Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Alan Kadek"'
Autor:
Yuzhen Feng, Dominik van Bodegraven, Alan Kádek, Ignacio L. B. Munguira, Laura Soria-Martinez, Sarah Nentwich, Sreedeepa Saha, Florian Chardon, Daniel Kavan, Charlotte Uetrecht, Mario Schelhaas, Wouter H. Roos
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract High-risk human papillomaviruses (HPVs) cause various cancers. While type-specific prophylactic vaccines are available, additional anti-viral strategies are highly desirable. Initial HPV cell entry involves receptor-switching induced by stru
Externí odkaz:
https://doaj.org/article/ad05749e2602467997b382ccd9878f0a
Autor:
Shivam Shukla, Jan Komarek, Zora Novakova, Jana Nedvedova, Kseniya Ustinova, Pavla Vankova, Alan Kadek, Charlotte Uetrecht, Haydyn Mertens, Cyril Barinka
Publikováno v:
The FEBS journal 290(3), 821-836 (2022). doi:10.1111/febs.16616
The FEBS journal 290(3), 821 - 836 (2022). doi:10.1111/febs.16616
Human histone deacetylase 6 (HDAC6) is a structurally unique, multido-main protein implicated in a variety of physiological processes includingcytoskeletal remodelling and the mai
Human histone deacetylase 6 (HDAC6) is a structurally unique, multido-main protein implicated in a variety of physiological processes includingcytoskeletal remodelling and the mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d025c08504885036741e0dc51197cbd
https://pubmed.ncbi.nlm.nih.gov/36062318
https://pubmed.ncbi.nlm.nih.gov/36062318
Autor:
null Shivam Shukla, null Jan Komarek, null Zora Novakova, null Jana Nedvedova, null Kseniya Ustinova, null Pavla Vankova, null Alan Kadek, null Charlotte Uetrecht, null Haydyn Mertens, null Cyril Barinka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c1a86405805f75e56875c21b60a14c
https://doi.org/10.1111/febs.16616/v3/response1
https://doi.org/10.1111/febs.16616/v3/response1
Autor:
Anja Konietzny, Jasper Grendel, Alan Kadek, Michael Bucher, Yuhao Han, Nathalie Hertrich, Dick H W Dekkers, Jeroen A A Demmers, Kay Grünewald, Charlotte Uetrecht, Marina Mikhaylova
Publikováno v:
EMBO Journal, 41(4):e106523. Wiley-Blackwell
The EMBO journal 41(4), e106523 (2022). doi:10.15252/embj.2020106523
The EMBO journal 41(4), e106523 (2022). doi:10.15252/embj.2020106523
The EMBO journal 41(4), e106523 (2022). doi:10.15252/embj.2020106523
Excitatory synapses of principal hippocampal neurons are frequently located on dendritic spines. The dynamic strengthening or weakening of individual inputs results in structur
Excitatory synapses of principal hippocampal neurons are frequently located on dendritic spines. The dynamic strengthening or weakening of individual inputs results in structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5c43f02bfab770c23b37323e2a9eee
https://pubmed.ncbi.nlm.nih.gov/34935159
https://pubmed.ncbi.nlm.nih.gov/34935159
Autor:
Christoph Sygmund, Christophe V. F. P. Laurent, Petr Man, Stefan Scheiblbrandner, Christian Schuster, Daniel Kracher, Alan Kadek, Petr Halada, Frantisek Filandr, Alfons K. G. Felice, Roland Ludwig, Chris Oostenbrink, Franziska Schachinger, Lorenz Schwaiger
Publikováno v:
ACS Catalysis
The natural function of cellobiose dehydrogenase (CDH) to donate electrons from its catalytic flavodehydrogenase (DH) domain via its cytochrome (CYT) domain to lytic polysaccharide monooxygenase (LPMO) is an example of a highly efficient extracellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616c4b28f7145a4ebba473744fdeaabf
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611258
Protein hydrogen/deuterium exchange (HDX) coupled to mass spectrometry (MS) can be used to study interactions of proteins with various ligands, to describe the effects of mutations, or to reveal structural responses of proteins to different experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fec524999b22f5858a89e12579eac13
https://doi.org/10.1007/978-1-0716-1126-5_11
https://doi.org/10.1007/978-1-0716-1126-5_11
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2247
Protein hydrogen/deuterium exchange (HDX) coupled to mass spectrometry (MS) can be used to study interactions of proteins with various ligands, to describe the effects of mutations, or to reveal structural responses of proteins to different experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5bee0b6db4ea77e694381472c3090b19
https://pubmed.ncbi.nlm.nih.gov/33301119
https://pubmed.ncbi.nlm.nih.gov/33301119
Autor:
Martin Zickler, Berfin Schaumburg, Axel Nierhaus, Karin Klingel, Pietro Scaturro, Hanna Jania, Maria Schroeder, Dominik Jarczak, Stephanie Stanelle-Bertram, Alan Kadek, Vanessa Krump-Buzumkic, Georg Beythien, Wolfgang Baumgärtner, Nancy Mounogou Kouassi, Kathrin Becker, Gabriel Guelsah, Sebastian Beck, Vinicius Pinho dos Reis, Zacharias Müller, Charlotte Uetrecht, Stefan Kluge, Tian Bai
SARS-CoV-2 infection is associated with increased morbidities in men compared to women. Androgens are believed to play an important role in SARS-CoV-2 pathogenesis in men due to the postulated androgen-dependency of ACE2 and TMPRSS2. However, it is y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa66340d233c8e5e7f7a2b6671ea4277
https://doi.org/10.21203/rs.3.rs-107474/v1
https://doi.org/10.21203/rs.3.rs-107474/v1
Publikováno v:
Drug Discovery Today: Technologies
During the last years, X-ray free electron lasers (XFELs) have emerged as X-ray sources of unparalleled brightness, delivering extreme amounts of photons in femtosecond pulses. As such, they have opened up completely new possibilities in drug discove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870a31a12f2d69bf9243798d25765b06
https://pubmed.ncbi.nlm.nih.gov/34906329
https://pubmed.ncbi.nlm.nih.gov/34906329
Autor:
Kasper D. Rand, Patrick S. Merkle, Ingvar R. Möller, Marika Slivacka, Marek Polák, Růžena Lišková, Alan Kadek, Petr Man, Claus J. Loland, Anne Kathrine Nielsen, Eliska Pospisilova, Jiří Hausner
Publikováno v:
Analytical chemistry. 91(17)
Insight into the structure-function relationship of membrane proteins is important to understand basic cell function and inform drug development, as these are common targets for drugs. Hydrogen/deuterium exchange mass spectrometry (HDX-MS) is an esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6a341c1fbdaa79240870f7925b43f1
https://pubmed.ncbi.nlm.nih.gov/31408320
https://pubmed.ncbi.nlm.nih.gov/31408320