Výsledky vyhledávání - "Alan Koterba"

Subcutaneous Immunoglobulin 16.5% (Cutaquig®) in Primary Immunodeficiency Disease: Safety, Tolerability, Efficacy, and Patient Experience with Enhanced Infusion Regimens

Autor: Sudhir Gupta, James DeAngelo, Isaac Melamed, Jolan E. Walter, Ai-Lan Kobayashi, Tracy Bridges, J. Wesley Sublett, Jonathan A. Bernstein, Alan Koterba, Michael Manning, Joanna Maltese, Sonja Hoeller, Eva Turpel-Kantor, Huub Kreuwel, Roger H. Kobayashi

Publikováno v: Journal of Clinical Immunology.

Purpose To achieve reductions in infusion time, infusion sites, and frequency, a prospective, open-label, multicenter, Phase 3 study evaluated the safety, efficacy, and tolerability of subcutaneous immunoglobulin (SCIG) 16.5% (Cutaquig®, Octapharma)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e032fde4f9e7c9f51febd51147c3e6d1
https://doi.org/10.1007/s10875-023-01509-4

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Initiation of immunoglobulin therapy by subcutaneous administration in immunodeficiency patients naive to replacement therapy

Autor: Alan Koterba, Mark R. Stein

Publikováno v: Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology

Background Patients with immunodeficiency diseases require lifelong treatment with immunoglobulin (Ig), yet few studies have vetted dosing strategies and effectiveness of Ig in older patient populations. Patients requiring subcutaneous (SC) Ig (SCIG)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693ea7e5a712ee6ce6d9823fe927243a
http://europepmc.org/articles/PMC4273447

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Aberrant Regulation of Transforming Growth Factor-α during the Establishment of Growth Arrest and Quiescence of Growth Factor Independent Cells

Autor: Joan M. Carboni, Rana A. Awwad, Wenhui Li, Lisa E. Humphrey, Degeng Wang, Basker Periyasamy, Junhua Yang, James K V Willson, Michael G. Brattain, Alan Koterba, Kevin G. Coleman, Mark Lynch, Barry L. Ziober, Gillian M. Howell

Publikováno v: Journal of Biological Chemistry. 273:9214-9223

Autocrine transforming growth factor alpha (TGFalpha) is an important positive growth effector in malignant cells and plays a significant role in generating the growth factor-independent phenotype associated with malignant progression. However, the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea427fb4427f3393b54ec4b519cd2485
https://doi.org/10.1074/jbc.273.15.9214

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Regulation of Transforming Growth Factor α Expression in a Growth Factor-Independent Cell Line

Autor: Lisa E. Humphrey, Rana A. Awwad, Barry L. Ziober, Joan M. Carboni, Basker Periyasamy, Wenhui Li, Michael G. Brattain, Mark Lynch, Alan Koterba, Kevin G. Coleman, Gillian M. Howell, James K V Willson

Publikováno v: Molecular and Cellular Biology. 18:303-313

Aberrant transcriptional regulation of transforming growth factor alpha (TGF alpha) appears to be an important contributor to the malignant phenotype and the growth factor independence with which malignancy is frequently associated. However, little i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700ecddee75292e303d0be1060b66f4e
https://doi.org/10.1128/mcb.18.1.303

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Safety and efficacy of home-based subcutaneous immunoglobulin G in elderly patients with primary immunodeficiency diseases

Autor: Melvin Berger, Mark R. Stein, Alan Koterba, Linda Rodden

Publikováno v: Postgraduate medicine. 123(5)

Subcutaneous immunoglobulin (SCIG) is as effective as intravenous immunoglobulin (IVIG) in minimizing infections in patients with primary immunodeficiency diseases (PIDD) and is associated with fewer systemic adverse events (AEs). Self-infusion/home-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e68d0f9430cafa853e74aebc1be8110
https://pubmed.ncbi.nlm.nih.gov/23391683

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