Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Alan L. Epstein"'
Autor:
Alessandro Salatino, Maria Mirabelli, Eusebio Chiefari, Marta Greco, Anna Di Vito, Giuseppe Bonapace, Francesco S. Brunetti, Fabio Crocerossa, Alan L. Epstein, Daniela P. Foti, Antonio Brunetti
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
IntroductionGerm cell tumors (GCTs) are the most common type of cancer in young men. These tumors usually originate from the testis, but they can occasionally develop from extragonadal sites probably due to primordial germ cells (PGCs) migration erro
Externí odkaz:
https://doaj.org/article/3fe3f0c17d2c44539d3ca1af94c242c4
Autor:
Naomi S. Sta Maria, Leslie A. Khawli, Vyshnavi Pachipulusu, Sharon W. Lin, Long Zheng, Daniel Cohrs, Xiaodan Liu, Peisheng Hu, Alan L. Epstein, Russell E. Jacobs
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Quantitative in vivo monitoring of cell biodistribution offers assessment of treatment efficacy in real-time and can provide guidance for further optimization of chimeric antigen receptor (CAR) modified cell therapy. We evaluated the utility
Externí odkaz:
https://doaj.org/article/1a42eddcd18d4b17b25c6a34627d8118
Autor:
Shigang Xiong, Paulette Mhawech-Fauceglia, Denice Tsao-Wei, Lynda Roman, Rajesh K. Gaur, Alan L. Epstein, Jacek Pinski
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract We investigated the association of LHR expression in epithelial ovarian cancer (OC) with clinical and pathologic characteristics of patients. LHR expression was examined immunohistochemically using tissue microarrays (TMAs) of specimens from
Externí odkaz:
https://doaj.org/article/dfae97a8ecec4712854ee0ba764ff0a8
Autor:
Lauriane Galle-Treger, Ishwarya Sankaranarayanan, Benjamin P. Hurrell, Emily Howard, Richard Lo, Hadi Maazi, Gavin Lewis, Homayon Banie, Alan L. Epstein, Peisheng Hu, Virender K. Rehan, Frank D. Gilliland, Hooman Allayee, Pejman Soroosh, Arlene H. Sharpe, Omid Akbari
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Type-2 innate lymphoid cells (ILC2s) are an immune population secreting Th2 cytokines playing a role in the regulation of adipose metabolic homeostasis. Here the authors show that engagement of GITR, a member of the TNF superfamily, in activated ILC2
Externí odkaz:
https://doaj.org/article/1c23f79b445447f9ae0cd84879992375
Autor:
Weijun Wang, Haiping He, Shan Zeng, Hee-Yeon Cho, Radu O. Minea, Steven D. Swenson, Long Zheng, Alan L. Epstein, Apostolos Stathopoulos, Ligang Chen, Axel H. Schönthal, Thomas C. Chen
Publikováno v:
Journal of Neurosurgery. :1-9
OBJECTIVE Immune checkpoint-inhibitory therapeutic antibodies have shown striking activity against several types of cancers but are less effective against brain-localized malignancies, in part due to the protective effect of the blood-brain barrier (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ad7d55c548a65370db71df8a177a49c
https://doi.org/10.3171/2022.12.jns221285
https://doi.org/10.3171/2022.12.jns221285
Autor:
Soheila Shirinbak, Randall Y. Chan, Shilpa Shahani, Sakunthala Muthugounder, Rebekah Kennedy, Long T. Hung, G. Esteban Fernandez, Michael D. Hadjidaniel, Babak Moghimi, Michael A. Sheard, Alan L. Epstein, Muller Fabbri, Hiroyuki Shimada, Shahab Asgharzadeh
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Immune checkpoint therapy has resulted in minimal clinical response in many pediatric cancers. We sought to understand the influence of immune checkpoint inhibition using anti-PD-1 and anti-CTLA-4 antibodies individually, in combination, and after ch
Externí odkaz:
https://doaj.org/article/0915f141d7a649279983360de71ca579
Autor:
Naoki Oishi, Tanya Hundal, Jessica L. Phillips, Surendra Dasari, Guangzhen Hu, David S. Viswanatha, Rong He, Ming Mai, Hailey K. Jacobs, Nada H. Ahmed, Sergei I. Syrbu, Youssef Salama, Jennifer R. Chapman, Francisco Vega, Jagmohan Sidhu, N. Nora Bennani, Alan L. Epstein, L. Jeffrey Medeiros, Mark W. Clemens, Roberto N. Miranda, Andrew L. Feldman
Publikováno v:
Haematologica, Vol 106, Iss 6 (2020)
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a recently characterized T-cell malignancy that has raised significant patient safety concerns and led to worldwide impact on the implants used and clinical management of patients
Externí odkaz:
https://doaj.org/article/b160bd80598140648c1c52e59ac73758
Autor:
Samuel Y. Ng, Noriaki Yoshida, Amanda L. Christie, Mahmoud Ghandi, Neekesh V. Dharia, Joshua Dempster, Mark Murakami, Kay Shigemori, Sara N. Morrow, Alexandria Van Scoyk, Nicolas A. Cordero, Kristen E. Stevenson, Maneka Puligandla, Brian Haas, Christopher Lo, Robin Meyers, Galen Gao, Andrew Cherniack, Abner Louissaint, Valentina Nardi, Aaron R. Thorner, Henry Long, Xintao Qiu, Elizabeth A. Morgan, David M. Dorfman, Danilo Fiore, Julie Jang, Alan L. Epstein, Ahmet Dogan, Yanming Zhang, Steven M. Horwitz, Eric D. Jacobsen, Solimar Santiago, Jian-Guo Ren, Vincent Guerlavais, D. Allen Annis, Manuel Aivado, Mansoor N. Saleh, Amitkumar Mehta, Aviad Tsherniak, David Root, Francisca Vazquez, William C. Hahn, Giorgio Inghirami, Jon C. Aster, David M. Weinstock, Raphael Koch
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
T- and NK-cell lymphomas (TCL) are a group of lymphoid malignancies characterized by poor prognosis, but the absence of appropriate pre-clinical models has hampered the development of effective therapies. Here the authors establish several pre-clinic
Externí odkaz:
https://doaj.org/article/ecc83cf960564bd2938fc055d45d8a01
Autor:
Khaled Alharshawi, Alejandra Marinelarena, Prabhakaran Kumar, Osama El-Sayed, Palash Bhattacharya, Zuoming Sun, Alan L. Epstein, Ajay V. Maker, Bellur S. Prabhakar
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract We have previously shown that OX40L/OX40 interaction is critical for TCR-independent selective proliferation of Foxp3+ Tregs, but not Foxp3− effector T-cells (Teff), when CD4+ T-cells are co-cultured with GM-CSF derived bone marrow dendrit
Externí odkaz:
https://doaj.org/article/57f641e5cbe94b2d983028a3edbd7fd1
Autor:
Stan G. Louie, Alan L. Epstein, Nicos A. Petasis, Mark Humayun, Zeyang Li, Andrew Mead, Tracey Lin, Hua Pei, Malika Salimova, Isaac Asante, Eugene Zhou, Kabir Ahluwalia, Brandon Ebright, EunJeong Yoo, Priyal Dave, Tiange Dong
Figure S1 shows the gating strategy for PMN apoptosis analysis, RT-PCR, immunofluorescence staining, and flow cytometry analyses of FPR2/ALX-transfected HEK cells, effect of NAP1051 on dTHP-1 cells with selective kinase inhibitors, and Western blot w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af3028e768d3304d9398968c526f175
https://doi.org/10.1158/1535-7163.22522777.v1
https://doi.org/10.1158/1535-7163.22522777.v1
