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pro vyhledávání: '"Alan J. Pawlak"'
Autor:
Alan J. Pawlak, Mark L. Dietz
Publikováno v:
Separation Science and Technology. 49:2847-2855
The most commonly studied classes of ionic liquids (ILs) comprise relatively large and asymmetric heterocyclic cations (e.g., diakylimidazolium or N-alkylpyridinium) in combination with any of a wide variety of inorganic (e.g., BF4−, Cl−) or orga
Autor:
David J. Maloney, Adam Yasgar, William R. Shadrick, Leggy A. Arnold, Alan J. Pawlak, Anton Simeonov, Ajit Jadhav, Megan M. McCallum
Publikováno v:
Analytical and Bioanalytical Chemistry. 406:1867-1875
Herein, we describe the development of a fluorescence-based high throughput assay to determine the small molecule binding towards human serum albumin (HSA). This innovative competition assay is based on the use of a novel fluorescent small molecule R
Autor:
Daniel D. Bikle, Belaynesh Feleke, Adam Yasgar, Ajit Jadhav, Anton Simeonov, Chinedum Kevin, Ganesha Rai, Preetpal S. Sidhu, Premchendar Nandhikonda, David G. Maloney, Nina Y. Yuan, Alan J. Pawlak, Athena M. Baranowski, Megan M. McCallum, Paul Webb, Stephen D. Ayers, Kelly A. Teske, Leggy A. Arnold
Publikováno v:
Biochemistry, vol 52, iss 24
A high-throughput screening campaign was conducted to identify small molecules with the ability to inhibit the interaction between the vitamin D receptor (VDR) and steroid receptor coactivator 2. These inhibitors represent novel molecular probes for