Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Alan L. Hutchison"'
Autor:
Fangke Xu, Elzbieta Kula-Eversole, Marta Iwanaszko, Alan L. Hutchison, Aaron Dinner, Ravi Allada
Publikováno v:
Cell Reports, Vol 27, Iss 1, Pp 59-70.e4 (2019)
Summary: Neurodegenerative diseases commonly involve the disruption of circadian rhythms. Studies indicate that mutant Huntingtin (mHtt), the cause of Huntington’s disease (HD), disrupts circadian rhythms often before motor symptoms are evident. Ye
Externí odkaz:
https://doaj.org/article/32158e3723d44796b12f4653fb0b32e2
Autor:
Sean M. Gibbons, Monika Scholz, Alan L. Hutchison, Aaron R. Dinner, Jack A. Gilbert, Maureen L. Coleman
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT Diversity is often associated with the functional stability of ecological communities from microbes to macroorganisms. Understanding how diversity responds to environmental perturbations and the consequences of this relationship for ecosyste
Externí odkaz:
https://doaj.org/article/ed23b15a13fd48a1adada4a261743dfb
Autor:
Matthew A. Odenwald, Huaiying Lin, Christopher Lehmann, Nicholas P. Dylla, Ramanujam Ramanswamy, Angelica Moran, Alan L. Hutchison, Matthew R. Stutz, Mark Dela Cruz, Emerald Adler, Jaye Boissiere, Maryam Khalid, Jackelyn Cantoral, Fidel Haro, Rita A. Oliveira, Emily Waligurski, Thomas G. Cotter, Samuel H. Light, Kathleen G. Beavis, Anitha Sundararajan, Ashley M. Sidebottom, K. Gautham Reddy, Sonali Paul, Anjana Pilliai, Helen S. Te, Mary E. Rinella, Michael R. Charlton, Eric G. Pamer, Andrew I. Aronsohn
Progression of chronic liver diseases is precipitated by hepatocyte loss, inflammation and fibrosis. This process results in the loss of critical hepatic functions, increasing morbidity and the risk of infection. Medical interventions that treat comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::698143e316e1123dad648abbd00a9325
https://doi.org/10.1101/2023.02.14.23285927
https://doi.org/10.1101/2023.02.14.23285927
Publikováno v:
Clin Liver Dis (Hoboken)
Content available: Author Interview and Audio Recording.
Autor:
Dae-Sung Hwangbo, Yong-Jae Kwon, Marta Iwanaszko, Peng Jiang, Ladan Abbasi, Nicholas Wright, Sarayu Alli, Alan L. Hutchison, Aaron R. Dinner, Rosemary I Braun, Ravi Allada
Circadian clocks may mediate lifespan extension by caloric or dietary restriction (DR). We find that the core clock transcription factorClockis crucial for a robust longevity and fecundity response to DR inDrosophila. To identify clock-controlled med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::300c00a3d8a79a2f935d57949c3a66f0
https://doi.org/10.1101/2023.01.04.522718
https://doi.org/10.1101/2023.01.04.522718
Autor:
Alan L. Hutchison, Anjana Pillai
Publikováno v:
Current Opinion in Organ Transplantation. 26:339-345
Purpose of review To assess the impact of coronavirus disease 2019 (COVID-19) and the pandemic on liver transplant candidates, recipients, and donors, and review guidelines and recommendations for integrating COVID-19 therapies into current practice.
Publikováno v:
The Journal of Hand Surgery (Asian-Pacific Volume). 22:88-92
Background: This controlled randomized experiment tested the research hypothesis that providing the CTS-6 quantitative diagnostic information to hand surgeons affects the diagnosis of carpal tunnel syndrome.Methods: Surgeon members of American Associ
Autor:
Roger D. Hurst, Aaron R. Dinner, Nitya Talasila, Zifeng Deng, Alessandro Fichera, Joel Pekow, Alan L. Hutchison, Konstantin Umanskiy, Marc Bissonnette, John Hart, Kymberly Harrington, Stephen B. Hanauer, Katherine Meckel, David T. Rubin
Publikováno v:
Inflammatory bowel diseases. 23(8)
BACKGROUND As mechanisms of neoplasia in patients with ulcerative colitis (UC) remain poorly understood, we sought to identify pathways of carcinogenesis in this high-risk population. METHODS MicroRNA (miRNA) and mRNA expression was examined in nondy
MotivationThere is much interest in using genome-wide expression time series to identify circadian genes. However, the cost and effort of such measurements often limits data collection. Consequently, it is difficult to assess the experimental uncerta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb93f2e5f3cc6eb3856001d787799115
https://doi.org/10.1101/118521
https://doi.org/10.1101/118521
Autor:
Aaron R. Dinner, Alan L. Hutchison
There is much interest in using genome-wide expression time series to identify circadian genes. Several methods have been developed to test for rhythmicity in sparsely sampled time series typical of such measurements. Because these methods are statis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a34e0454ea67936debd97edced7d92