Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Alan K Jarmusch"'
Autor:
Justin B. Collier, Hong Soon Kang, Yun-Gil Roh, Chitrangda Srivastava, Sara A. Grimm, Alan K. Jarmusch, Anton M. Jetten
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102052- (2024)
Objectives: Deficiency in the transcription factor (TF) GLI-Similar 3 (GLIS3) in humans and mice leads to the development of polycystic kidney disease (PKD). In this study, we investigate the role of GLIS3 in the regulation of energy metabolism and m
Externí odkaz:
https://doaj.org/article/a8e70fb81db8452f9739f621caf1bb2c
Autor:
Wout Bittremieux, Nicole E. Avalon, Sydney P. Thomas, Sarvar A. Kakhkhorov, Alexander A. Aksenov, Paulo Wender P. Gomes, Christine M. Aceves, Andrés Mauricio Caraballo-Rodríguez, Julia M. Gauglitz, William H. Gerwick, Tao Huan, Alan K. Jarmusch, Rima F. Kaddurah-Daouk, Kyo Bin Kang, Hyun Woo Kim, Todor Kondić, Helena Mannochio-Russo, Michael J. Meehan, Alexey V. Melnik, Louis-Felix Nothias, Claire O’Donovan, Morgan Panitchpakdi, Daniel Petras, Robin Schmid, Emma L. Schymanski, Justin J. J. van der Hooft, Kelly C. Weldon, Heejung Yang, Shipei Xing, Jasmine Zemlin, Mingxun Wang, Pieter C. Dorrestein
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Despite the increasing availability of tandem mass spectrometry (MS/MS) community spectral libraries for untargeted metabolomics over the past decade, the majority of acquired MS/MS spectra remain uninterpreted. To further aid in interpretin
Externí odkaz:
https://doaj.org/article/1eb1ab39bd1848068d742dc4af2edb11
Autor:
Wout Bittremieux, Rohit S. Advani, Alan K. Jarmusch, Shaden Aguirre, Aileen Lu, Pieter C. Dorrestein, Shirley M. Tsunoda
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 3, Pp 761-770 (2022)
Abstract Chemicals, including some systemically administered xenobiotics and their biotransformations, can be detected noninvasively using skin swabs and untargeted metabolomics analysis. We sought to understand the principal drivers that determine w
Externí odkaz:
https://doaj.org/article/b3f42232b8ac4c599a142dee4192cef6
Autor:
Tim Ken Mackey, Alan K Jarmusch, Qing Xu, Kunyang Sun, Aileen Lu, Shaden Aguirre, Jessica Lim, Simran Bhakta, Pieter C Dorrestein
Publikováno v:
JMIR Public Health and Surveillance, Vol 8, Iss 12, p e41834 (2022)
BackgroundAntimicrobial resistance is a significant global public health threat. However, the impact of sourcing potentially substandard and falsified antibiotics via the internet remains understudied, particularly in the context of access to and qua
Externí odkaz:
https://doaj.org/article/fab7ec3a098c4267be3d4199d8024e30
Autor:
Birandra K. Sinha, Carl D. Bortner, Alan K. Jarmusch, Erik J. Tokar, Carri Murphy, Xian Wu, Heather Winter, Ronald E. Cannon
Publikováno v:
Cells, Vol 12, Iss 12, p 1626 (2023)
Our recent studies show that the treatment of human ovarian tumor cells with NCX4040 results in significant depletions of cellular glutathione, the formation of reactive oxygen/nitrogen species and cell death. NCX4040 is also cytotoxic to several hum
Externí odkaz:
https://doaj.org/article/a81615ed59ff4015be0775e09dc25c83
Autor:
Robin Schmid, Daniel Petras, Louis-Félix Nothias, Mingxun Wang, Allegra T. Aron, Annika Jagels, Hiroshi Tsugawa, Johannes Rainer, Mar Garcia-Aloy, Kai Dührkop, Ansgar Korf, Tomáš Pluskal, Zdeněk Kameník, Alan K. Jarmusch, Andrés Mauricio Caraballo-Rodríguez, Kelly C. Weldon, Melissa Nothias-Esposito, Alexander A. Aksenov, Anelize Bauermeister, Andrea Albarracin Orio, Carlismari O. Grundmann, Fernando Vargas, Irina Koester, Julia M. Gauglitz, Emily C. Gentry, Yannick Hövelmann, Svetlana A. Kalinina, Matthew A. Pendergraft, Morgan Panitchpakdi, Richard Tehan, Audrey Le Gouellec, Gajender Aleti, Helena Mannochio Russo, Birgit Arndt, Florian Hübner, Heiko Hayen, Hui Zhi, Manuela Raffatellu, Kimberly A. Prather, Lihini I. Aluwihare, Sebastian Böcker, Kerry L. McPhail, Hans-Ulrich Humpf, Uwe Karst, Pieter C. Dorrestein
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Abstract Molecular networking connects mass spectra of molecules based on the similarity of their fragmentation patterns. However, during ionization, molecules commonly form multiple ion species with different fragmentation behavior. As a result, the
Externí odkaz:
https://doaj.org/article/c79c811ddd0b40428c0ef8e4c5a7fe4c
Autor:
Roxana Coras, Cameron Martino, Julia M. Gauglitz, Francesca Cedola, Anupriya Tripathi, Alan K. Jarmusch, Maram Alharthi, Marta Fernandez‐Bustamante, Meritxell Agustin‐Perez, Abha Singh, Soo‐In Choi, Tania Rivera, Katherine Nguyen, Tatyana Shekhtman, Tiffany Holt, Susan Lee, Shahrokh Golshan, Pieter C. Dorrestein, Rob Knight, Monica Guma
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 7, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/060d7b5c223449169399b643b94f466f
Autor:
Andre Mu, Daniel McDonald, Alan K. Jarmusch, Cameron Martino, Caitriona Brennan, Mackenzie Bryant, Gregory C. Humphrey, Julia Toronczak, Tara Schwartz, Dominic Nguyen, Gail Ackermann, Anthony D’Onofrio, Steffanie A. Strathdee, Robert T. Schooley, Pieter C. Dorrestein, Rob Knight, Saima Aslam
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-8 (2021)
Abstract Background Infectious bacterial diseases exhibiting increasing resistance to antibiotics are a serious global health issue. Bacteriophage therapy is an anti-microbial alternative to treat patients with serious bacterial infections. However,
Externí odkaz:
https://doaj.org/article/427b76349aaa475d98112b027db52245
Autor:
Alan K. Jarmusch, Alison Vrbanac, Jeremiah D. Momper, Joseph D. Ma, Maher Alhaja, Marlon Liyanage, Rob Knight, Pieter C. Dorrestein, Shirley M. Tsunoda
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 5, Pp 972-984 (2020)
Determining factors that contribute to interindividual and intra‐individual variability in pharmacokinetics (PKs) and drug metabolism is essential for the optimal use of drugs in humans. Intestinal microbes are important contributors to variability
Externí odkaz:
https://doaj.org/article/4fae86d0d1c641e49a64ed7b6b51323f
Autor:
Morgan Panitchpakdi, Kelly C. Weldon, Alan K. Jarmusch, Emily C. Gentry, Arianna Choi, Yadira Sepulveda, Shaden Aguirre, Kunyang Sun, Jeremiah D. Momper, Pieter C. Dorrestein, Shirley M. Tsunoda
Publikováno v:
PLoS ONE, Vol 17, Iss 7 (2022)
Clinical testing typically relies on invasive blood draws and biopsies. Alternative methods of sample collection are continually being developed to improve patient experience; swabbing the skin is one of the least invasive sampling methods possible.
Externí odkaz:
https://doaj.org/article/d127b390ce8e45eb868dec29462c4c88