Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Alan L. Mackay"'
Autor:
Jill Bayliss, Carl Koschmann, Chris Jones, Mariarita Santi, Nada Jabado, Daniel R. Wahl, Pooja Panwalkar, Anand Shankar, Viveka Nand Yadav, Siva Kumar Natarajan, Alexander R. Judkins, Arul M. Chinnaiyan, Amer Ghali, Selin Jessa, Tingting Qin, Stefan Sweha, Chan Chung, Marcin Cieslik, Drew Pratt, Kari Wilder-Romans, Visweswaran Ravikumar, Daniel Martinez, Suzanne J. Baker, Sriram Venneti, Timothy N. Phoenix, Andrew J. Scott, Matthew Pun, Alan L. Mackay, Arvind Rao, Claudia L. Kleinman
Publikováno v:
Sci Transl Med
High-grade gliomas with arginine or valine substitutions of the histone H3.3 glycine-34 residue (H3.3G34R/V) carry a dismal prognosis, and current treatments, including radiotherapy and chemotherapy, are not curative. Because H3.3G34R/V mutations rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce170f079bf2d1eeddb14377ddbe357
https://pubmed.ncbi.nlm.nih.gov/34644147
https://pubmed.ncbi.nlm.nih.gov/34644147
Autor:
Sameer Agnihotri, Joshua M. Dempster, Li Jiang, Erik Sundstroem, Johannes Gojo, Olivia A Hack, Christine Haberler, Kristina A. Cole, Miri Danan-Gotthold, McKenzie Shaw, Ed S. Lein, Yura Grabovska, Gustavo Alencastro Veiga Cruzeiro, Samantha E Hoffman, Ilon Liu, Christian Dorfer, Sanda Alexandrescu, Sara Temelso, Bernhard Englinger, Valeria Molinari, Christopher Rota, Lynn Bjerke, Chris Jones, Sten Linnarsson, René Geyeregger, Lisa Mayr, Irene Slavc, Cristina Bleil, Hafsa M Mire, Angela Waanders, Tara Barron, Angela Mastronuzzi, Gerda Ricken, Eshini Panditharatna, Kimberly Siletti, Lijuan Hu, Alan L. Mackay, Simon R. Stapleton, Michelle Monje, Emelie Braun, Michael Quezada, Mariella G. Filbin, David D Eisenstat, Sibylle Madlener, Maria Vinci, Rebecca Hodge, Fernando Carceller, Angel M. Carcaboso, Darren Hargrave, Rebecca Rogers
Publikováno v:
Neuro-Oncology
High-grade gliomas harboring H3 G34R/V mutations exclusively occur in the cerebral hemispheres of adolescents and young adults, suggesting a distinct neurodevelopmental origin. Combining multimodal bulk and single-cell genomics with unbiased genome-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551e267607ee523125c91b043551e069
http://europepmc.org/articles/PMC8168148
http://europepmc.org/articles/PMC8168148
Autor:
Alan L. Mackay
Publikováno v:
Glass Physics and Chemistry. 43:499-511
“The means by which enlightened rulers and sagacious generals moved and conquered others, that their achievements surpassed the masses, was advance knowledge. Advance knowledge cannot be gained from ghosts and spirits, inferred from phenomena, or p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75d81961e5e2813250fca112dc442a89
https://doi.org/10.1134/s108765961801008x
https://doi.org/10.1134/s108765961801008x
Autor:
Alan L. Mackay
Publikováno v:
Glass Physics and Chemistry. 43:489-498
Now, 25 years or so after the quasi-crystal affair, we can perhaps see the development of crystallography, as it turns into nanotechnology and molecular biology, in a still longer-term perspective as part of the struggle to understand the universe ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee58ebfc2357b51340de8425367897f4
https://doi.org/10.1134/s1087659617060074
https://doi.org/10.1134/s1087659617060074
Autor:
Maria Luisa Garrè, Adam C. Resnick, Felice Giangaspero, David R. Jones, Torsten Pietsch, Daniel Rodriguez, Christine Haberler, Meghna Das Thakur, David Capper, Helen Smith, Jacques Grill, Maura Massimino, Stefan M. Pfister, Valeria Molinari, Rachel Tam, Tim Jaspan, Angela J. Waanders, Juriaan Brouwer-Visser, Elisa Izquierdo, Pascale Varlet, Thomas Wurdinger, Anna Burford, Thomas S. Jacques, Giles Vassal, Paul S. Morgan, Pichai Raman, Chris Jones, Alan L. Mackay, Dominique Figarella-Branger, Josep Garcia
The HERBY trial was a phase-II open-label, randomised, multicentre trial evaluating bevacizumab in addition to temozolomide/radiotherapy in patients with newly-diagnosed non-brainstem high-grade glioma between the ages of 3-18 years. We collected spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35aa0ef8dbefb9b5a73c135f35860274
https://europepmc.org/articles/PMC6011917/
https://europepmc.org/articles/PMC6011917/
Autor:
Dominique D. Cooper, Elizabeth Y. Qin, Hannes Vogel, Michelle Monje, James Lennon, Surya Nagaraja, Chris Jones, Peter K. Jackson, Keene L. Abbott, Alan L. Mackay
Publikováno v:
SSRN Electronic Journal.
The lateral ventricle subventricular zone (SVZ) is a frequent and consequential site of pediatric and adult glioma spread, but the cellular and molecular mechanisms mediating this are poorly understood. We demonstrate that neural precursor cell (NPC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85fa772d9bdbbc9e989ada1376ae2951
https://doi.org/10.2139/ssrn.3155610
https://doi.org/10.2139/ssrn.3155610
Autor:
Florence Haudin, Geoffrey J. T. Cooper, Jerzy Maselko, Jason J. Pagano, Ivria J. Doloboff, Julyan H. E. Cartwright, David E. H. Jones, C. Ignacio Sainz-Díaz, Laura M. Barge, Alan L. Mackay, James T. Pantaleone, Silvana S. S. Cardoso, David Stone, Noreen L. Thomas, Yoshifumi Tanimoto, Michael J. Russell, Oliver Steinbock, Bruno Escribano, Leroy Cronin, Raymond E. Goldstein, Anne De Wit
Publikováno v:
BIRD: BCAM's Institutional Repository Data
instname
instname
Chemical gardens in laboratory chemistries ranging from silicates to polyoxometalates, in applications ranging from corrosion products to the hydration of Portland cement, and in natural settings ranging from hydrothermal vents in the ocean depths to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8e9a0b976aef00d75b502350fbc144
https://doi.org/10.1021/acs.chemrev.5b00014
https://doi.org/10.1021/acs.chemrev.5b00014
Autor:
Eva W. Stratford, Sebastian Brandner, Ana Paula Leite, Joanne Betts, David Michod, David Dinsdale, Paolo Salomoni, Matthew Ellis, A Deli, Stefano Bartesaghi, Angela Richard-Londt, Chris Jones, Rozita Roshani, Mikaella Vouri, Alan L. Mackay, Ningning Li, Sarah Oberndorfer, Valeria Amodeo, Aikaterini Lampada, Sara Galavotti, Ying Zhang, Pierluigi Nicotera, David Grimwade
Publikováno v:
Amodeo, V, A, D, Betts, J, Bartesaghi, S, Zhang, Y, Richard-Londt, A, Ellis, M, Roshani, R, Vouri, M, Galavotti, S, Oberndorfer, S, Leite, A P, Mackay, A, Lampada, A, Wessel Stratford, E, Li, N, Dinsdale, D, Grimwade, D, Jones, C, Nicotera, P, Michod, D, Brandner, S & Salomoni, P 2017, ' A PML/Slit Axis Controls Physiological Cell Migration and Cancer Invasion in the CNS ', Cell Reports, vol. 20, no. 2, pp. 411-426 . https://doi.org/10.1016/j.celrep.2017.06.047
Cell reports 20(2), 411-426 (2017). doi:10.1016/j.celrep.2017.06.047
Cell Reports, Vol 20, Iss 2, Pp 411-426 (2017)
Cell reports 20(2), 411-426 (2017). doi:10.1016/j.celrep.2017.06.047
Cell Reports, Vol 20, Iss 2, Pp 411-426 (2017)
Cell migration through the brain parenchyma underpins neurogenesis and glioblastoma (GBM) development. Since GBM cells and neuroblasts use the same migratory routes, mechanisms underlying migration during neurogenesis and brain cancer pathogenesis ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b72d1a59ba8ae3392adb2d1e22d1c28
https://eprints.soton.ac.uk/427469/
https://eprints.soton.ac.uk/427469/
Autor:
Henry Mandeville, Francesca Del Bufalo, Angel M. Carcaboso, Sucheta Vaidya, Mariona Suñol, Matthew Clarke, Elisa Izquierdo, Andrew J. Martin, Lynley V. Marshall, Safa Al-Sarraj, Simon P. Robinson, Anna Burford, Christopher J. Lord, Chris Jones, Ketty Kessler, Samatha Hettige, Simon R. Stapleton, Jaume Mora, Jessica K.R. Boult, Kathryn R. Taylor, Andrew S. Moore, Rebecca Rogers, Ofelia Cruz, Jane Pears, Leslie R. Bridges, Valeria Molinari, Mariama Fofana, Carmen Torres, Bassel Zebian, Sara Temelso, Christopher Chandler, Angela Mastronuzzi, Lynn Bjerke, Diana Carvalho, Alan L. Mackay, Helen Pemberton, Maria Vinci, Janat Fazal Salom, Fernando Carceller, Andrea Carai
Publikováno v:
Neuro-Oncology. 20:i93-i94
Paediatric high grade glioma and diffuse midline glioma (including DIPG) are comprised of multiple biological and clinical subgroups, the majority of which urgently require novel therapies. Patient-derived in vitro primary cell cultures represent pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87455bc96712b8c9c75f213463dc723
https://doi.org/10.1093/neuonc/noy059.295
https://doi.org/10.1093/neuonc/noy059.295