Zobrazeno 1 - 10
of 644
pro vyhledávání: '"Alan J Thompson"'
Autor:
Alan J Thompson, Charles Wade, Nevin John, Jeremy Chataway, Gavin Giovannoni, Rachael Hunter, Sreedharan Harikrishnan, Floriana De Angelis, Olga Ciccarelli, Eli Silber, John Greenwood, Thomas Williams, Martin Duddy, Basil Sharrack, Annie Hawton, Siddharthan Chandran, Sue Pavitt, Paul Gallagher, Ian Galea, Jennifer M Nicholas, Tarunya Arun, Miriam Mattoscio, Richard Nicholas, Neil Robertson, Carolyn Young, Jeremy Hobart, David Rog, Owen Pearson, Anisha Doshi, Timothy Harrower, Leonora Fisniku, Ruth Geraldes, Nikos Evangelou, Judy Beveridge, Matthew Craner, Don Mahad, Stefano Pluchino, Suresh Chhetri, Susan Tebbs, Marie Braisher, Seema Kalra, Charles Hillier, Chris Frost, Gavin McDonnell, Stuart J Nixon, Helen L Ford, Jeban Ganesalingam, Claire Rice, Alberto Calvi, Cord Spilker, Abdullah Shehu, Martin Lee, James Blackstone, Alessia Bianchi, Agne Straukiene, Gil Barton, Fayyaz Ahmed, Dawn Lyle, Ekaterina Bordea, Sean Apap Mangion, Rachel Merry, Elisabeth Jarman
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Introduction There remains a high unmet need for disease-modifying therapies that can impact disability progression in secondary progressive multiple sclerosis (SPMS). Following positive results of the phase 2 MS-STAT study, the MS-STAT2 phase 3 tria
Externí odkaz:
https://doaj.org/article/69619bde66e34a6986cbeaf0b8bdc802
Autor:
Martin Rakusa, Stefan J Cano, Bernadette Porter, Afsane Riazi, Alan J Thompson, Jeremy Chataway, Todd A Hardy
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120829 (2015)
To derive a simple predictive model to guide the use of corticosteroids in patients with relapsing remitting MS suffering an acute relapse.We analysed individual patient randomised controlled trial data (n=98) using a binary logistic regression model
Externí odkaz:
https://doaj.org/article/df84cca72d5a481284869f5b49bf1d71
Autor:
Khaled Abdel-Aziz, Bhavana S Solanky, Marios C Yiannakas, Daniel R Altmann, Claudia A M Wheeler-Kingshott, Alan J Thompson, Olga Ciccarelli
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e105774 (2014)
Magnetic resonance spectroscopy (MRS) studies have previously described metabolite changes associated with aging of the healthy brain and provided insights into normal brain aging that can assist us in differentiating age-related changes from those a
Externí odkaz:
https://doaj.org/article/45dfd4784dea45ad975fbdab7d498968
Autor:
Patrick Freund, Torben Schneider, Zoltan Nagy, Chloe Hutton, Nikolaus Weiskopf, Karl Friston, Claudia A Wheeler-Kingshott, Alan J Thompson
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51729 (2012)
Traumatic spinal cord injury (SCI) leads to disruption of axons and macroscopic tissue loss. Using diffusion tensor imaging (DTI), we assessed degeneration of the corticospinal tract (CST) in the cervical cord above a traumatic lesion and explored it
Externí odkaz:
https://doaj.org/article/d50a53f5d7894094aefc175fa8465148
The Exegetical Guide to the Greek New Testament (EGGNT) closes the gap between the Greek text and the available lexical and grammatical tools, providing all the necessary information for greater understanding of the text. The series makes interpretin
Autor:
Tanja Kuhlmann, Marcello Moccia, Timothy Coetzee, Jeffrey A Cohen, Jorge Correale, Jennifer Graves, Ruth Ann Marrie, Xavier Montalban, V Wee Yong, Alan J Thompson, Daniel S Reich, Maria Pia Amato, Brenda Banwell, Frederik Barkhof, Jeremy Chataway, Tanuja Chitnis, Giancarlo Comi, Tobias Derfuss, Marcia Finlayson, Myla Goldman, Ari Green, Kerstin Hellwig, Daphne Kos, Aaron Miller, Ellen Mowry, Jiwon Oh, Amber Salter, Maria Pia Sormani, Mar Tintore, Helen Tremlett, Maria Trojano, Anneke van der Walt, Sandra Vukusic, Emmaunelle Waubant
Publikováno v:
International Advisory Committee on Clinical Trials in Multiple Sclerosis 2023, ' Multiple sclerosis progression : time for a new mechanism-driven framework ', The Lancet Neurology, vol. 22, no. 1, pp. 78-88 . https://doi.org/10.1016/S1474-4422(22)00289-7
Traditionally, multiple sclerosis has been categorised by distinct clinical descriptors—relapsing-remitting, secondary progressive, and primary progressive—for patient care, research, and regulatory approval of medications. Accumulating evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c95d190a07ae620fd13c1f9545253e9
https://doi.org/10.1016/s1474-4422(22)00289-7
https://doi.org/10.1016/s1474-4422(22)00289-7
Autor:
Allen C. Bowling, MD, PhD, Dr. T. Jock Murray, MS, John H. Noseworthy, MD, Chris H. Polman, MD, PhD, Alan J. Thompson, MD, FRCP, FRCPI
The huge expansion of information available about MS, especially through the Internet, has put the individual with MS in a position to take increasing responsibility for her or his own care. There is thus a need for a comprehensive, readily accessibl
Paradigm shifts: Early initiation of high-efficacy disease-modifying treatment in multiple sclerosis
Publikováno v:
Multiple Sclerosis Journal. 27:1473-1476
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5109f9da7a85166d7c846339fde6d7aa
https://doi.org/10.1177/13524585211033190
https://doi.org/10.1177/13524585211033190
Autor:
Lukas Haider, Marios C. Yiannakas, Claudia A. M. Wheeler-Kingshott, Frederik Barkhof, Carole H. Sudre, Declan T. Chard, Baris Kanber, Alan J. Thompson, Olga Ciccarelli, Karen Chung, Rebecca S. Samson, Stephanie Mangesius, Ferran Prados, Olivia Goodkin
Publikováno v:
Brain, 144(5), 1384-1395. Oxford University Press
Brain
Haider, L, Prados, F, Chung, K, Goodkin, O, Kanber, B, Sudre, C, Yiannakas, M, Samson, R S, Mangesius, S, Thompson, A J, Gandini Wheeler-Kingshott, C A M, Ciccarelli, O, Chard, D T & Barkhof, F 2021, ' Cortical involvement determines impairment 30 years after a clinically isolated syndrome ', Brain, vol. 144, no. 5, pp. 1384-1395 . https://doi.org/10.1093/brain/awab033, https://doi.org/10.1093/brain/awab033
Brain, Vol. 144, no. 5, p. 1384-1395 (2021)
Brain
Haider, L, Prados, F, Chung, K, Goodkin, O, Kanber, B, Sudre, C, Yiannakas, M, Samson, R S, Mangesius, S, Thompson, A J, Gandini Wheeler-Kingshott, C A M, Ciccarelli, O, Chard, D T & Barkhof, F 2021, ' Cortical involvement determines impairment 30 years after a clinically isolated syndrome ', Brain, vol. 144, no. 5, pp. 1384-1395 . https://doi.org/10.1093/brain/awab033, https://doi.org/10.1093/brain/awab033
Brain, Vol. 144, no. 5, p. 1384-1395 (2021)
Many studies report an overlap of MRI and clinical findings between patients with relapsing-remitting multiple sclerosis (RRMS) and secondary progressive multiple sclerosis (SPMS), which in part is reflective of inclusion of subjects with variable di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677b9a5377c034797df6d63e813f0307
https://doi.org/10.1093/brain/awab033
https://doi.org/10.1093/brain/awab033
Autor:
Alan J. Thompson, Jonas Pichat, Olga Ciccarelli, Lukas Haider, Claudia A. M. Wheeler-Kingshott, Steven H. P. van de Pavert, Sebastien Ourselin, Arman Eshaghi, Marcello Moccia, Frederik Barkhof, Marios C. Yiannakas, Yi Wang
Publikováno v:
Neurology, 95(22), e2965-e2976. Lippincott Williams and Wilkins
Moccia, M, van de Pavert, S, Eshaghi, A, Haider, L, Pichat, J, Yiannakas, M, Ourselin, S, Wang, Y, Wheeler-Kingshott, C, Thompson, A, Barkhof, F & Ciccarelli, O 2020, ' Pathologic correlates of the magnetization transfer ratio in multiple sclerosis ', Neurology, vol. 95, no. 22, pp. e2965-e2976 . https://doi.org/10.1212/WNL.0000000000010909
Moccia, M, van de Pavert, S, Eshaghi, A, Haider, L, Pichat, J, Yiannakas, M, Ourselin, S, Wang, Y, Wheeler-Kingshott, C, Thompson, A, Barkhof, F & Ciccarelli, O 2020, ' Pathologic correlates of the magnetization transfer ratio in multiple sclerosis ', Neurology, vol. 95, no. 22, pp. e2965-e2976 . https://doi.org/10.1212/WNL.0000000000010909
ObjectiveTo identify pathologic correlates of magnetization transfer ratio (MTR) in multiple sclerosis (MS) in an MRI–pathology study.MethodsWe acquired MTR maps at 3T from 16 fixed MS brains and 4 controls, and immunostained 100 tissue blocks for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f60dedb6427104af3b4a08dc76836179
http://www.scopus.com/inward/record.url?scp=85097004277&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85097004277&partnerID=8YFLogxK