Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Alan K. Hatfield"'
Autor:
James R. Jett, James A. Mailliard, Michael D. Bauman, Roscoe F. Morton, Alan K. Hatfield, John W. Kugler, Ralph Levitt, Shauna Hillman, Randolph S. Marks
Publikováno v:
Cancer. 97:2498-2503
BACKGROUND The objective of this study was to test the response rate and toxicity of alternating chemotherapy in previously untreated patients with extensive-stage small cell lung carcinoma (SCLC). METHODS Patients with histologically proven, extensi
Autor:
G. H. Farr, J. A. Jefferies, Vera J. Suman, Loren K. Tschetter, Nancy E Fay, Roscoe F. Morton, Alan K. Hatfield, Thomas A. Gaffey, Lynn C. Hartmann, Bobbie S. Gostout, Samir Abu-Ghazaleh, Mary M. Gallenberg
Publikováno v:
International Journal of Gynecology & Obstetrics. 74:207-210
This paper presents a randomized clinical trial of standard local ablative treatment with and without systemic interferon-alpha for cervical dysplasia. To determine the extent of the lesion study participants underwent colposcopic examination and loc
Autor:
Steven A. Kuross, John T. Cole, Terrence L. Cascino, James A. Mailliard, Roscoe F. Morton, Judith R. O'Fallon, William L. McGinnis, Preston D. Steen, Alan K. Hatfield, Jan C. Buckner, Paula J. Schomberg, Bernd W. Scheithauer, Albert M. Bernath
Publikováno v:
Cancer. 92:420-433
BACKGROUND The current study was conducted to determine whether the addition of interferon-α (IFN-α) to treatment with radiation therapy and carmustine (BCNU) improves time to disease progression or overall survival in patients with high-grade glio
Autor:
Richard M. Goldberg, John Kugler, Alan K. Hatfield, James A. Knost, James E. Krook, Michelle R. Mahoney, Daniel J. Sargent, Henry C. Pitot
Publikováno v:
Cancer. 89:1699-1705
BACKGROUND Topoisomerase I inhibitors have demonstrated clinical activity in patients with metastatic colorectal carcinoma. The authors performed a Phase II study to evaluate the objective tumor response rate of 2 different doses and schedules of 9-a
Autor:
Philip J. Stella, James E. Krook, James A. Mailliard, Lynn C. Hartmann, Tom R. Fitch, Edith A. Perez, James N. Ingle, Carl G. Kardinal, Suresh Nair, David W. Hillman, Alan K. Hatfield
Publikováno v:
Cancer. 88:124-131
BACKGROUND This Phase II multicenter study evaluated the efficacy and toxicity of paclitaxel (200 mg/m2 by 3-hour infusion) with carboplatin (area under the curve 6 mg/mL per minute) administered every 3 weeks as first-line therapy for women with met
Autor:
Bernd W. Scheithauer, S. Vincent Rajkumar, Joel M. Reid, Paul J. Novotny, P. Steven Johnson, Suresh G. Nair Md, Matthew M. Ames, James E. Krook, Roscoe F. Morton, Jan C. Buckner, Stephanie L. Safgren, Alan K. Hatfield
Publikováno v:
Journal of Neuro-Oncology. 49:255-261
We conducted a randomized phase II study to determine the efficacy of dacarbazine (DTIC) in recurrent gliomas. Patients were randomly assigned to receive either DTIC 750 mg/m2 IV day 1 every 28 days (Arm A) or DTIC 200 mg/m2 IV days 1–5 every 28 da
Autor:
Terrence L. Cascino, Jeff A. Sloan, John W. Kugler, Roy Molina, Kendrith M. Rowland, Harbhajan Dhaliwal, Charles L. Loprinzi, Donald B. Wender, Chirantan Ghosh, Neil M. Ellison, Allen M. Vukov, Alan K. Hatfield, Angela W. Miser
Publikováno v:
Journal of Clinical Oncology. 15:2974-2980
PURPOSE A minority of cancer survivors develops long-term postsurgical neuropathic pain. Based on evidence that capsaicin, the pungent ingredient in hot chili peppers, might be useful for treating neuropathic pain, we developed the present clinical t
Autor:
Alan K. Hatfield, Vera J. Suman, James B. Gerstner, Lynn C. Hartmann, Patricia A. Johnson, Charles L. Loprinzi, Dean H. Gesme, John K. Camoriano, James N. Ingle, James A. Mailliard
Publikováno v:
Cancer. 80:218-224
BACKGROUND It is common practice to utilize a series of different hormonal agents in the treatment of postmenopausal women who, despite disease progression, continue to be candidates for hormonal therapy on a clinical basis. Letrozole is a new highly
Autor:
Charles L. Loprinzi, Claudia Johnson, Robert A. Nelimark, John C. Michalak, Joseph E. Oesterling, Tammy Fischer, Walter W. Bate, Judith R. O'Fallon, Susan K. Quella, Raylene M. Rospond, Alan K. Hatfield, Ann Marie Dose, Nancy E. Klatt
Publikováno v:
New England Journal of Medicine. 331:347-352
Vasomotor hot flashes are a common symptom in women during menopause and in men who have undergone androgen-deprivation therapy for prostate cancer. Although treatment with estrogens in women and androgens in men can attenuate these symptoms, these h
Autor:
Lynn C. Hartmann, Michael H. Veeder, James A. Mailliard, James E. Krook, Sin-Ho Jung, James N. Ingle, Alan K. Hatfield, Dean H. Gesme, Richard M. Goldberg, John F. Foley
Publikováno v:
Cancer. 73:2337-2343
Background. The fraction of breast cancer cells undergoing DNA synthesis at any one time is relatively low, which is problematic because most chemotherapeutic agents are most effective against dividing cells. Estrogens administered in vitro and in vi