Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Alan J. Ryan"'
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 9, Pp 1758-1767 (2004)
Alveolar type II lung epithelia produce surfactant, an essential surface-active material highly enriched with disaturated phosphatidylcholine (DSPC), which requires a key regulatory enzyme, CTP:phosphocholine cytidylyltransferase α (CCTα), for its
Externí odkaz:
https://doaj.org/article/f6448f8e8a5e4fef936fc544adf9d1a3
Lipoprotein deprivation stimulates transcription of the CTP:phosphocholine cytidylyltransferase gene
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 8, Pp 1268-1277 (2000)
We examined the effect of lipoprotein deprivation on the expression of the rate-regulatory enzyme involved in phosphatidylcholine (PtdCho) synthesis, phosphocholine cytidylyltransferase (CCT), within an alveolar type II epithelial cell line (MLE-12).
Externí odkaz:
https://doaj.org/article/26bcd9afb9f241e38364d8701f2aea87
Autor:
Daniel M. Collier, Zerubbabel J. Peterson, Alan J. Ryan, Noah N. Williford, Christopher J. Benson, Peter M. Snyder
Salt is often used to enhance the flavor of foods and drinks, and in turn, some foods and drinks may intensify the taste of salt. For example, highly acidic carbonated beverages sometimes accompany salty snacks, and margaritas made with acidic citrus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25baa318488c640a687a2f39316b6402
https://doi.org/10.1101/2023.04.14.536795
https://doi.org/10.1101/2023.04.14.536795
Publikováno v:
Acta Biomaterialia. 112:52-61
This article describes the development of a hierarchical biofabrication technique suitable to create large but complex structures, such as vascular mimicking grafts, using facile lyophilisation technology amenable to multiple other biomaterial classe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efaf4c2171eb118562d8cfd8c3abc22
https://doi.org/10.1016/j.actbio.2020.06.002
https://doi.org/10.1016/j.actbio.2020.06.002
Autor:
Holly Hohmann, Alan J. Ryan, Nandita S. Raikwar, Trever Maiers, Peter M. Snyder, Sailesh C. Harwani
Publikováno v:
Hypertension. 78
Inflammation plays a key role in the pathogenesis of hypertension. High dietary sodium intake has been associated with inflammation in patients suffering from high blood pressure & atherosclerosis. Our lab has shown that development of hypertension i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4113b4714a7e2d23b951c0c773f4e413
https://doi.org/10.1161/hyp.78.suppl_1.p216
https://doi.org/10.1161/hyp.78.suppl_1.p216
Autor:
Peter M. Snyder, Sailesh C. Harwani, Trever Maiers, Nandita S. Raikwar, Holly Hohmann, Alan J. Ryan
Publikováno v:
Hypertension. 78
Hypertension is a major cause of premature death worldwide. Inflammatory macrophages play a key role in the pathogenesis of hypertension. Our lab has observed that nicotinic acetylcholine receptors (nAChR) activation potentiates salt-sensitive hypert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8da321c8c5510070a3d1ec9e5044ddb
https://doi.org/10.1161/hyp.78.suppl_1.p213
https://doi.org/10.1161/hyp.78.suppl_1.p213
Autor:
Valeria Nicolosi, Christopher Hobbs, Fergal J. O'Brien, Emily J. Ryan, Francesca E. Ciraldo, Alan J. Ryan, Aldo R. Boccaccini, Anahí Philippart, Cathal J. Kearney, Arlyng González-Vázquez
Publikováno v:
Biomaterials. 197:405-416
The bone infection osteomyelitis (typically by Staphylococcus aureus) usually requires a multistep procedure of surgical debridement, long-term systemic high-dose antibiotics, and - for larger defects - bone grafting. This, combined with the alarming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1739e75e74c5fe329d3f44e5224e01e
https://doi.org/10.1016/j.biomaterials.2019.01.031
https://doi.org/10.1016/j.biomaterials.2019.01.031
Publikováno v:
ACS biomaterials scienceengineering. 3(7)
Peripheral nerve injuries have high incidence rates, limited treatment options and poor clinical outcomes, rendering a significant socioeconomic burden. For effective peripheral nerve repair, the gap or site of injury must be structurally bridged to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58285b8c1ad043fcc276c2cc0c8392e7
https://pubmed.ncbi.nlm.nih.gov/33440511
https://pubmed.ncbi.nlm.nih.gov/33440511
Autor:
Fergal J. O'Brien, Justin S. Weinbaum, Jochen Hess, Niall F. Davis, Michael Walsh, Katherine L. Lorentz, David A. Vorp, Connor V. Cunnane, Alan J. Ryan, Eoghan M. Cunnane
Publikováno v:
Biomaterials
This study addresses a crucial gap in the literature by characterising the relationship between urethral tissue mechanics, composition and gross structure. We then utilise these data to develop a biomimetic urethral scaffold with physical properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6282d471d3b16b0771815b140c91a344
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85099506582
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85099506582
Olfactory Derived Stem Cells Delivered in a Biphasic Conduit Promote Peripheral Nerve Repair In Vivo
Autor:
Amos Matsiko, Phoebe Roche, Fergal J. O'Brien, Amro Widaa, Michael Walsh, Alan J. Ryan, Garry P. Duffy, Tijna Alekseeva
Publikováno v:
Stem Cells Translational Medicine
Peripheral nerve injury presents significant therapeutic challenges for recovery of motor and sensory function in patients. Different clinical approaches exist but to date there has been no consensus on the most effective method of treatment. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e76f2ffdae84426d770b7744b5b74c
http://europepmc.org/articles/PMC6430049
http://europepmc.org/articles/PMC6430049