Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alan Koncarevic"'
Autor:
Alan Koncarevic, Ravindra Kumar, Katia Liharska, Jasbir Seehra, Jeffrey A. Ucran, Shingo Kajimura, Milton Cornwall-Brady, Abigail Pullen, Elizabeth Howard, Bruce M. Spiegelman, Amy Andreucci, Sako Dianne S, Jennifer Lachey, Asya Grinberg
Publikováno v:
Endocrinology. 153(7)
Obesity results from disproportionately high energy intake relative to energy expenditure. Many therapeutic strategies have focused on the intake side of the equation, including pharmaceutical targeting of appetite and digestion. An alternative appro
Autor:
Jasbir Seehra, Ben Umiker, Joseph Barberio, Kathryn W. Underwood, Jeffrey A. Ucran, Alan Koncarevic, June Liu, Katia Liharska, Matthew S. Spaits, Jennifer Lachey, Monique V. Davies, Scott Pearsall, Kathleen N. Tomkinson, Ravindra Kumar, Theresa Baker, Abigail Pullen, Travis E. Monnell, Elizabeth Howard, Sako Dianne S, Milton Cornwall-Brady, Asya Grinberg
Publikováno v:
Endocrinology. 151(9)
Androgen deprivation, a consequence of hypogonadism, certain cancer treatments, or normal aging in men, leads to loss of muscle mass, increased adiposity, and osteoporosis. In the present study, using a soluble chimeric form of activin receptor type
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 21(2)
Ubiquitination-dependent proteolysis is a fundamental process underlying skeletal muscle atrophy. Thus, the role of ubiquitin ligases is of great interest. There are no focused studies in muscle on the ubiquitin ligase Nedd4. We first confirmed incre
Autor:
Andrew R, Judge, Alan, Koncarevic, R Bridge, Hunter, Hsiou-Chi, Liou, Robert W, Jackman, Susan C, Kandarian
Publikováno v:
American journal of physiology. Cell physiology. 292(1)
Skeletal muscle atrophy is associated with a marked and sustained activation of nuclear factor-kappaB (NF-kappaB) activity. Previous work showed that p50 is one of the NF-kappaB family members required for this activation and for muscle atrophy. In t
Autor:
Jascha D. Parkington, Eric J. Stevenson, Roger A. Fielding, Joachim Theilhaber, Paul G. Giresi, Susan C. Kandarian, Alan Koncarevic
Publikováno v:
Physiological genomics. 21(2)
Investigating the molecular mechanisms underlying sarcopenia in humans with the use of microarrays has been complicated by low sample size and the variability inherent in human gene expression profiles. We have conducted a study using Affymetrix Gene
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 98(4)
Skeletal muscle wasting is a pervasive phenomenon that can result from a wide range of pathological conditions as well as from habitual muscular inactivity. The present work describes a cell-culture condition that induces significant atrophy in skele
Autor:
Heather Mitchell-Felton, Alan Koncarevic, R. Bridge Hunter, Susan C. Kandarian, David A. Essig, Eric J. Stevenson
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 16(6)
Although cytokine-induced nuclear factor kappaB (NF-kappaB) pathways are involved in muscle wasting subsequent to disease, their potential role in disuse muscle atrophy has not been characterized. Seven days of hind limb unloading led to a 10-fold ac