Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Alan K Jarmusch"'
Autor:
Tim Ken Mackey, Alan K Jarmusch, Qing Xu, Kunyang Sun, Aileen Lu, Shaden Aguirre, Jessica Lim, Simran Bhakta, Pieter C Dorrestein
Publikováno v:
JMIR Public Health and Surveillance, Vol 8, Iss 12, p e41834 (2022)
BackgroundAntimicrobial resistance is a significant global public health threat. However, the impact of sourcing potentially substandard and falsified antibiotics via the internet remains understudied, particularly in the context of access to and qua
Externí odkaz:
https://doaj.org/article/fab7ec3a098c4267be3d4199d8024e30
Autor:
Alan K Jarmusch, Clint M Alfaro, Valentina Pirro, Eyas M Hattab, Aaron A Cohen-Gadol, R Graham Cooks
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163180 (2016)
Desorption electrospray ionization-mass spectrometry (DESI-MS) imaging was used to analyze unmodified human brain tissue sections from 39 subjects sequentially in the positive and negative ionization modes. Acquisition of both MS polarities allowed m
Externí odkaz:
https://doaj.org/article/aae3f2cfae8f45e6a011dddd34e620fe
Autor:
Robin Schmid, Daniel Petras, Louis-Félix Nothias, Mingxun Wang, Allegra T. Aron, Annika Jagels, Hiroshi Tsugawa, Johannes Rainer, Mar Garcia-Aloy, Kai Dührkop, Ansgar Korf, Tomáš Pluskal, Zdeněk Kameník, Alan K. Jarmusch, Andrés Mauricio Caraballo-Rodríguez, Kelly C. Weldon, Melissa Nothias-Esposito, Alexander A. Aksenov, Anelize Bauermeister, Andrea Albarracin Orio, Carlismari O. Grundmann, Fernando Vargas, Irina Koester, Julia M. Gauglitz, Emily C. Gentry, Yannick Hövelmann, Svetlana A. Kalinina, Matthew A. Pendergraft, Morgan Panitchpakdi, Richard Tehan, Audrey Le Gouellec, Gajender Aleti, Helena Mannochio Russo, Birgit Arndt, Florian Hübner, Heiko Hayen, Hui Zhi, Manuela Raffatellu, Kimberly A. Prather, Lihini I. Aluwihare, Sebastian Böcker, Kerry L. McPhail, Hans-Ulrich Humpf, Uwe Karst, Pieter C. Dorrestein
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Abstract Molecular networking connects mass spectra of molecules based on the similarity of their fragmentation patterns. However, during ionization, molecules commonly form multiple ion species with different fragmentation behavior. As a result, the
Externí odkaz:
https://doaj.org/article/c79c811ddd0b40428c0ef8e4c5a7fe4c
Autor:
Roxana Coras, Cameron Martino, Julia M. Gauglitz, Francesca Cedola, Anupriya Tripathi, Alan K. Jarmusch, Maram Alharthi, Marta Fernandez‐Bustamante, Meritxell Agustin‐Perez, Abha Singh, Soo‐In Choi, Tania Rivera, Katherine Nguyen, Tatyana Shekhtman, Tiffany Holt, Susan Lee, Shahrokh Golshan, Pieter C. Dorrestein, Rob Knight, Monica Guma
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 7, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/060d7b5c223449169399b643b94f466f
Autor:
Andre Mu, Daniel McDonald, Alan K. Jarmusch, Cameron Martino, Caitriona Brennan, Mackenzie Bryant, Gregory C. Humphrey, Julia Toronczak, Tara Schwartz, Dominic Nguyen, Gail Ackermann, Anthony D’Onofrio, Steffanie A. Strathdee, Robert T. Schooley, Pieter C. Dorrestein, Rob Knight, Saima Aslam
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-8 (2021)
Abstract Background Infectious bacterial diseases exhibiting increasing resistance to antibiotics are a serious global health issue. Bacteriophage therapy is an anti-microbial alternative to treat patients with serious bacterial infections. However,
Externí odkaz:
https://doaj.org/article/427b76349aaa475d98112b027db52245
Autor:
Morgan Panitchpakdi, Kelly C. Weldon, Alan K. Jarmusch, Emily C. Gentry, Arianna Choi, Yadira Sepulveda, Shaden Aguirre, Kunyang Sun, Jeremiah D. Momper, Pieter C. Dorrestein, Shirley M. Tsunoda
Publikováno v:
PLoS ONE, Vol 17, Iss 7 (2022)
Clinical testing typically relies on invasive blood draws and biopsies. Alternative methods of sample collection are continually being developed to improve patient experience; swabbing the skin is one of the least invasive sampling methods possible.
Externí odkaz:
https://doaj.org/article/d127b390ce8e45eb868dec29462c4c88
Autor:
Alison Vrbanac, Kathryn A. Patras, Alan K. Jarmusch, Robert H. Mills, Samuel R. Shing, Robert A. Quinn, Fernando Vargas, David J. Gonzalez, Pieter C. Dorrestein, Rob Knight, Victor Nizet
Publikováno v:
mSystems, Vol 5, Iss 5 (2020)
ABSTRACT Antibiotics are a mainstay of modern medicine, but as they kill their target pathogen(s), they often affect the commensal microbiota. Antibiotic-induced microbiome dysbiosis is a growing research focus and health concern, often assessed via
Externí odkaz:
https://doaj.org/article/94d799acd998420094b81a585a2e6543
Autor:
Andre Mu, Glen P. Carter, Lucy Li, Nicole S. Isles, Alison F. Vrbanac, James T. Morton, Alan K. Jarmusch, David P. De Souza, Vinod K. Narayana, Komal Kanojia, Brunda Nijagal, Malcolm J. McConville, Rob Knight, Benjamin P. Howden, Timothy P. Stinear
Publikováno v:
mSystems, Vol 5, Iss 4 (2020)
ABSTRACT Vancomycin-resistant Enterococcus faecium (VREfm) is an emerging antibiotic-resistant pathogen. Strain-level investigations are beginning to reveal the molecular mechanisms used by VREfm to colonize regions of the human bowel. However, the r
Externí odkaz:
https://doaj.org/article/f5003cdaf3f245779749689be636189d
Autor:
Cannon, Birandra K. Sinha, Carl D. Bortner, Alan K. Jarmusch, Erik J. Tokar, Carri Murphy, Xian Wu, Heather Winter, Ronald E.
Publikováno v:
Cells; Volume 12; Issue 12; Pages: 1626
Our recent studies show that the treatment of human ovarian tumor cells with NCX4040 results in significant depletions of cellular glutathione, the formation of reactive oxygen/nitrogen species and cell death. NCX4040 is also cytotoxic to several hum
Autor:
Julia M. Gauglitz, Kiana A. West, Wout Bittremieux, Candace L. Williams, Kelly C. Weldon, Morgan Panitchpakdi, Francesca Di Ottavio, Christine M. Aceves, Elizabeth Brown, Nicole C. Sikora, Alan K. Jarmusch, Cameron Martino, Anupriya Tripathi, Michael J. Meehan, Kathleen Dorrestein, Justin P. Shaffer, Roxana Coras, Fernando Vargas, Lindsay DeRight Goldasich, Tara Schwartz, MacKenzie Bryant, Gregory Humphrey, Abigail J. Johnson, Katharina Spengler, Pedro Belda-Ferre, Edgar Diaz, Daniel McDonald, Qiyun Zhu, Emmanuel O. Elijah, Mingxun Wang, Clarisse Marotz, Kate E. Sprecher, Daniela Vargas-Robles, Dana Withrow, Gail Ackermann, Lourdes Herrera, Barry J. Bradford, Lucas Maciel Mauriz Marques, Juliano Geraldo Amaral, Rodrigo Moreira Silva, Flavio Protasio Veras, Thiago Mattar Cunha, Rene Donizeti Ribeiro Oliveira, Paulo Louzada-Junior, Robert H. Mills, Paulina K. Piotrowski, Stephanie L. Servetas, Sandra M. Da Silva, Christina M. Jones, Nancy J. Lin, Katrice A. Lippa, Scott A. Jackson, Rima Kaddurah Daouk, Douglas Galasko, Parambir S. Dulai, Tatyana I. Kalashnikova, Curt Wittenberg, Robert Terkeltaub, Megan M. Doty, Jae H. Kim, Kyung E. Rhee, Julia Beauchamp-Walters, Kenneth P. Wright, Maria Gloria Dominguez-Bello, Mark Manary, Michelli F. Oliveira, Brigid S. Boland, Norberto Peporine Lopes, Monica Guma, Austin D. Swafford, Rachel J. Dutton, Rob Knight, Pieter C. Dorrestein
Publikováno v:
Nature biotechnology, vol 40, iss 12
Nat Biotechnol
Nat Biotechnol
Human untargeted metabolomics studies annotate only ~10% of molecular features. We introduce reference-data-driven analysis to match metabolomics tandem mass spectrometry (MS/MS) data against metadata-annotated source data as a pseudo-MS/MS reference