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Autor:
Edward J. Smith, Michael Ruberto, James Castner, Alan Hendricker, Christopher Houston, Daniel L. Norwood, Tom Feinberg, Kumudini Nicholas, Michael P. Lynch, Dennis Jenke, Diane Paskiet, Thomas Egert, Desmond G. Hunt, Ingrid Markovic, Frank Holcomb
Publikováno v:
PDA Journal of Pharmaceutical Science and Technology. 71:68-87
A simulating leaching (migration) study was performed on a model container-closure system relevant to parenteral and ophthalmic drug products. This container-closure system consisted of a linear low-density polyethylene bottle (primary container), a