Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Alan H Lazarus"'
Autor:
Lazaro Gil Gonzalez, Yuniel Fernandez-Marrero, Peter Alan Albert Norris, Zoya Tawhidi, Yuexin Shan, Yoelys Cruz-Leal, Kevin Doyoon Won, Kayluz Frias-Boligan, Donald R Branch, Alan H Lazarus
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278365 (2022)
Fc gamma receptors (FcγRs) are critical effector receptors for immunoglobulin G (IgG) antibodies. On macrophages, FcγRs mediate multiple effector functions, including phagocytosis, but the individual contribution of specific FcγRs to phagocytosis
Externí odkaz:
https://doaj.org/article/f7265e142eef41cd8ec7a105aae32787
Autor:
Patrick J Mott, Alan H Lazarus
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65805 (2013)
Antibodies to CD44 have been used to successfully ameliorate murine models of autoimmune disease. The most often studied disease model has been murine inflammatory arthritis, where a clear mechanism for the efficacy of CD44 antibodies has not been es
Externí odkaz:
https://doaj.org/article/0730c2660fa74aff804b8122f0c3c6e5
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71882 (2013)
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by a low platelet count and the production of anti-platelet antibodies. The majority of ITP patients have antibodies to platelet integrin α(IIb)β₃ (GPIIbIIIa) which ca
Externí odkaz:
https://doaj.org/article/65027d08a6b143549c4606c6147756a4
Autor:
John W Semple, Michael Kim, Jing Hou, Mark McVey, Young Jin Lee, Arata Tabuchi, Wolfgang M Kuebler, Zhong-Wei Chai, Alan H Lazarus
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31357 (2012)
Transfusion-related acute lung injury (TRALI) is a leading cause of transfusion-associated mortality that can occur with any type of transfusion and is thought to be primarily due to donor antibodies activating pulmonary neutrophils in recipients. Re
Externí odkaz:
https://doaj.org/article/35d1e224f65c419da6547570763608d3
Publikováno v:
Transfusion. 63:696-702
Publikováno v:
Transfusion. 63:619-628
Despite the vast antigen disparity between donor and recipient red blood cells (RBCs), only 2%-6% of transfusion patients mount an alloantibody response. Recently, RBC antigen density has been proposed as one of the factors that can influence alloimm
Autor:
Peter A. A. Norris, George B. Segel, W. Richard Burack, Ulrich J. Sachs, Suzanne N. Lissenberg-Thunnissen, Gestur Vidarsson, Behnaz Bayat, Christine M. Cserti-Gazdewich, Jeannie Callum, Yulia Lin, Donald Branch, Rick Kapur, John W. Semple, Alan H. Lazarus
Publikováno v:
Haematologica, Vol 106, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/771986d585e448e1a0715204745ac32b
Autor:
Richard Vollenberg, Rabie Jouni, Peter A. A. Norris, Monika Burg-Roderfeld, Nina Cooper, Mathias J. Rummel, Gregor Bein, Irene Marini, Behnaz Bayat, Richard Burack, Alan H. Lazarus, Tamam Bakchoul, Ulrich J. Sachs
Publikováno v:
Haematologica, Vol 104, Iss 6 (2019)
Platelet autoantibody-induced platelet clearance represents a major pathomechanism in immune thrombocytopenia (ITP). There is growing evidence for clinical differences between anti-glycoprotein IIb/IIIa and anti-glycoprotein Ib/IX mediated ITP. Glyco
Externí odkaz:
https://doaj.org/article/c7970fdffc1e498880f07c0ac1c89172
Autor:
Peter Alan Albert Norris, Zoya Tawhidi, Ulrich J. Sachs, Christine M Cserti-Gazdewich, Yulia Lin, Jeannie L Callum, Lazaro Gil Gonzalez, Yuexin Shan, Donald R. Branch, Alan H Lazarus
Publikováno v:
Blood Advances.
Humoral anti-platelet factors such as autoantibodies are thought to primarily clear platelets by triggering macrophage phagocytosis in immune thrombocytopenia (ITP). However, there are scarce studies characterizing the capacity and mechanisms of humo
Publikováno v:
British Journal of Haematology.