran, Gulnaz Stybayeva, Quinn P. Peterson, Alexander Revzin
Publikováno v:
Bioactive Materials, Vol 15, Iss , Pp 1-14 (2022)
Human pluripotent stem cells (hPSC) hold considerable promise as a source of adult cells for treatment of diseases ranging from diabetes to liver failure. Some of the challenges that limit the clinical/translational impact of hPSCs are high cost and
Externí odkaz:
https://doaj.org/article/82e304db50db4772875bb07418f55833
Autor:
Xu Zhang, Vesselina M. Pearsall, Chase M. Carver, Elizabeth J. Atkinson, Benjamin D. S. Clarkson, Ethan M. Grund, Michelle Baez-Faria, Kevin D. Pavelko, Jennifer M. Kachergus, Thomas A. White, Renee K. Johnson, Courtney S. Malo, Alan M. Gonzalez-Suarez, Katayoun Ayasoufi, Kurt O. Johnson, Zachariah P. Tritz, Cori E. Fain, Roman H. Khadka, Mikolaj Ogrodnik, Diana Jurk, Yi Zhu, Tamara Tchkonia, Alexander Revzin, James L. Kirkland, Aaron J. Johnson, Charles L. Howe, E. Aubrey Thompson, Nathan K. LeBrasseur, Marissa J. Schafer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The authors discovered that proinflammatory senescent myeloid cells may recruit peripheral immune cells in the aged mouse brain. Their findings implicate senescent cell clearance as a strategy to counter aged brain inflammation and cognitive decline.
Externí odkaz:
https://doaj.org/article/563782268a174f9491ef229d9fd5e5e9
Autor:
Pouria Fattahi, Jose M. de Hoyos-Vega, Jong Hoon Choi, Caden D. Duffy, Alan M. Gonzalez-Suarez, Yuji Ishida, Kianna M. Nguyen, Kihak Gwon, Quinn P. Peterson, Takeshi Saito, Gulnaz Stybayeva, Alexander Revzin
Publikováno v:
Cells, Vol 12, Iss 15, p 1982 (2023)
Human pluripotent stem cells (hPSCs) are capable of unlimited proliferation and can undergo differentiation to give rise to cells and tissues of the three primary germ layers. While directing lineage selection of hPSCs has been an active area of rese
Externí odkaz:
https://doaj.org/article/a37baaa26ed144c583c718d6c96e880b
Autor:
Pouria Fattahi, Ali Rahimian, Michael Q. Slama, Kihak Gwon, Alan M. Gonzalez-Suarez, Jadon Wolf, Harihara Baskaran, Caden D. Duffy, Gulnaz Stybayeva, Quinn P. Peterson, Alexander Revzin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Cellular therapies based on human pluripotent stem cells (hPSCs) offer considerable promise for treating numerous diseases including diabetes and end stage liver failure. Stem cell spheroids may be cultured in stirred bioreactors to scale up
Externí odkaz:
https://doaj.org/article/53e0a7662aba4e918a6dcc5423f60520
Publikováno v:
Clinical and Experimental Otorhinolaryngology, Vol 14, Iss 1, Pp 29-42 (2021)
Microfluidic systems can be used to control picoliter to microliter volumes in ways not possible with other methods of fluid handling. In recent years, the field of microfluidics has grown rapidly, with microfluidic devices offering possibilities to
Externí odkaz:
https://doaj.org/article/c51b018853834a0294e4dfff58d96f0b
Publikováno v:
Biosensors, Vol 12, Iss 12, p 1160 (2022)
We describe a control system for operating valve-enabled microfluidic devices and leverage this control system to carry out a complex workflow of plasma separation from 8 μL of whole blood followed by on-chip mixing of plasma with assay reagents for
Externí odkaz:
https://doaj.org/article/98905ae2bc274b4eb2826e0213512209