Zobrazeno 1 - 10
of 328
pro vyhledávání: '"Alan J, Wolfe"'
Autor:
Rasa Valiauga, Sarah Talley, Mark Khemmani, Melline Fontes Noronha, Rocco Gogliotti, Alan J. Wolfe, Edward Campbell
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Background Mounting evidence links glucose intolerance and diabetes as aspects of metabolic dysregulation that are associated with an increased risk of developing dementia. Inflammation and inflammasome activation have emerged as a potential
Externí odkaz:
https://doaj.org/article/d840760127004d25a97d8ae91be3fbd9
Autor:
Emma Stewart, Baylie R. Hochstedler-Kramer, Mark Khemmani, Nina M. Clark, Jorge P. Parada, Ahmer Farooq, Chirag Doshi, Alan J. Wolfe, Fritzie S. Albarillo
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT The impact of chronic indwelling urinary catheters (IUCs) on the composition and stability of the urinary microbiota remains unknown. The primary aim of this study was to describe the urinary microbiomes of geriatric males with chronic IUCs.
Externí odkaz:
https://doaj.org/article/6fe802ff2c204527ad499e78306c1b95
Autor:
Hanna E. Walukiewicz, Yuliya Farris, Meagan C. Burnet, Sarah C. Feid, Youngki You, Hyeyoon Kim, Thomas Bank, David Christensen, Samuel H. Payne, Alan J. Wolfe, Christopher V. Rao, Ernesto S. Nakayasu
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Lysine and arginine methylation is an important regulator of enzyme activity and transcription in eukaryotes. However, little is known about this covalent modification in bacteria. In this work, we investigated the role of methylation in bac
Externí odkaz:
https://doaj.org/article/1735fe52424741cba0a5cc8935e3d006
Autor:
Ryan A. Dornbier, Chirag P. Doshi, Shalin C. Desai, Petar Bajic, Michelle Van Kuiken, Mark Khemmani, Ahmer V. Farooq, Larissa Bresler, Thomas M.T. Turk, Alan J. Wolfe, Kristin G. Baldea
Publikováno v:
Asian Journal of Urology, Vol 11, Iss 2, Pp 316-323 (2024)
Objective: To identify possible stone-promoting microbes, we compared the profiles of microbes grown from stones of patients with and without metabolic syndrome (MetS). The association between MetS and urinary stone disease is well established, but t
Externí odkaz:
https://doaj.org/article/812aba10b1ac42dbaee6a93f27ccef49
Autor:
Jingjie Du, Mark Khemmani, Thomas Halverson, Adriana Ene, Roberto Limeira, Lana Tinawi, Baylie R. Hochstedler-Kramer, Melline Fontes Noronha, Catherine Putonti, Alan J. Wolfe
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract Background Although the human bladder is reported to harbor unique microbiota, our understanding of how these microbial communities interact with their human hosts is limited, mostly owing to the lack of isolates to test mechanistic hypothes
Externí odkaz:
https://doaj.org/article/cac50db55def474d91d224f2cf511cc8
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Bacterial isolates from the human urinary microbiome have been extensively studied for their antibiotic resistance; however, little work has been done on those isolates that are difficult to grow in vitro. This study was designed to qualify
Externí odkaz:
https://doaj.org/article/962be53e3707433f917d7f616672a9c1
Autor:
Goran Rac, Hiten D. Patel, Christopher James, Shalin Desai, Vincent M. Caruso, Daniel S. Fischer, Peter S. Lentz, Ceressa T. Ward, Brian C. Mazzarella, Kevin G. Phillips, Chirag Doshi, Vincent T. Bicocca, Trevor G. Levin, Alan J. Wolfe, Gopal N. Gupta
Publikováno v:
Molecular Oncology, Vol 18, Iss 2, Pp 291-304 (2024)
Intravesical therapy (IVT) is the standard of care to decrease risk of recurrence and progression for high‐grade nonmuscle‐invasive bladder cancer. However, post‐IVT recurrence remains common and the ability to risk‐stratify patients before o
Externí odkaz:
https://doaj.org/article/d353b6be5cfb4f84b1c4d2ba8274a89c
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Enterococcus faecalis is the most commonly isolated enterococcal species in clinical infection. This bacterium is notorious for its ability to share genetic content within and outside of its species. With this increased proficienc
Externí odkaz:
https://doaj.org/article/07dcc838e4ed4e72b7b22553d4db51d1
Autor:
Genevieve Baddoo, Adriana Ene, Zubia Merchant, Swarnali Banerjee, Alan J. Wolfe, Catherine Putonti
Publikováno v:
Frontiers in Urology, Vol 3 (2024)
Continued efforts to isolate and sequence bacteria of the urinary tract has increased representation of these species in publicly available databases. This in turn has improved taxonomic classifications of the urinary microbiome (urobiome). Short-rea
Externí odkaz:
https://doaj.org/article/01dbfe6ed4e348589620c19c7339b5c5
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2024)
With the advent of next generation sequencing, it is now appreciated that human urine is not sterile. Recent investigations of the urinary microbiome (urobiome) have provided insights into several urological diseases. Urobiome dysbiosis, defined as n
Externí odkaz:
https://doaj.org/article/d1036285d1604753a07a7c774a2d5d00