Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Alan J Kivitz"'
Publikováno v:
Rheumatology and Therapy, Vol 11, Iss 3, Pp 675-689 (2024)
Abstract Introduction The aim of this work is to evaluate secukinumab vs. placebo in a challenging-to-treat and smaller US patient subpopulation of the international FUTURE 2–5 studies in patients with psoriatic arthritis (PsA). Methods Data were p
Externí odkaz:
https://doaj.org/article/82e8a3c103fb46598b98d83425a76465
Publikováno v:
SAGE Open Medicine, Vol 2 (2014)
Objective: To assess usability, bioavailability, and safety of subcutaneous self-administration of 0.3 mL of methotrexate 50 mg/mL solution via a prefilled autoinjector pen (methotrexate pen) in patients with rheumatoid arthritis. Methods: The study
Externí odkaz:
https://doaj.org/article/96a9468908cf48bea6d3015dbf05f5d9
Autor:
Bernard G. Combe, Yoshiya Tanaka, Maya H. Buch, Peter Nash, Gerd R. Burmester, Alan J. Kivitz, Beatrix Bartok, Alena Pechonkina, Katrina Xia, Kahaku Emoto, Shungo Kano, Thijs K. Hendrikx, Robert B. M. Landewé, Daniel Aletaha
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 1, Pp 53-70 (2022)
Abstract Introduction This exploratory analysis of FINCH 1 (NCT02889796) examined filgotinib (FIL) efficacy and safety in a subgroup of patients with rheumatoid arthritis (RA) and inadequate response to methotrexate (MTX; MTX-IR) who had four poor pr
Externí odkaz:
https://doaj.org/article/d5f278750ece4369b8287f893aae3cee
Autor:
Lubna Abuqayyas, Laurence E. Cheng, Marcia Teixeira dos Santos, Barbara A. Sullivan, Norma Ruiz‐Santiago, Hui Wang, Yanchen Zhou, Vishala Chindalore, Stanley Cohen, Alan J. Kivitz, Maximilian G. Posch, Jane R. Parnes
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 10, Pp 903-911 (2022)
Objective To assess the safety and biological activity of rozibafusp alfa, a first‐in‐class bispecific antibody–peptide conjugate targeting inducible costimulator ligand (ICOSL) and B cell activating factor (BAFF), in patients with rheumatoid a
Externí odkaz:
https://doaj.org/article/5676c94a2dbb4dc3a8d16a7cdd33da21
Autor:
Bernard G. Combe, Yoshiya Tanaka, Maya H. Buch, Peter Nash, Gerd R. Burmester, Alan J. Kivitz, Beatrix Bartok, Alena Pechonkina, Katrina Xia, Kahaku Emoto, Shungo Kano, Thijs K. Hendrikx, Robert B. M. Landewé, Daniel Aletaha
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 1, Pp 71-72 (2023)
Externí odkaz:
https://doaj.org/article/482e0de723eb4725b687f0331d72bd59
Autor:
Martin J. Bergman, Alan J. Kivitz, Dimitrios A. Pappas, Joel M. Kremer, Lixia Zhang, Anna Jeter, Johanna B. Withers
Publikováno v:
Rheumatology and Therapy, Vol 7, Iss 4, Pp 775-792 (2020)
Abstract Introduction The PrismRA® test identifies rheumatoid arthritis (RA) patients who are unlikely to respond to anti-tumor necrosis factor (anti-TNF) therapies. This study evaluated the clinical and financial outcomes of incorporating PrismRA i
Externí odkaz:
https://doaj.org/article/b28f75c23988432186a271042e8f815a
Autor:
Peter Nash, Laura C. Coates, Alan J. Kivitz, Philip J. Mease, Dafna D. Gladman, José A. Covarrubias-Cobos, Oliver FitzGerald, Dona Fleishaker, Cunshan Wang, Joseph Wu, Ming-Ann Hsu, Sujatha Menon, Lara Fallon, Ana Belén Romero, Keith S. Kanik
Publikováno v:
Rheumatology and Therapy, Vol 7, Iss 3, Pp 553-580 (2020)
Abstract Introduction Tofacitinib is an oral Janus kinase inhibitor for the treatment of psoriatic arthritis (PsA). We report the interim safety, tolerability, and efficacy of tofacitinib in PsA patients in OPAL Balance, a 3-year, open-label, long-te
Externí odkaz:
https://doaj.org/article/86b13f128d894de4aa055f152d42c856
Autor:
Alan J. Kivitz, Peter Nash, Hasan Tahir, Andrea Everding, Heřman Mann, Andrzej Kaszuba, Pascale Pellet, Albert Widmer, Luminita Pricop, Ken Abrams
Publikováno v:
Rheumatology and Therapy, Vol 6, Iss 3, Pp 393-407 (2019)
Abstract Introduction To assess the efficacy and safety of the subcutaneous (s.c.) secukinumab 150 mg with loading (150 mg) or without loading (150 mg no-load) regimen through 104 weeks in patients with active psoriatic arthritis (PsA) in the FUTURE
Externí odkaz:
https://doaj.org/article/4baf3af6552740698eb358c503164425
Autor:
Xenofon Baraliakos, Atul Deodhar, Maxime Dougados, Lianne S. Gensler, Anna Molto, Sofia Ramiro, Alan J. Kivitz, Denis Poddubnyy, Marga Oortgiesen, Thomas Vaux, Carmen Fleurinck, Julie Shepherd‐Smith, Christine de la Loge, Natasha de Peyrecave, Désirée van der Heijde
Publikováno v:
Arthritis & Rheumatology. 74:1943-1958
Autor:
Gerd R Burmester, Vibeke Strand, Alan J Kivitz, Chih-Chi Hu, Sheldon Wang, Hubert van Hoogstraten, Gabriella L Klier, Roy Fleischmann
Publikováno v:
Rheumatology.
ObjectiveTo evaluate the long-term safety and efficacy of sarilumab with/without conventional synthetic (cs)DMARDs in RA.MethodsThe analyses evaluated two open-label extensions (OLEs): EXTEND and MONARCH OLE, which included patients from six randomiz