Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Alan M Williams"'
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Akademický článek
Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells.
Autor: Alan M Williams, Yaakov Maman, Jukka Alinikula, David G Schatz
Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0149146 (2016)
The activation induced cytosine deaminase (AID) mediates diversification of B cell immunoglobulin genes by the three distinct yet related processes of somatic hypermutation (SHM), class switch recombination (CSR), and gene conversion (GCV). SHM occur
Externí odkaz: https://doaj.org/article/da2821501e8f40e6b203a4335d12800f
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7
A Novel Stealth Strategy That Activates Adoptively Transferred Allogeneic Immune Cells and Avoids Rejection for Off-the-Shelf Cell-Based Cancer Therapy
Autor: Ken Hayama, Ryan Bjordahl, Nicholas Brookhouser, Lauren Fong, Jode P Goodridge, Berhan Mandefro, Brian Groff, Bahram Valamehr, Karl-Johan Malmberg, Ramzey Abujarour, Alan M Williams, Thomas H. Lee, Maksim Mamonkin, Quirin Hammer, Rina M Mbofung, Yijia Pan
Publikováno v: Blood. 138:4800-4800
Chimeric antigen receptor (CAR) T-cell therapies have revolutionized the treatment of hematologic malignancies, however, logistical complexities associated with patient-specific CAR T-cell therapies often limit broad accessibility to patients. Many o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47b19348303e9c6495d4c4d5391c1ffc
https://doi.org/10.1182/blood-2021-153614
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8
Off-the-Shelf, iPSC-Derived CAR-NK Cells Multiplexed-Engineered for the Avoidance of Allogeneic Host Immune Cell Rejection
Autor: Alan M Williams, Rina M Mbofung, Sajid Mahmood, Greg Bonello, Ryan Bjordahl, Thomas Dailey, Yijia Pan, Thomas H. Lee, Ketan Mathavan, Jode P Goodridge, Ken Hayama, Sonia Reyes, Brian Groff, Karl-Johan Malmberg, Bahram Valamehr, Quirin Hammer
Publikováno v: Blood. 138:2795-2795
Allogeneic off-the-shelf cell therapies offer distinct advantages over conventional autologous cell therapies in terms of scaled manufacturing, on-demand availability and optimization of cellular starting material. A unique consideration in the use o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f74b1c8dec456dd8513ae996cbff04ec
https://doi.org/10.1182/blood-2021-153484
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9
Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells
Autor: Yaakov Maman, David G. Schatz, Jukka Alinikula, Alan M. Williams
Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0149146 (2016)
PLoS ONE
The activation induced cytosine deaminase (AID) mediates diversification of B cell immunoglobulin genes by the three distinct yet related processes of somatic hypermutation (SHM), class switch recombination (CSR), and gene conversion (GCV). SHM occur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ced0832c29b4e686d2c82d86139455
http://juuli.fi/Record/0253328116
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10
The C-Terminal Domain of Yeast High Mobility Group Protein HMO1 Mediates Lateral Protein Accretion and In-Phase DNA Bending
Autor: Anne Grove, Lijuan Xiao, Alan M. Williams
Publikováno v: Biochemistry. 49:4051-4059
The Saccharomyces cerevisiae high mobility group protein HMO1 has two DNA binding domains, box A and box B, and a lysine-rich C-terminal extension. Among other functions, HMO1 has been implicated as a component of the RNA polymerase I transcription m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88030525347a10abb337ac28771cc04
https://doi.org/10.1021/bi1003603
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Plný text Recenzováno Digitální knihovna AV ČR
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